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Items: 1 to 20 of 49

1.

AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation.

Ha Y, Liu W, Liu H, Zhu S, Xia F, Gerson JE, Azhar NA, Tilton RG, Motamedi M, Kayed R, Zhang W.

Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4670-4682. doi: 10.1167/iovs.18-24427.

2.

Sirt6 deficiency impairs corneal epithelial wound healing.

Hu X, Zhu S, Liu R, Miller JD, Merkley K, Tilton RG, Liu H.

Aging (Albany NY). 2018 Aug 2;10(8):1932-1946. doi: 10.18632/aging.101513.

3.

Deletion of NF-κB/RelA in Angiotensin II-Sensitive Mesenchymal Cells Blocks Aortic Vascular Inflammation and Abdominal Aortic Aneurysm Formation.

Ijaz T, Sun H, Pinchuk IV, Milewicz DM, Tilton RG, Brasier AR.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1881-1890. doi: 10.1161/ATVBAHA.117.309863. Epub 2017 Aug 17.

4.

Sirt6 deficiency results in progression of glomerular injury in the kidney.

Huang W, Liu H, Zhu S, Woodson M, Liu R, Tilton RG, Miller JD, Zhang W.

Aging (Albany NY). 2017 Mar 28;9(3):1069-1083. doi: 10.18632/aging.101214.

5.

Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation.

Ijaz T, Jamaluddin M, Zhao Y, Zhang Y, Jay J, Finnerty CC, Herndon DN, Tilton RG, Brasier AR.

Cell Death Dis. 2017 Feb 9;8(2):e2606. doi: 10.1038/cddis.2016.434.

6.

Glucocorticoids increase skeletal muscle NF-κB inducing kinase (NIK): links to muscle atrophy.

Fry CS, Nayeem SZ, Dillon EL, Sarkar PS, Tumurbaatar B, Urban RJ, Wright TJ, Sheffield-Moore M, Tilton RG, Choudhary S.

Physiol Rep. 2016 Nov;4(21). pii: e13014. Epub 2016 Nov 14.

7.

Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles.

Ijaz T, Wakamiya M, Sun H, Recinos A 3rd, Tilton RG, Brasier AR.

BMC Dev Biol. 2016 Sep 23;16(1):32.

8.

Cytokine amplification and macrophage effector functions in aortic inflammation and abdominal aortic aneurysm formation.

Ijaz T, Tilton RG, Brasier AR.

J Thorac Dis. 2016 Aug;8(8):E746-54. doi: 10.21037/jtd.2016.06.37.

9.

Posttranslational modification of Sirt6 activity by peroxynitrite.

Hu S, Liu H, Ha Y, Luo X, Motamedi M, Gupta MP, Ma JX, Tilton RG, Zhang W.

Free Radic Biol Med. 2015 Feb;79:176-85. doi: 10.1016/j.freeradbiomed.2014.11.011. Epub 2014 Dec 2.

10.

Oxidative stress induces endothelial cell senescence via downregulation of Sirt6.

Liu R, Liu H, Ha Y, Tilton RG, Zhang W.

Biomed Res Int. 2014;2014:902842. doi: 10.1155/2014/902842. Epub 2014 Aug 5.

11.

Nicotine accelerates diabetes-induced retinal changes.

Boretsky A, Gupta P, Tirgan N, Liu R, Godley BF, Zhang W, Tilton RG, Motamedi M.

Curr Eye Res. 2015 Apr;40(4):368-77. doi: 10.3109/02713683.2014.924147. Epub 2014 Jun 9.

12.

IL-6 regulates extracellular matrix remodeling associated with aortic dilation in a fibrillin-1 hypomorphic mgR/mgR mouse model of severe Marfan syndrome.

Ju X, Ijaz T, Sun H, Lejeune W, Vargas G, Shilagard T, Recinos A 3rd, Milewicz DM, Brasier AR, Tilton RG.

J Am Heart Assoc. 2014 Jan 21;3(1):e000476. doi: 10.1161/JAHA.113.000476.

13.

TWEAK/Fn14 pathway is a novel mediator of retinal neovascularization.

Ameri H, Liu H, Liu R, Ha Y, Paulucci-Holthauzen AA, Hu S, Motamedi M, Godley BF, Tilton RG, Zhang W.

Invest Ophthalmol Vis Sci. 2014 Feb 10;55(2):801-13. doi: 10.1167/iovs.13-12812.

14.

Klotho ameliorates chemically induced endoplasmic reticulum (ER) stress signaling.

Banerjee S, Zhao Y, Sarkar PS, Rosenblatt KP, Tilton RG, Choudhary S.

Cell Physiol Biochem. 2013;31(4-5):659-72. doi: 10.1159/000350085. Epub 2013 May 8.

15.

Interleukin-6-signal transducer and activator of transcription-3 signaling mediates aortic dissections induced by angiotensin II via the T-helper lymphocyte 17-interleukin 17 axis in C57BL/6 mice.

Ju X, Ijaz T, Sun H, Ray S, Lejeune W, Lee C, Recinos A 3rd, Guo DC, Milewicz DM, Tilton RG, Brasier AR.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1612-21. doi: 10.1161/ATVBAHA.112.301049. Epub 2013 May 16.

16.

Nicotine exposure exacerbates development of cataracts in a type 1 diabetic rat model.

Tirgan N, Kulp GA, Gupta P, Boretsky A, Wiraszka TA, Godley B, Tilton RG, Motamedi M.

Exp Diabetes Res. 2012;2012:349320. doi: 10.1155/2012/349320. Epub 2012 Sep 20.

17.

Proteomics and systems biology for understanding diabetic nephropathy.

Starkey JM, Tilton RG.

J Cardiovasc Transl Res. 2012 Aug;5(4):479-90. doi: 10.1007/s12265-012-9372-9. Epub 2012 May 12. Review.

18.

Hyperglycemia exacerbates burn-induced liver inflammation via noncanonical nuclear factor-κB pathway activation.

Kulp GA, Tilton RG, Herndon DN, Jeschke MG.

Mol Med. 2012 Sep 7;18:948-56. doi: 10.2119/molmed.2011.00357. Erratum in: Mol Med. 2012;18: doi/10.2119/molmed.2012.00007.erratum.

19.

NF-κB-inducing kinase increases renal tubule epithelial inflammation associated with diabetes.

Zhao Y, Banerjee S, LeJeune WS, Choudhary S, Tilton RG.

Exp Diabetes Res. 2011;2011:192564. doi: 10.1155/2011/192564. Epub 2011 Aug 18.

20.

NF-kappaB-inducing kinase (NIK) mediates skeletal muscle insulin resistance: blockade by adiponectin.

Choudhary S, Sinha S, Zhao Y, Banerjee S, Sathyanarayana P, Shahani S, Sherman V, Tilton RG, Bajaj M.

Endocrinology. 2011 Oct;152(10):3622-7. doi: 10.1210/en.2011-1343. Epub 2011 Aug 16.

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