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Bioessays. 2012 Oct;34(10):867-70. doi: 10.1002/bies.201200083. Epub 2012 Aug 7.

Recombination between RNA viruses and plasmids might have played a central role in the origin and evolution of small DNA viruses.

Author information

1
Department of Microbiology, Institut Pasteur, Molecular Biology of the Gene in Extremophiles Unit, Paris, France. krupovic@pasteur.fr

Abstract

The finding that viruses with RNA and DNA genomes can recombine to produce chimeric entities provides valuable insights into the origin and evolution of viruses. It also substantiates the hypothesis that certain groups of DNA viruses could have emerged from plasmids via acquisition of capsid protein-coding genes from RNA viruses.

PMID:
22886750
DOI:
10.1002/bies.201200083
[Indexed for MEDLINE]

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