Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 30


High Frequencies of Caspase-3 Expressing Mycobacterium tuberculosis-Specific CD4+ T Cells Are Associated With Active Tuberculosis.

Adekambi T, Ibegbu CC, Cagle S, Ray SM, Rengarajan J.

Front Immunol. 2018 Jun 25;9:1481. doi: 10.3389/fimmu.2018.01481. eCollection 2018.


A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection.

Whatney WE, Gandhi NR, Lindestam Arlehamn CS, Nizam A, Wu H, Quezada MJ, Campbell A, Allana S, Kabongo MM, Khayumbi J, Muchiri B, Ongalo J, Tonui J, Sasser LE, Fergus TJ, Ouma GS, Ouma SG, Beck AA, Mulligan MJ, Oladele A, Kaushal D, Cain KP, Waller L, Blumberg HM, Altman JD, Ernst JD, Rengarajan J, Day CL; TBRU-ASTRa Study Group.

J Immunol. 2018 Apr 15;200(8):3008-3019. doi: 10.4049/jimmunol.1701737. Epub 2018 Mar 14.


Deletion of BCG Hip1 protease enhances dendritic cell and CD4 T cell responses.

Bizzell E, Sia JK, Quezada M, Enriquez A, Georgieva M, Rengarajan J.

J Leukoc Biol. 2018 Apr;103(4):739-748. doi: 10.1002/JLB.4A0917-363RR. Epub 2017 Dec 28.


In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis.

Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, Rengarajan J, Khader SA, Kaushal D, Mehra S.

Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E62-E71. doi: 10.1073/pnas.1711373114. Epub 2017 Dec 18.


Mycobacterium tuberculosis GroEL2 Modulates Dendritic Cell Responses.

Georgieva M, Sia JK, Bizzell E, Madan-Lala R, Rengarajan J.

Infect Immun. 2018 Jan 22;86(2). pii: e00387-17. doi: 10.1128/IAI.00387-17. Print 2018 Feb.


Neutrophil extracellular trap (NET) levels in human plasma are associated with active TB.

Schechter MC, Buac K, Adekambi T, Cagle S, Celli J, Ray SM, Mehta CC, Rada B, Rengarajan J.

PLoS One. 2017 Aug 4;12(8):e0182587. doi: 10.1371/journal.pone.0182587. eCollection 2017.


Engaging the CD40-CD40L pathway augments T-helper cell responses and improves control of Mycobacterium tuberculosis infection.

Sia JK, Bizzell E, Madan-Lala R, Rengarajan J.

PLoS Pathog. 2017 Aug 2;13(8):e1006530. doi: 10.1371/journal.ppat.1006530. eCollection 2017 Aug.


Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c).

Naffin-Olivos JL, Daab A, White A, Goldfarb NE, Milne AC, Liu D, Baikovitz J, Dunn BM, Rengarajan J, Petsko GA, Ringe D.

Biochemistry. 2017 May 2;56(17):2304-2314. doi: 10.1021/acs.biochem.6b01066. Epub 2017 Apr 7.


Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis.

Kaushal D, Foreman TW, Gautam US, Alvarez X, Adekambi T, Rangel-Moreno J, Golden NA, Johnson AM, Phillips BL, Ahsan MH, Russell-Lodrigue KE, Doyle LA, Roy CJ, Didier PJ, Blanchard JL, Rengarajan J, Lackner AA, Khader SA, Mehra S.

Nat Commun. 2015 Oct 13;6:8533. doi: 10.1038/ncomms9533.


Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response.

Adekambi T, Ibegbu CC, Cagle S, Kalokhe AS, Wang YF, Hu Y, Day CL, Ray SM, Rengarajan J.

J Clin Invest. 2015 Sep;125(9):3723. doi: 10.1172/JCI83279. Epub 2015 Sep 1. No abstract available.


Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells.

Sia JK, Georgieva M, Rengarajan J.

J Immunol Res. 2015;2015:747543. doi: 10.1155/2015/747543. Epub 2015 Jul 14. Review.


Biomarkers on patient T cells diagnose active tuberculosis and monitor treatment response.

Adekambi T, Ibegbu CC, Cagle S, Kalokhe AS, Wang YF, Hu Y, Day CL, Ray SM, Rengarajan J.

J Clin Invest. 2015 May;125(5):1827-38. doi: 10.1172/JCI77990. Epub 2015 Mar 30. Erratum in: J Clin Invest. 2015 Sep;125(9):3723.


DosS Is required for the complete virulence of mycobacterium tuberculosis in mice with classical granulomatous lesions.

Gautam US, McGillivray A, Mehra S, Didier PJ, Midkiff CC, Kissee RS, Golden NA, Alvarez X, Niu T, Rengarajan J, Sherman DR, Kaushal D.

Am J Respir Cell Mol Biol. 2015 Jun;52(6):708-16. doi: 10.1165/rcmb.2014-0230OC.


Impaired degranulation and proliferative capacity of Mycobacterium tuberculosis-specific CD8+ T cells in HIV-infected individuals with latent tuberculosis.

Kalokhe AS, Adekambi T, Ibegbu CC, Ray SM, Day CL, Rengarajan J.

J Infect Dis. 2015 Feb 15;211(4):635-40. doi: 10.1093/infdis/jiu505. Epub 2014 Sep 9.


Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2.

Naffin-Olivos JL, Georgieva M, Goldfarb N, Madan-Lala R, Dong L, Bizzell E, Valinetz E, Brandt GS, Yu S, Shabashvili DE, Ringe D, Dunn BM, Petsko GA, Rengarajan J.

PLoS Pathog. 2014 May 15;10(5):e1004132. doi: 10.1371/journal.ppat.1004132. eCollection 2014 May.


Mycobacterium tuberculosis impairs dendritic cell functions through the serine hydrolase Hip1.

Madan-Lala R, Sia JK, King R, Adekambi T, Monin L, Khader SA, Pulendran B, Rengarajan J.

J Immunol. 2014 May 1;192(9):4263-72. doi: 10.4049/jimmunol.1303185. Epub 2014 Mar 21.


The intracellular environment of human macrophages that produce nitric oxide promotes growth of mycobacteria.

Jung JY, Madan-Lala R, Georgieva M, Rengarajan J, Sohaskey CD, Bange FC, Robinson CM.

Infect Immun. 2013 Sep;81(9):3198-209. doi: 10.1128/IAI.00611-13. Epub 2013 Jun 17.


Meeting report: The International Conference on Human Immunity to Tuberculosis.

Ernst JD, Hanekom W, Hawn T, Kampmann B, Rengarajan J.

Tuberculosis (Edinb). 2012 Sep;92(5):440-4. doi: 10.1016/ Epub 2012 Jun 2.


Distinct effector memory CD4+ T cell signatures in latent Mycobacterium tuberculosis infection, BCG vaccination and clinically resolved tuberculosis.

Adekambi T, Ibegbu CC, Kalokhe AS, Yu T, Ray SM, Rengarajan J.

PLoS One. 2012;7(4):e36046. doi: 10.1371/journal.pone.0036046. Epub 2012 Apr 24.


Mycobacterium tuberculosis Hip1 dampens macrophage proinflammatory responses by limiting toll-like receptor 2 activation.

Madan-Lala R, Peixoto KV, Re F, Rengarajan J.

Infect Immun. 2011 Dec;79(12):4828-38. doi: 10.1128/IAI.05574-11. Epub 2011 Sep 26.

Supplemental Content

Loading ...
Support Center