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Mol Aspects Med. 2013 Apr-Jun;34(2-3):350-9. doi: 10.1016/j.mam.2012.05.004.

SLC17: a functionally diverse family of organic anion transporters.

Author information

1
Neurogenetics Division Department of Neurology and Neurological Sciences, Stanford University School of Medicine, P211 MSLS, 1201 Welch Road, Stanford, CA 94305, USA. rjreimer@stanford.edu

Abstract

Molecular studies have determined that the SLC17 transporters, a family of nine proteins initially implicated in phosphate transport, mediate the transport of organic anions. While their role in phosphate transport remains uncertain, it is now clear that the transport of organic anions facilitated by this family of proteins is involved in diverse processes ranging from the vesicular storage of the neurotransmitters, to urate metabolism, to the degradation and metabolism of glycoproteins.

PMID:
23506876
PMCID:
PMC3927456
DOI:
10.1016/j.mam.2012.05.004
[Indexed for MEDLINE]
Free PMC Article

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