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Items: 1 to 20 of 140

1.

In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation.

Andergassen D, Smith ZD, Lewandowski JP, Gerhardinger C, Meissner A, Rinn JL.

Elife. 2019 Nov 18;8. pii: e47214. doi: 10.7554/eLife.47214.

2.

The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.

Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL.

Nat Commun. 2019 Nov 13;10(1):5137. doi: 10.1038/s41467-019-12970-4.

3.

Linking long noncoding RNA to drug resistance.

Smallegan MJ, Rinn JL.

Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):21963-21965. doi: 10.1073/pnas.1915690116. Epub 2019 Oct 10. No abstract available.

PMID:
31601736
4.

RNA-seq as a tool for evaluating human embryo competence.

Groff AF, Resetkova N, DiDomenico F, Sakkas D, Penzias A, Rinn JL, Eggan K.

Genome Res. 2019 Oct;29(10):1705-1718. doi: 10.1101/gr.252981.119. Epub 2019 Sep 23.

5.

Single-cell imaging reveals unexpected heterogeneity of telomerase reverse transcriptase expression across human cancer cell lines.

Rowland TJ, Dumbović G, Hass EP, Rinn JL, Cech TR.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18488-18497. doi: 10.1073/pnas.1908275116. Epub 2019 Aug 26.

PMID:
31451652
6.

Differential contribution of steady-state RNA and active transcription in chromatin organization.

Barutcu AR, Blencowe BJ, Rinn JL.

EMBO Rep. 2019 Oct 4;20(10):e48068. doi: 10.15252/embr.201948068. Epub 2019 Aug 26.

7.

Illuminating Genomic Dark Matter with RNA Imaging.

Raj A, Rinn JL.

Cold Spring Harb Perspect Biol. 2019 May 1;11(5). pii: a032094. doi: 10.1101/cshperspect.a032094. Review.

PMID:
31043413
8.

High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity.

Mattioli K, Volders PJ, Gerhardinger C, Lee JC, Maass PG, Melé M, Rinn JL.

Genome Res. 2019 Mar;29(3):344-355. doi: 10.1101/gr.242222.118. Epub 2019 Jan 25.

9.

Enhancers in the Peril lincRNA locus regulate distant but not local genes.

Groff AF, Barutcu AR, Lewandowski JP, Rinn JL.

Genome Biol. 2018 Dec 11;19(1):219. doi: 10.1186/s13059-018-1589-8.

10.

Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2.

Elling R, Robinson EK, Shapleigh B, Liapis SC, Covarrubias S, Katzman S, Groff AF, Jiang Z, Agarwal S, Motwani M, Chan J, Sharma S, Hennessy EJ, FitzGerald GA, McManus MT, Rinn JL, Fitzgerald KA, Carpenter S.

Cell Rep. 2018 Nov 6;25(6):1511-1524.e6. doi: 10.1016/j.celrep.2018.10.027.

11.

Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome.

Cacchiarelli D, Qiu X, Srivatsan S, Manfredi A, Ziller M, Overbey E, Grimaldi A, Grimsby J, Pokharel P, Livak KJ, Li S, Meissner A, Mikkelsen TS, Rinn JL, Trapnell C.

Cell Syst. 2018 Sep 26;7(3):258-268.e3. doi: 10.1016/j.cels.2018.07.006. Epub 2018 Sep 5.

12.

Interchromosomal interactions: A genomic love story of kissing chromosomes.

Maass PG, Barutcu AR, Rinn JL.

J Cell Biol. 2019 Jan 7;218(1):27-38. doi: 10.1083/jcb.201806052. Epub 2018 Sep 4. Review.

13.

Reorganization of inter-chromosomal interactions in the 2q37-deletion syndrome.

Maass PG, Weise A, Rittscher K, Lichtenwald J, Barutcu AR, Liehr T, Aydin A, Wefeld-Neuenfeld Y, Pölsler L, Tinschert S, Rinn JL, Luft FC, Bähring S.

EMBO J. 2018 Aug 1;37(15). pii: e96257. doi: 10.15252/embj.201696257. Epub 2018 Jun 19.

14.

An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.

Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP.

Cell. 2018 Apr 19;173(3):649-664.e20. doi: 10.1016/j.cell.2018.03.052.

15.

A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus.

Barutcu AR, Maass PG, Lewandowski JP, Weiner CL, Rinn JL.

Nat Commun. 2018 Apr 13;9(1):1444. doi: 10.1038/s41467-018-03614-0.

16.

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, Giorgi FM, Califano A, Rinn JL, Meissner A, Hirschhorn JN, Daley GQ.

Cell Stem Cell. 2018 Apr 5;22(4):575-588.e7. doi: 10.1016/j.stem.2018.03.012.

17.

Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C.

Maass PG, Barutcu AR, Weiner CL, Rinn JL.

Mol Cell. 2018 Apr 5;70(1):188-189. doi: 10.1016/j.molcel.2018.03.021. No abstract available.

18.

Dynamic changes during the treatment of pancreatic cancer.

Wolff RA, Wang-Gillam A, Alvarez H, Tiriac H, Engle D, Hou S, Groff AF, San Lucas A, Bernard V, Allenson K, Castillo J, Kim D, Mulu F, Huang J, Stephens B, Wistuba II, Katz M, Varadhachary G, Park Y, Hicks J, Chinnaiyan A, Scampavia L, Spicer T, Gerhardinger C, Maitra A, Tuveson D, Rinn J, Lizee G, Yee C, Levine AJ.

Oncotarget. 2018 Feb 13;9(19):14764-14790. doi: 10.18632/oncotarget.24483. eCollection 2018 Mar 13.

19.

Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C.

Maass PG, Barutcu AR, Weiner CL, Rinn JL.

Mol Cell. 2018 Mar 15;69(6):1039-1045.e3. doi: 10.1016/j.molcel.2018.02.007. Epub 2018 Mar 8. Erratum in: Mol Cell. 2018 Apr 5;70(1):188-189.

20.

Genetic determinants and epigenetic effects of pioneer-factor occupancy.

Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A.

Nat Genet. 2018 Feb;50(2):250-258. doi: 10.1038/s41588-017-0034-3. Epub 2018 Jan 22.

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