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First-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells.
Hojjat-Farsangi M, Daneshmanesh AH, Khan AS, Shetye J, Mozaffari F, Kharaziha P, Rathje LS, Kokhaei P, Hansson L, Vågberg J, Byström S, Olsson E, Löfberg C, Norström C, Schultz J, Norin M, Olin T, Österborg A, Mellstedt H, Moshfegh A. Hojjat-Farsangi M, et al. Among authors: rathje ls. Leukemia. 2018 Oct;32(10):2291-2295. doi: 10.1038/s41375-018-0113-1. Epub 2018 Mar 27. Leukemia. 2018. PMID: 29725030 Free PMC article. No abstract available.
PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription.
Zhao H, Sifakis EG, Sumida N, Millán-Ariño L, Scholz BA, Svensson JP, Chen X, Ronnegren AL, Mallet de Lima CD, Varnoosfaderani FS, Shi C, Loseva O, Yammine S, Israelsson M, Rathje LS, Németi B, Fredlund E, Helleday T, Imreh MP, Göndör A. Zhao H, et al. Among authors: rathje ls. Mol Cell. 2015 Sep 17;59(6):984-97. doi: 10.1016/j.molcel.2015.07.019. Epub 2015 Aug 27. Mol Cell. 2015. PMID: 26321255 Free article.