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Scand Cardiovasc J. 2014 Oct;48(5):284-90. doi: 10.3109/14017431.2014.942873. Epub 2014 Aug 6.

Reproducibility of grayscale and radiofrequency IVUS data acquisition in stented coronary arteries.

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1
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology , Trondheim , Norway.

Abstract

OBJECTIVES:

Variability in data acquisition from intervened coronary arteries could represent a source of error that has implications for the design of serial stent studies. We assessed inter-pullback reproducibility of volumetric grayscale and radiofrequency intravascular ultrasound (IVUS) data in stented coronary arteries.

DESIGN:

Fifteen patients with coronary artery lesions treated with stent implantation were included and examined with two separate pullbacks using the Eagle Eye Gold-phased array 20 MHz IVUS catheter (Volcano). The arteries were divided into five segments, giving a total of 150 sub-segments for analyses. Matching of frames was performed using landmarks that were clearly visible in coronary angiography and intravascular pullbacks. Data were analyzed off-line at an independent Corelab.

RESULTS:

The inter-pullback reproducibility of geometrical data was very good for non-stented segments with relative differences less than 5% between pullbacks for lumen-, vessel-, and plaque volumes. For stented segments reproducibility was poorer with relative differences between pullbacks in the range of 5-10%. The inter-pullback reproducibility of compositional data demonstrated large standard deviations of relative differences, indicating a weaker agreement.

CONCLUSIONS:

Agreements between pullbacks were weaker in stented than those in non-stented segments. Based on our data, future longitudinal IVUS studies in intervened vessels should account for a variability of 5-10% attributed to the acquisition of images.

KEYWORDS:

IVUS; coronary stent; reproducibility

PMID:
25014156
DOI:
10.3109/14017431.2014.942873
[Indexed for MEDLINE]

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