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Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth.
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS. Ensan S, et al. Among authors: roufaiel m. Nat Immunol. 2016 Feb;17(2):159-68. doi: 10.1038/ni.3343. Epub 2015 Dec 7. Nat Immunol. 2016. PMID: 26642357
A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis.
Armstrong SM, Sugiyama MG, Fung KY, Gao Y, Wang C, Levy AS, Azizi P, Roufaiel M, Zhu SN, Neculai D, Yin C, Bolz SS, Seidah NG, Cybulsky MI, Heit B, Lee WL. Armstrong SM, et al. Among authors: roufaiel m. Cardiovasc Res. 2015 Nov 1;108(2):268-77. doi: 10.1093/cvr/cvv218. Epub 2015 Sep 2. Cardiovasc Res. 2015. PMID: 26334034 Free PMC article.
CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.
Roufaiel M, Gracey E, Siu A, Zhu SN, Lau A, Ibrahim H, Althagafi M, Tai K, Hyduk SJ, Cybulsky KO, Ensan S, Li A, Besla R, Becker HM, Xiao H, Luther SA, Inman RD, Robbins CS, Jongstra-Bilen J, Cybulsky MI. Roufaiel M, et al. Nat Immunol. 2016 Nov;17(11):1263-1272. doi: 10.1038/ni.3564. Epub 2016 Sep 26. Nat Immunol. 2016. PMID: 27668800
Erratum: CCL19-CCR7-dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima.
Roufaiel M, Gracey E, Siu A, Zhu SN, Lau A, Ibrahim H, Althagafi M, Tai K, Hyduk SJ, Cybulsky KO, Ensan S, Li A, Besla R, Becker HM, Xiao H, Luther SA, Inman RD, Robbins CS, Jongstra-Bilen J, Cybulsky MI. Roufaiel M, et al. Nat Immunol. 2017 May 18;18(6):705. doi: 10.1038/ni0617-705d. Nat Immunol. 2017. PMID: 28518165 No abstract available.