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Discovery of first-in-class nanomolar inhibitors of heptosyltransferase I reveals a new aminoglycoside target and potential alternative mechanism of action.
Milicaj J, Hassan BA, Cote JM, Ramirez-Mondragon CA, Jaunbocus N, Rafalowski A, Patel KR, Castro CD, Muthyala R, Sham YY, Taylor EA. Milicaj J, et al. Among authors: ramirez mondragon ca. Sci Rep. 2022 May 4;12(1):7302. doi: 10.1038/s41598-022-10776-x. Sci Rep. 2022. PMID: 35508636 Free PMC article.