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Items: 1 to 20 of 93


Bursting Enables GRP Neurons to Engage Spinal Itch Circuits.

Petitjean H, Séguéla P, Sharif-Naeini R.

Neuron. 2019 Aug 7;103(3):546. doi: 10.1016/j.neuron.2019.07.012. No abstract available.


Bursting Enables GRP Neurons to Engage Spinal Itch Circuits.

Petitjean H, Séguéla P, Sharif-Naeini R.

Neuron. 2019 Jul 3;103(1):5-7. doi: 10.1016/j.neuron.2019.06.009. Erratum in: Neuron. 2019 Aug 7;103(3):546.


An Allosteric Inhibitory Site Conserved in the Ectodomain of P2X Receptor Channels.

Ase AR, Therrien É, Séguéla P.

Front Cell Neurosci. 2019 Apr 9;13:121. doi: 10.3389/fncel.2019.00121. eCollection 2019.


Agmatine preferentially antagonizes GluN2B-containing N-methyl-d-aspartate receptors in spinal cord.

Waataja JJ, Peterson CD, Verma H, Goracke-Postle CJ, Séguéla P, Delpire E, Wilcox GL, Fairbanks CA.

J Neurophysiol. 2019 Feb 1;121(2):662-671. doi: 10.1152/jn.00172.2018. Epub 2018 Nov 14.


Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus.

Glasgow SD, Labrecque S, Beamish IV, Aufmkolk S, Gibon J, Han D, Harris SN, Dufresne P, Wiseman PW, McKinney RA, Séguéla P, De Koninck P, Ruthazer ES, Kennedy TE.

Cell Rep. 2018 Oct 2;25(1):168-182.e6. doi: 10.1016/j.celrep.2018.09.028.


The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons.

Thomas RA, Gibon J, Chen CXQ, Chierzi S, Soubannier VG, Baulac S, Séguéla P, Murai K, Barker PA.

eNeuro. 2018 Sep 7;5(4). pii: ENEURO.0185-18.2018. doi: 10.1523/ENEURO.0185-18.2018. eCollection 2018 Jul-Aug.


The CaV2α1 EF-hand F helix tyrosine, a highly conserved locus for GPCR inhibition of CaV2 channels.

Dunn TW, Fan X, Ase AR, Séguéla P, Sossin WS.

Sci Rep. 2018 Feb 19;8(1):3263. doi: 10.1038/s41598-018-21586-5.


Noradrenergic fiber sprouting and altered transduction in neuropathic prefrontal cortex.

Cordeiro Matos S, Zamfir M, Longo G, Ribeiro-da-Silva A, Séguéla P.

Brain Struct Funct. 2018 Apr;223(3):1149-1164. doi: 10.1007/s00429-017-1543-7. Epub 2017 Nov 1.


P2X receptor channels in chronic pain pathways.

Bernier LP, Ase AR, Séguéla P.

Br J Pharmacol. 2018 Jun;175(12):2219-2230. doi: 10.1111/bph.13957. Epub 2017 Aug 17. Review.


Will optogenetics be used to treat chronic pain patients?

Beaudry H, Daou I, Ribeiro-da-Silva A, Séguéla P.

Pain Manag. 2017 Jul;7(4):269-278. doi: 10.2217/pmt-2016-0055. Epub 2017 Jul 20. Review.


Distinct behavioral responses evoked by selective optogenetic stimulation of the major TRPV1+ and MrgD+ subsets of C-fibers.

Beaudry H, Daou I, Ase AR, Ribeiro-da-Silva A, Séguéla P.

Pain. 2017 Dec;158(12):2329-2339. doi: 10.1097/j.pain.0000000000001016.


In vivo optogenetic activation of Nav1.8+ cutaneous nociceptors and their responses to natural stimuli.

Uhelski ML, Bruce DJ, Séguéla P, Wilcox GL, Simone DA.

J Neurophysiol. 2017 Jun 1;117(6):2218-2223. doi: 10.1152/jn.00083.2017. Epub 2017 Mar 15.


Towards the PET radiotracer for p75 neurotrophin receptor: [(11)C]LM11A-24 shows biological activity in vitro, but unfavorable ex vivo and in vivo profile.

Gibon J, Kang MS, Aliaga A, Sharif B, Rosa-Neto P, Séguéla P, Barker PA, Kostikov A.

Bioorg Med Chem. 2016 Oct 1;24(19):4759-4765. doi: 10.1016/j.bmc.2016.08.020. Epub 2016 Aug 13.


The X-linked inhibitor of apoptosis regulates long-term depression and learning rate.

Gibon J, Unsain N, Gamache K, Thomas RA, De Leon A, Johnstone A, Nader K, Séguéla P, Barker PA.

FASEB J. 2016 Sep;30(9):3083-90. doi: 10.1096/fj.201600384R. Epub 2016 May 17.


Optogenetic Silencing of Nav1.8-Positive Afferents Alleviates Inflammatory and Neuropathic Pain.

Daou I, Beaudry H, Ase AR, Wieskopf JS, Ribeiro-da-Silva A, Mogil JS, Séguéla P.

eNeuro. 2016 Mar 16;3(1). pii: ENEURO.0140-15.2016. doi: 10.1523/ENEURO.0140-15.2016. eCollection 2016 Jan-Feb.


HBpF-proBDNF: A New Tool for the Analysis of Pro-Brain Derived Neurotrophic Factor Receptor Signaling and Cell Biology.

Gaub P, de Léon A, Gibon J, Soubannier V, Dorval G, Séguéla P, Barker PA.

PLoS One. 2016 Mar 7;11(3):e0150601. doi: 10.1371/journal.pone.0150601. eCollection 2016.


Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex.

Gibon J, Barker PA, Séguéla P.

Mol Brain. 2016 Mar 1;9:23. doi: 10.1186/s13041-016-0203-9.


Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex.

Cordeiro Matos S, Zhang Z, Séguéla P.

J Neurosci. 2015 Sep 23;35(38):13244-56. doi: 10.1523/JNEUROSCI.0799-15.2015.


proBDNF and p75NTR Control Excitability and Persistent Firing of Cortical Pyramidal Neurons.

Gibon J, Buckley SM, Unsain N, Kaartinen V, Séguéla P, Barker PA.

J Neurosci. 2015 Jul 1;35(26):9741-53. doi: 10.1523/JNEUROSCI.4655-14.2015.


P2Y12 expression and function in alternatively activated human microglia.

Moore CS, Ase AR, Kinsara A, Rao VT, Michell-Robinson M, Leong SY, Butovsky O, Ludwin SK, Séguéla P, Bar-Or A, Antel JP.

Neurol Neuroimmunol Neuroinflamm. 2015 Mar 19;2(2):e80. doi: 10.1212/NXI.0000000000000080. eCollection 2015 Apr. Erratum in: Neurol Neuroimmunol Neuroinflamm. 2015 Jun;2(3):e106.

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