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Items: 1 to 20 of 147


Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice.

Gimpfl M, Rozman J, Dahlhoff M, Kübeck R, Blutke A, Rathkolb B, Klingenspor M, Hrabě de Angelis M, Öner-Sieben S, Seibt A, Roscher AA, Wolf E, Ensenauer R.

Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1605-1614. doi: 10.1016/j.bbadis.2017.02.021. Epub 2017 Feb 21.


The leukemogenic fusion gene MLL-AF9 alters microRNA expression pattern and inhibits monoblastic differentiation via miR-511 repression.

Fleischmann KK, Pagel P, von Frowein J, Magg T, Roscher AA, Schmid I.

J Exp Clin Cancer Res. 2016 Jan 13;35:9. doi: 10.1186/s13046-016-0283-5.


Obese Nondiabetic Pregnancies and High Maternal Glycated Hemoglobin at Delivery as an Indicator of Offspring and Maternal Postpartum Risks: The Prospective PEACHES Mother-Child Cohort.

Ensenauer R, Brandlhuber L, Burgmann M, Sobotzki C, Zwafink C, Anzill S, Holdt L, Teupser D, Hasbargen U, Netz H, Roscher AA, von Kries R.

Clin Chem. 2015 Nov;61(11):1381-90. doi: 10.1373/clinchem.2015.242206. Epub 2015 Aug 11.


RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes.

Fleischmann KK, Pagel P, Schmid I, Roscher AA.

Mol Cancer. 2014 Feb 11;13:27. doi: 10.1186/1476-4598-13-27.


Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring.

Dahlhoff M, Pfister S, Blutke A, Rozman J, Klingenspor M, Deutsch MJ, Rathkolb B, Fink B, Gimpfl M, Hrabě de Angelis M, Roscher AA, Wolf E, Ensenauer R.

Biochim Biophys Acta. 2014 Feb;1842(2):304-17. doi: 10.1016/j.bbadis.2013.11.021. Epub 2013 Nov 23.


Digital image analysis approach for lipid droplet size quantitation of Oil Red O-stained cultured cells.

Deutsch MJ, Schriever SC, Roscher AA, Ensenauer R.

Anal Biochem. 2014 Jan 15;445:87-9. doi: 10.1016/j.ab.2013.10.001. Epub 2013 Oct 10.


Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism.

Schriever SC, Deutsch MJ, Adamski J, Roscher AA, Ensenauer R.

J Nutr Biochem. 2013 May;24(5):824-31. doi: 10.1016/j.jnutbio.2012.04.018. Epub 2012 Aug 13.


Changing metabolic signatures of amino acids and lipids during the prediabetic period in a pig model with impaired incretin function and reduced β-cell mass.

Renner S, Römisch-Margl W, Prehn C, Krebs S, Adamski J, Göke B, Blum H, Suhre K, Roscher AA, Wolf E.

Diabetes. 2012 Aug;61(8):2166-75. doi: 10.2337/db11-1133. Epub 2012 Apr 9.


In situ assay of fatty acid β-oxidation by metabolite profiling following permeabilization of cell membranes.

Ensenauer R, Fingerhut R, Schriever SC, Fink B, Becker M, Sellerer NC, Pagel P, Kirschner A, Dame T, Olgemöller B, Röschinger W, Roscher AA.

J Lipid Res. 2012 May;53(5):1012-20. doi: 10.1194/jlr.D022608. Epub 2012 Feb 16.


Efficient and gentle siRNA delivery by magnetofection.

Ensenauer R, Hartl D, Vockley J, Roscher AA, Fuchs U.

Biotech Histochem. 2011 Aug;86(4):226-31. doi: 10.3109/10520291003675485. Epub 2010 Mar 18.


Pahenu1 is a mouse model for tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency and promotes analysis of the pharmacological chaperone mechanism in vivo.

