Format

Send to

Choose Destination

See 1 citation found by title matching your search:

Mol Aspects Med. 2013 Apr-Jun;34(2-3):236-51. doi: 10.1016/j.mam.2012.05.001.

SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/Hexchangers.

Author information

1
Departments of Medicine and Physiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States. mdonowit@jhmi.edu

Abstract

This brief review of the human Na/H exchanger gene family introduces a new classification with three subgroups to the SLC9 gene family. Progress in the structure and function of this gene family is reviewed with structure based on homology to the bacterial Na/H exchanger NhaA. Human diseases which result from genetic abnormalities of the SLC9 family are discussed although the exact role of these transporters in causing any disease is not established, other than poorly functioning NHE3 in congenital Na diarrhea.

PMID:
23506868
PMCID:
PMC3724465
DOI:
10.1016/j.mam.2012.05.001
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center