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J Exp Stroke Transl Med. 2010 Jan 1;3(1):19-27.

Fundamentals of clinical trial design.

Author information

1
Department of Statistics, Harvard University, Boston, MA.

Abstract

Most errors in clinical trials are a result of poor planning. Fancy statistical methods cannot rescue design flaws. Thus careful planning with clear foresight is crucial. Issues in trial conduct and analyses should be anticipated during trial design and thoughtfully addressed. Fundamental clinical trial design issues are discussed.

PMID:
21533012
PMCID:
PMC3083073

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