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Items: 8

1.

Functional analysis of rare variants in mismatch repair proteins augments results from computation-based predictive methods.

Arora S, Huwe PJ, Sikder R, Shah M, Browne AJ, Lesh R, Nicolas E, Deshpande S, Hall MJ, Dunbrack RL Jr, Golemis EA.

Cancer Biol Ther. 2017 Jul 3;18(7):519-533. doi: 10.1080/15384047.2017.1326439. Epub 2017 May 11.

2.

Identification of small molecule inhibitors of ERCC1-XPF that inhibit DNA repair and potentiate cisplatin efficacy in cancer cells.

Arora S, Heyza J, Zhang H, Kalman-Maltese V, Tillison K, Floyd AM, Chalfin EM, Bepler G, Patrick SM.

Oncotarget. 2016 Nov 15;7(46):75104-75117. doi: 10.18632/oncotarget.12072.

3.

POLD1: Central mediator of DNA replication and repair, and implication in cancer and other pathologies.

Nicolas E, Golemis EA, Arora S.

Gene. 2016 Sep 15;590(1):128-41. doi: 10.1016/j.gene.2016.06.031. Epub 2016 Jun 16. Review.

4.

Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer.

Nicolas E, Arora S, Zhou Y, Serebriiskii IG, Andrake MD, Handorf ED, Bodian DL, Vockley JG, Dunbrack RL, Ross EA, Egleston BL, Hall MJ, Golemis EA, Giri VN, Daly MB.

Oncotarget. 2015 Nov 24;6(37):39614-33. doi: 10.18632/oncotarget.5554.

5.

Genetic Variants That Predispose to DNA Double-Strand Breaks in Lymphocytes From a Subset of Patients With Familial Colorectal Carcinomas.

Arora S, Yan H, Cho I, Fan HY, Luo B, Gai X, Bodian DL, Vockley JG, Zhou Y, Handorf EA, Egleston BL, Andrake MD, Nicolas E, Serebriiskii IG, Yen TJ, Hall MJ, Golemis EA, Enders GH.

Gastroenterology. 2015 Dec;149(7):1872-1883.e9. doi: 10.1053/j.gastro.2015.08.052. Epub 2015 Sep 5.

6.

A new strategy to ERADicate HER2-positive breast tumors?

Arora S, Golemis EA.

Sci Signal. 2015 May 26;8(378):fs11. doi: 10.1126/scisignal.aac4746.

7.

Reversible cell cycle inhibition and premature aging features imposed by conditional expression of p16Ink4a.

Boquoi A, Arora S, Chen T, Litwin S, Koh J, Enders GH.

Aging Cell. 2015 Feb;14(1):139-47. doi: 10.1111/acel.12279. Epub 2014 Dec 6.

8.

Downregulation of XPF-ERCC1 enhances cisplatin efficacy in cancer cells.

Arora S, Kothandapani A, Tillison K, Kalman-Maltese V, Patrick SM.

DNA Repair (Amst). 2010 Jul 1;9(7):745-53. doi: 10.1016/j.dnarep.2010.03.010. Epub 2010 Apr 24.

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