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2012 | 2 |
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Page 1
β-Lactamase inhibition by 7-alkylidenecephalosporin sulfones: allylic transposition and formation of an unprecedented stabilized acyl-enzyme.
J Am Chem Soc. 2013 Dec 11;135(49):18358-69. doi: 10.1021/ja403598g. Epub 2013 Dec 3.
J Am Chem Soc. 2013.
PMID: 24219313
Free PMC article.
Design and exploration of novel boronic acid inhibitors reveals important interactions with a clavulanic acid-resistant sulfhydryl-variable (SHV) β-lactamase.
Winkler ML, Rodkey EA, Taracila MA, Drawz SM, Bethel CR, Papp-Wallace KM, Smith KM, Xu Y, Dwulit-Smith JR, Romagnoli C, Caselli E, Prati F, van den Akker F, Bonomo RA.
Winkler ML, et al. Among authors: rodkey ea.
J Med Chem. 2013 Feb 14;56(3):1084-97. doi: 10.1021/jm301490d. Epub 2013 Feb 4.
J Med Chem. 2013.
PMID: 23252553
Free PMC article.
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Racial/ethnic differences in survival among elderly patients with a primary glioblastoma.
Barnholtz-Sloan JS, Maldonado JL, Williams VL, Curry WT, Rodkey EA, Barker FG 2nd, Sloan AE.
Barnholtz-Sloan JS, et al. Among authors: rodkey ea.
J Neurooncol. 2007 Nov;85(2):171-80. doi: 10.1007/s11060-007-9405-4. Epub 2007 May 26.
J Neurooncol. 2007.
PMID: 17530174
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Detecting a quasi-stable imine species on the reaction pathway of SHV-1 β-lactamase and 6β-(hydroxymethyl)penicillanic acid sulfone.
Che T, Rodkey EA, Bethel CR, Shanmugam S, Ding Z, Pusztai-Carey M, Nottingham M, Chai W, Buynak JD, Bonomo RA, van den Akker F, Carey PR.
Che T, et al. Among authors: rodkey ea.
Biochemistry. 2015 Jan 27;54(3):734-43. doi: 10.1021/bi501197t. Epub 2015 Jan 8.
Biochemistry. 2015.
PMID: 25536850
Free PMC article.
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Penam sulfones and β-lactamase inhibition: SA2-13 and the importance of the C2 side chain length and composition.
Rodkey EA, Winkler ML, Bethel CR, Pagadala SR, Buynak JD, Bonomo RA, van den Akker F.
Rodkey EA, et al.
PLoS One. 2014 Jan 16;9(1):e85892. doi: 10.1371/journal.pone.0085892. eCollection 2014.
PLoS One. 2014.
PMID: 24454944
Free PMC article.
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Crystal structure of a preacylation complex of the β-lactamase inhibitor sulbactam bound to a sulfenamide bond-containing thiol-β-lactamase.
Rodkey EA, Drawz SM, Sampson JM, Bethel CR, Bonomo RA, van den Akker F.
Rodkey EA, et al.
J Am Chem Soc. 2012 Oct 10;134(40):16798-804. doi: 10.1021/ja3073676. Epub 2012 Sep 26.
J Am Chem Soc. 2012.
PMID: 22974281
Free PMC article.
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The importance of the trans-enamine intermediate as a β-lactamase inhibition strategy probed in inhibitor-resistant SHV β-lactamase variants.
Ke W, Rodkey EA, Sampson JM, Skalweit MJ, Sheri A, Pagadala SR, Nottingham MD, Buynak JD, Bonomo RA, van den Akker F.
Ke W, et al. Among authors: rodkey ea.
ChemMedChem. 2012 Jun;7(6):1002-8. doi: 10.1002/cmdc.201200006. Epub 2012 Mar 21.
ChemMedChem. 2012.
PMID: 22438274
Free PMC article.
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