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Items: 1 to 20 of 341

1.

Cell Cycle Analysis of Hematopoietic Stem and Progenitor Cells by Multicolor Flow Cytometry.

Galvin A, Weglarz M, Folz-Donahue K, Handley M, Baum M, Mazzola M, Litwa H, Scadden DT, Silberstein L.

Curr Protoc Cytom. 2018 Oct 18:e50. doi: 10.1002/cpcy.50. [Epub ahead of print]

PMID:
30335223
2.

Biotech leaders call for free press.

Cohen R, Holtzman S, Levin JM, Maraganore JM; Signatories to the Statement.

Nat Biotechnol. 2018 Oct 11;36(10):920-922. doi: 10.1038/nbt.4271. No abstract available.

PMID:
30307914
3.

A point mutation in the Ncr1 signal peptide impairs the development of innate lymphoid cell subsets.

Almeida FF, Tognarelli S, Marçais A, Kueh AJ, Friede ME, Liao Y, Willis SN, Luong K, Faure F, Mercier FE, Galluso J, Firth M, Narni-Mancinelli E, Rais B, Scadden DT, Spallotta F, Weil S, Giannattasio A, Kalensee F, Zöller T, Huntington ND, Schleicher U, Chiocchetti AG, Ugolini S, Herold MJ, Shi W, Koch J, Steinle A, Vivier E, Walzer T, Belz GT, Ullrich E.

Oncoimmunology. 2018 Aug 15;7(10):e1475875. doi: 10.1080/2162402X.2018.1475875. eCollection 2018.

4.

Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer.

Ubellacker JM, Baryawno N, Severe N, DeCristo MJ, Sceneay J, Hutchinson JN, Haider MT, Rhee CS, Qin Y, Gregory WM, Garrido-Castro AC, Holen I, Brown JE, Coleman RE, Scadden DT, McAllister SS.

Cancer Res. 2018 Sep 15;78(18):5300-5314. doi: 10.1158/0008-5472.CAN-18-0548. Epub 2018 Jul 31.

PMID:
30065048
5.

dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments.

Petukhov V, Guo J, Baryawno N, Severe N, Scadden DT, Samsonova MG, Kharchenko PV.

Genome Biol. 2018 Jun 19;19(1):78. doi: 10.1186/s13059-018-1449-6.

6.

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow.

Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA.

Nat Commun. 2018 Jun 18;9(1):2377. doi: 10.1038/s41467-018-04716-5.

7.

Bone marrow drives central nervous system regeneration after radiation injury.

Dietrich J, Baryawno N, Nayyar N, Valtis YK, Yang B, Ly I, Besnard A, Severe N, Gustafsson KU, Andronesi OC, Batchelor TT, Sahay A, Scadden DT.

J Clin Invest. 2018 Jun 1;128(6):2651. doi: 10.1172/JCI121592. Epub 2018 Jun 1. No abstract available.

8.

The NOTCH1/CD44 axis drives pathogenesis in a T cell acute lymphoblastic leukemia model.

García-Peydró M, Fuentes P, Mosquera M, García-León MJ, Alcain J, Rodríguez A, García de Miguel P, Menéndez P, Weijer K, Spits H, Scadden DT, Cuesta-Mateos C, Muñoz-Calleja C, Sánchez-Madrid F, Toribio ML.

J Clin Invest. 2018 Jul 2;128(7):2802-2818. doi: 10.1172/JCI92981. Epub 2018 May 21.

9.

Sipa1 deficiency-induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm.

Xiao P, Dolinska M, Sandhow L, Kondo M, Johansson AS, Bouderlique T, Zhao Y, Li X, Dimitriou M, Rassidakis GZ, Hellström-Lindberg E, Minato N, Walfridsson J, Scadden DT, Sigvardsson M, Qian H.

Blood Adv. 2018 Mar 13;2(5):534-548. doi: 10.1182/bloodadvances.2017013599.

10.

Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell.

Hoggatt J, Singh P, Tate TA, Chou BK, Datari SR, Fukuda S, Liu L, Kharchenko PV, Schajnovitz A, Baryawno N, Mercier FE, Boyer J, Gardner J, Morrow DM, Scadden DT, Pelus LM.

Cell. 2018 Jan 11;172(1-2):191-204.e10. doi: 10.1016/j.cell.2017.11.003. Epub 2017 Dec 7.

PMID:
29224778
11.

Bone marrow drives central nervous system regeneration after radiation injury.

Dietrich J, Baryawno N, Nayyar N, Valtis YK, Yang B, Ly I, Besnard A, Severe N, Gustafsson KU, Andronesi OC, Batchelor TT, Sahay A, Scadden DT.

J Clin Invest. 2018 Jan 2;128(1):281-293. doi: 10.1172/JCI90647. Epub 2017 Dec 4.

12.

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils.

Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ.

Science. 2017 Dec 1;358(6367). pii: eaal5081. doi: 10.1126/science.aal5081.

PMID:
29191879
13.

Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.

Schiroli G, Ferrari S, Conway A, Jacob A, Capo V, Albano L, Plati T, Castiello MC, Sanvito F, Gennery AR, Bovolenta C, Palchaudhuri R, Scadden DT, Holmes MC, Villa A, Sitia G, Lombardo A, Genovese P, Naldini L.

Sci Transl Med. 2017 Oct 11;9(411). pii: eaan0820. doi: 10.1126/scitranslmed.aan0820.

PMID:
29021165
14.

The metabolic regulator mTORC1 controls terminal myeloid differentiation.

Lee PY, Sykes DB, Ameri S, Kalaitzidis D, Charles JF, Nelson-Maney N, Wei K, Cunin P, Morris A, Cardona AE, Root DE, Scadden DT, Nigrovic PA.

Sci Immunol. 2017 May 26;2(11). pii: eaam6641. doi: 10.1126/sciimmunol.aam6641.

PMID:
28763796
15.

ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.

Garrison BS, Rybak AP, Beerman I, Heesters B, Mercier FE, Scadden DT, Bryder D, Baron R, Rossi DJ.

Blood. 2017 Aug 3;130(5):619-624. doi: 10.1182/blood-2016-09-738591. Epub 2017 Jun 14.

16.

Hematopoiesis: Reconciling Historic Controversies about the Niche.

Baryawno N, Severe N, Scadden DT.

Cell Stem Cell. 2017 May 4;20(5):590-592. doi: 10.1016/j.stem.2017.03.025.

17.

Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells.

Kalaitzidis D, Lee D, Efeyan A, Kfoury Y, Nayyar N, Sykes DB, Mercier FE, Papazian A, Baryawno N, Victora GD, Neuberg D, Sabatini DM, Scadden DT.

J Clin Invest. 2017 Apr 3;127(4):1405-1413. doi: 10.1172/JCI89452. Epub 2017 Mar 20.

18.

Written in bone: young bone makes young blood.

Gustafsson K, Scadden DT.

EMBO J. 2017 Apr 3;36(7):831-833. doi: 10.15252/embj.201796634. Epub 2017 Mar 13. No abstract available.

19.

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.

Yu VWC, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT.

Cell. 2017 Feb 23;168(5):944-945. doi: 10.1016/j.cell.2017.02.010. No abstract available.

20.

Shipping mouse bone marrow: Keep it in the bone.

Papazian AE, Kfoury YS, Scadden DT.

Exp Hematol. 2017 May;49:68-72. doi: 10.1016/j.exphem.2016.12.008. Epub 2016 Dec 30.

PMID:
28043821

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