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Role of spinal cyclooxygenase in human postoperative and chronic pain.
Anesthesiology. 2010.
PMID: 20395820
Free PMC article.
Clinical Trial.
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Role of spinal cyclooxygenase in human postoperative and chronic pain.
Eisenach JC, Curry R, Rauck R, Pan P, Yaksh TL.
Eisenach JC, et al.
Anesthesiology. 2010 May;112(5):1225-33. doi: 10.1097/ALN.0b013e3181d94dc0.
Anesthesiology. 2010.
PMID: 20395820
Free PMC article.
Clinical Trial.
BACKGROUND: Nonsteroidal antiinflammatory drugs are commonly used to treat postoperative and chronic pain. Animal studies suggest that these drugs act, in part, by blocking prostaglandin production in the spinal cord. ...Under the conditions of these s …
BACKGROUND: Nonsteroidal antiinflammatory drugs are commonly used to treat postoperative and chronic pain. Animal studi …
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The role of the spinal cyclooxygenase (COX) for incisional pain in rats at different developmental stages.
Segelcke D, Reichl S, Neuffer S, Zapp S, Rüther T, Evers D, Zahn PK, Pogatzki-Zahn EM.
Segelcke D, et al.
Eur J Pain. 2020 Feb;24(2):312-324. doi: 10.1002/ejp.1487. Epub 2019 Oct 21.
Eur J Pain. 2020.
PMID: 31566273
BACKGROUND: Cyclooxygenase enzymes (COX)-1 and COX-2 are important targets for pain relief after surgery, but the spinal contribution of both isoforms is still unclear, e.g., from a developmental point of view. ...SIGNIFICANCE: Postoperative pain …
BACKGROUND: Cyclooxygenase enzymes (COX)-1 and COX-2 are important targets for pain relief after surgery, but the spinal …
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