Gersting SW, Lagler FB, Eichinger A, Kemter KF, Danecka MK, Messing DD, Staudigl M, Domdey KA, Zsifkovits C, Fingerhut R, Glossmann H, Roscher AA, Muntau AC.

Hum Mol Genet. 2010 May 15;19(10):2039-49. doi: 10.1093/hmg/ddq085. Epub 2010 Feb 23.


Dissection of biochemical borderline phenotypes in carriers and genetic variants of medium-chain acyl-CoA dehyrogenase deficiency: implications for newborn screening [corrected].

Maier EM, Pongratz J, Muntau AC, Liebl B, Nennstiel-Ratzel U, Busch U, Fingerhut R, Olgemöller B, Roscher AA, Röschinger W.

Clin Genet. 2009 Aug;76(2):179-87. doi: 10.1111/j.1399-0004.2009.01217.x. Erratum in: Clin Genet. 2010 Mar;77(3):304.


Stability of acylcarnitines and free carnitine in dried blood samples: implications for retrospective diagnosis of inborn errors of metabolism and neonatal screening for carnitine transporter deficiency.

Fingerhut R, Ensenauer R, Röschinger W, Arnecke R, Olgemöller B, Roscher AA.

Anal Chem. 2009 May 1;81(9):3571-5. doi: 10.1021/ac8022235.


My 39 years with the International College of Surgeons.

Roscher AA.

Int Surg. 2008 Nov-Dec;93(6):309-13. No abstract available.


X-linked adrenoleukodystrophy phenotype is independent of ABCD2 genotype.

Maier EM, Mayerhofer PU, Asheuer M, Köhler W, Rothe M, Muntau AC, Roscher AA, Holzinger A, Aubourg P, Berger J.

Biochem Biophys Res Commun. 2008 Dec 5;377(1):176-80. doi: 10.1016/j.bbrc.2008.09.092. Epub 2008 Oct 1.


Loss of function in phenylketonuria is caused by impaired molecular motions and conformational instability.

Gersting SW, Kemter KF, Staudigl M, Messing DD, Danecka MK, Lagler FB, Sommerhoff CP, Roscher AA, Muntau AC.

Am J Hum Genet. 2008 Jul;83(1):5-17. doi: 10.1016/j.ajhg.2008.05.013. Epub 2008 Jun 5.


Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease.

Hartl D, Latzin P, Hordijk P, Marcos V, Rudolph C, Woischnik M, Krauss-Etschmann S, Koller B, Reinhardt D, Roscher AA, Roos D, Griese M.

Nat Med. 2007 Dec;13(12):1423-30. Epub 2007 Dec 2.


Newborn screening for 3-methylcrotonyl-CoA carboxylase deficiency: population heterogeneity of MCCA and MCCB mutations and impact on risk assessment.

Stadler SC, Polanetz R, Maier EM, Heidenreich SC, Niederer B, Mayerhofer PU, Lagler F, Koch HG, Santer R, Fletcher JM, Ranieri E, Das AM, Spiekerkötter U, Schwab KO, Pötzsch S, Marquardt I, Hennermann JB, Knerr I, Mercimek-Mahmutoglu S, Kohlschmidt N, Liebl B, Fingerhut R, Olgemöller B, Muntau AC, Roscher AA, Röschinger W.

Hum Mutat. 2006 Aug;27(8):748-59.


Disease manifestations and X inactivation in heterozygous females with Fabry disease.

Maier EM, Osterrieder S, Whybra C, Ries M, Gal A, Beck M, Roscher AA, Muntau AC.

Acta Paediatr Suppl. 2006 Apr;95(451):30-8.


Role of Pex19p in the targeting of PMP70 to peroxisome.

Kashiwayama Y, Asahina K, Shibata H, Morita M, Muntau AC, Roscher AA, Wanders RJ, Shimozawa N, Sakaguchi M, Kato H, Imanaka T.

Biochim Biophys Acta. 2005 Dec 15;1746(2):116-28. Epub 2005 Nov 14.

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