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Items: 1 to 20 of 124


Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.

Roy NS, Jian X, Soubias O, Zhai P, Hall JR, Dagher JN, Coussens NP, Jenkins LM, Luo R, Akpan IO, Hall MD, Byrd RA, Yohe ME, Randazzo PA.

J Biol Chem. 2019 Oct 6. pii: jbc.RA119.009269. doi: 10.1074/jbc.RA119.009269. [Epub ahead of print]


Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers.

Colombo E, Biocotino M, Frapporti G, Randazzo P, Christodoulou MS, Piccoli G, Polito L, Seneci P, Passarella D.

Pharmaceutics. 2019 Aug 20;11(8). pii: E422. doi: 10.3390/pharmaceutics11080422.


Multiplex genome editing of microorganisms using CRISPR-Cas.

Adiego-Pérez B, Randazzo P, Daran JM, Verwaal R, Roubos JA, Daran-Lapujade P, van der Oost J.

FEMS Microbiol Lett. 2019 Apr 1;366(8). pii: fnz086. doi: 10.1093/femsle/fnz086.


ARF GTPases and their GEFs and GAPs: concepts and challenges.

Sztul E, Chen PW, Casanova JE, Cherfils J, Dacks JB, Lambright DG, Lee FS, Randazzo PA, Santy LC, Schürmann A, Wilhelmi I, Yohe ME, Kahn RA.

Mol Biol Cell. 2019 May 15;30(11):1249-1271. doi: 10.1091/mbc.E18-12-0820.


Identification of Isoform 2 Acid-Sensing Ion Channel Inhibitors as Tool Compounds for Target Validation Studies in CNS.

Bencheva LI, De Matteo M, Ferrante L, Ferrara M, Prandi A, Randazzo P, Ronzoni S, Sinisi R, Seneci P, Summa V, Gallo M, Veneziano M, Cellucci A, Mazzocchi N, Menegon A, Di Fabio R.

ACS Med Chem Lett. 2019 Feb 7;10(4):627-632. doi: 10.1021/acsmedchemlett.8b00591. eCollection 2019 Apr 11.


Functional Expression and Characterization of Human Myristoylated-Arf1 in Nanodisc Membrane Mimetics.

Li Y, Soubias O, Li J, Sun S, Randazzo PA, Byrd RA.

Biochemistry. 2019 Mar 12;58(10):1423-1431. doi: 10.1021/acs.biochem.8b01323. Epub 2019 Feb 20.


ARAP2 inhibits Akt independently of its effects on focal adhesions.

Luo R, Chen PW, Kuo JC, Jenkins L, Jian X, Waterman CM, Randazzo PA.

Biol Cell. 2018 Dec;110(12):257-270. doi: 10.1111/boc.201800044. Epub 2018 Sep 10.


The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding.

Madigan JP, Hou F, Ye L, Hu J, Dong A, Tempel W, Yohe ME, Randazzo PA, Jenkins LMM, Gottesman MM, Tong Y.

J Biol Chem. 2018 Oct 19;293(42):16142-16159. doi: 10.1074/jbc.RA118.003525. Epub 2018 Aug 24.


Revisiting the in vivo GlnR-binding sites at the genome scale in Bacillus subtilis.

Randazzo P, Aucouturier A, Delumeau O, Auger S.

BMC Res Notes. 2017 Aug 23;10(1):422. doi: 10.1186/s13104-017-2703-9.


Arf GAPs and molecular motors.

Luo R, Reed CE, Sload JA, Wordeman L, Randazzo PA, Chen PW.

Small GTPases. 2019 May;10(3):196-209. doi: 10.1080/21541248.2017.1308850. Epub 2017 Apr 21.


Arf GAPs: A family of proteins with disparate functions that converge on a common structure, the integrin adhesion complex.

Vitali T, Girald-Berlingeri S, Randazzo PA, Chen PW.

Small GTPases. 2019 Jul;10(4):280-288. doi: 10.1080/21541248.2017.1299271. Epub 2017 Mar 31.


Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1).

Luo R, Chen PW, Wagenbach M, Jian X, Jenkins L, Wordeman L, Randazzo PA.

J Biol Chem. 2016 Dec 2;291(49):25761. No abstract available.


The MarR-like protein PchR (YvmB) regulates expression of genes involved in pulcherriminic acid biosynthesis and in the initiation of sporulation in Bacillus subtilis.

Randazzo P, Aubert-Frambourg A, Guillot A, Auger S.

BMC Microbiol. 2016 Aug 20;16(1):190. doi: 10.1186/s12866-016-0807-3.


Direct Functional Interaction of the Kinesin-13 Family Member Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1).

Luo R, Chen PW, Wagenbach M, Jian X, Jenkins L, Wordeman L, Randazzo PA.

J Biol Chem. 2016 Oct 7;291(41):21350-21362. doi: 10.1074/jbc.M116.732479. Epub 2016 Aug 16. Erratum in: J Biol Chem. 2016 Dec 2;291(49):25761.


Allosteric properties of PH domains in Arf regulatory proteins.

Roy NS, Yohe ME, Randazzo PA, Gruschus JM.

Cell Logist. 2016 Apr 26;6(2):e1181700. eCollection 2016 Apr-Jun. Review.


The Arf GTPase-activating Protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network.

Chen PW, Jian X, Heissler SM, Le K, Luo R, Jenkins LM, Nagy A, Moss J, Sellers JR, Randazzo PA.

J Biol Chem. 2016 Apr 1;291(14):7517-26. doi: 10.1074/jbc.M115.701292. Epub 2016 Feb 17.


Polygenic analysis and targeted improvement of the complex trait of high acetic acid tolerance in the yeast Saccharomyces cerevisiae.

Meijnen JP, Randazzo P, Foulquié-Moreno MR, van den Brink J, Vandecruys P, Stojiljkovic M, Dumortier F, Zalar P, Boekhout T, Gunde-Cimerman N, Kokošar J, Štajdohar M, Curk T, Petrovič U, Thevelein JM.

Biotechnol Biofuels. 2016 Jan 6;9:5. doi: 10.1186/s13068-015-0421-x. eCollection 2016.


Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.

Li S, Liang YH, Mariano J, Metzger MB, Stringer DK, Hristova VA, Li J, Randazzo PA, Tsai YC, Ji X, Weissman AM.

J Biol Chem. 2015 Dec 18;290(51):30225-39. doi: 10.1074/jbc.M115.685867. Epub 2015 Oct 16.


Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.

Jian X, Tang WK, Zhai P, Roy NS, Luo R, Gruschus JM, Yohe ME, Chen PW, Li Y, Byrd RA, Xia D, Randazzo PA.

Structure. 2015 Nov 3;23(11):1977-88. doi: 10.1016/j.str.2015.08.008. Epub 2015 Sep 10.


Simple in vitro assay of Arf GAPs and preparation of Arf proteins as substrates.

Chen PW, Jian X, Luo R, Randazzo PA.

Methods Cell Biol. 2015;130:69-80. doi: 10.1016/bs.mcb.2015.03.021. Epub 2015 Jun 11.


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