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Items: 14

1.

Principles of Resistance to Targeted Cancer Therapy: Lessons from Basic and Translational Cancer Biology.

Sabnis AJ, Bivona TG.

Trends Mol Med. 2019 Mar;25(3):185-197. doi: 10.1016/j.molmed.2018.12.009. Epub 2019 Jan 24. Review.

PMID:
30686761
2.

Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway.

Bugaj LJ, Sabnis AJ, Mitchell A, Garbarino JE, Toettcher JE, Bivona TG, Lim WA.

Science. 2018 Aug 31;361(6405). pii: eaao3048. doi: 10.1126/science.aao3048.

3.

Compensatory increases of select proteostasis networks after Hsp70 inhibition in cancer cells.

Sannino S, Guerriero CJ, Sabnis AJ, Stolz DB, Wallace CT, Wipf P, Watkins SC, Bivona TG, Brodsky JL.

J Cell Sci. 2018 Sep 5;131(17). pii: jcs217760. doi: 10.1242/jcs.217760.

4.

EWSR1-NFATC2 gene fusion in a soft tissue tumor with epithelioid round cell morphology and abundant stroma: a case report and review of the literature.

Cohen JN, Sabnis AJ, Krings G, Cho SJ, Horvai AE, Davis JL.

Hum Pathol. 2018 Nov;81:281-290. doi: 10.1016/j.humpath.2018.03.020. Epub 2018 Apr 4.

PMID:
29626598
5.

Pulmonary veno-occlusive disease in a pediatric hematopoietic stem cell transplant patient: a cautionary tale.

Zinter MS, Melton A, Sabnis AJ, Dvorak CC, Elicker BM, Nawaytou HM, Kameny RJ, Fineman JR.

Leuk Lymphoma. 2018 Jun;59(6):1494-1497. doi: 10.1080/10428194.2017.1382697. Epub 2017 Sep 28. No abstract available.

PMID:
28958195
6.

Reducing Second Gram-Negative Antibiotic Therapy on Pediatric Oncology and Hematopoietic Stem Cell Transplantation Services.

Wattier RL, Levy ER, Sabnis AJ, Dvorak CC, Auerbach AD.

Infect Control Hosp Epidemiol. 2017 Sep;38(9):1039-1047. doi: 10.1017/ice.2017.118. Epub 2017 Jul 31.

PMID:
28758610
7.

HSP70 dependence in rhabdomyosarcoma: Seed or soil?

Sabnis AJ, Bivona TG.

Cell Cycle. 2017 Jan 17;16(2):147-148. doi: 10.1080/15384101.2016.1237168. Epub 2016 Sep 29. No abstract available.

8.

Combined chemical-genetic approach identifies cytosolic HSP70 dependence in rhabdomyosarcoma.

Sabnis AJ, Guerriero CJ, Olivas V, Sayana A, Shue J, Flanagan J, Asthana S, Paton AW, Paton JC, Gestwicki JE, Walter P, Weissman JS, Wipf P, Brodsky JL, Bivona TG.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):9015-20. doi: 10.1073/pnas.1603883113. Epub 2016 Jul 22.

9.

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies.

Lin L, Sabnis AJ, Chan E, Olivas V, Cade L, Pazarentzos E, Asthana S, Neel D, Yan JJ, Lu X, Pham L, Wang MM, Karachaliou N, Cao MG, Manzano JL, Ramirez JL, Torres JM, Buttitta F, Rudin CM, Collisson EA, Algazi A, Robinson E, Osman I, Muñoz-Couselo E, Cortes J, Frederick DT, Cooper ZA, McMahon M, Marchetti A, Rosell R, Flaherty KT, Wargo JA, Bivona TG.

Nat Genet. 2015 Mar;47(3):250-6. doi: 10.1038/ng.3218. Epub 2015 Feb 9.

10.

Activating mutations cluster in the "molecular brake" regions of protein kinases and do not associate with conserved or catalytic residues.

Molina-Vila MA, Nabau-Moretó N, Tornador C, Sabnis AJ, Rosell R, Estivill X, Bivona TG, Marino-Buslje C.

Hum Mutat. 2014 Mar;35(3):318-28. doi: 10.1002/humu.22493. Epub 2014 Jan 8.

PMID:
24323975
11.

FGFR fusions in the driver's seat.

Sabnis AJ, Bivona TG.

Cancer Discov. 2013 Jun;3(6):607-9. doi: 10.1158/2159-8290.CD-13-0185.

12.

JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.

Santaguida M, Schepers K, King B, Sabnis AJ, Forsberg EC, Attema JL, Braun BS, Passegué E.

Cancer Cell. 2009 Apr 7;15(4):341-52. doi: 10.1016/j.ccr.2009.02.016.

13.

Oncogenic Kras initiates leukemia in hematopoietic stem cells.

Sabnis AJ, Cheung LS, Dail M, Kang HC, Santaguida M, Hermiston ML, Passegué E, Shannon K, Braun BS.

PLoS Biol. 2009 Mar 17;7(3):e59. doi: 10.1371/journal.pbio.1000059.

14.

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects.

McGowan KA, Li JZ, Park CY, Beaudry V, Tabor HK, Sabnis AJ, Zhang W, Fuchs H, de Angelis MH, Myers RM, Attardi LD, Barsh GS.

Nat Genet. 2008 Aug;40(8):963-70. doi: 10.1038/ng.188. Epub 2008 Jul 20.

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