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Health-Related Quality of Life in Patients with Spinocerebellar Ataxia: a Validation Study of the EQ-5D-3L.
Buchholz M, Weber N, Rädke A, Faber J, Schmitz-Hübsch T, Jacobi H, Xie F, Klockgether T, Michalowsky B; EUROSCA study group; ESMI study group. Buchholz M, et al. Cerebellum. 2023 Sep 15. doi: 10.1007/s12311-023-01597-3. Online ahead of print. Cerebellum. 2023. PMID: 37713052
The non-item response was low (EQ-5D-3L index: 0.8%; EQ-VAS: 3.4%). Ceiling effects occurred in 9.9% (EQ-5D-3L) and 3.0% (EQ-VAS) with a mean EQ-5D-3L index of 0.65 0.21. ...Intra-class correlation coefficients (EQ-5D-3L(ICC): 0.95/EQ-VAS(ICC): 0.88) a …
The non-item response was low (EQ-5D-3L index: 0.8%; EQ-VAS: 3.4%). Ceiling effects occurred in 9.9% (EQ-5D-3L) and 3.0% (EQ-V …
Fluctuations of health states in dementia diseases and their impact on the assessment of health today using the EQ-5D-5L: Protocol of a mixed-methods study.
Weber N, Xie F, Kohlmann T, Mohr W, Platen M, Rädke A, Kilimann I, Engel L, Michalowsky B. Weber N, et al. Front Public Health. 2023 Mar 16;11:1031978. doi: 10.3389/fpubh.2023.1031978. eCollection 2023. Front Public Health. 2023. PMID: 37006562 Free PMC article. Clinical Trial.
INTRODUCTION: The EQ-5D is a widely used health-related quality of life (HRQoL) instrument. ...Thus, this study aims to assess the frequency of health fluctuations, affected HRQoL dimensions and the impact of the health fluctuations on the assessment of health today using …
INTRODUCTION: The EQ-5D is a widely used health-related quality of life (HRQoL) instrument. ...Thus, this study aims to assess the fr …
Comparing the psychometric properties of EQ-5D-3L and EQ-5D-5L proxy ratings by informal caregivers and a health professional for people with dementia.
Michalowsky B, Hoffmann W, Mohr W, Rädke A, Xie F. Michalowsky B, et al. Health Qual Life Outcomes. 2022 Oct 5;20(1):140. doi: 10.1186/s12955-022-02049-y. Health Qual Life Outcomes. 2022. PMID: 36199138 Free PMC article.
Methodological drawbacks of the three-level version (EQ-5D-3L) prompted the development of the five-level version (EQ-5D-5L) by expanding the range in the domains. ...Therefore, the objective of this study was to compare the psychometric properties of the EQ-5D
Methodological drawbacks of the three-level version (EQ-5D-3L) prompted the development of the five-level version (EQ-5D-5L) b …
Factors Influencing Health-Related Quality of Life of Patients with Spinocerebellar Ataxia.
Weber N, Buchholz M, Rädke A, Faber J, Schmitz-Hübsch T, Jacobi H, Klockgether T, Hoffmann W, Michalowsky B; EUROSCA study group; ESMI study group. Weber N, et al. Cerebellum. 2024 Jan 27. doi: 10.1007/s12311-024-01657-2. Online ahead of print. Cerebellum. 2024. PMID: 38279001
Both large cohort studies share standardized assessments of clinical measures, SARA, INAS, PHQ-9, and HRQoL (EQ-5D-3L). The association between HRQoL and clinical measures was assessed by Spearman Correlation (r(s)). ...
Both large cohort studies share standardized assessments of clinical measures, SARA, INAS, PHQ-9, and HRQoL (EQ-5D-3L). The associati …
Cardiac muscarinic receptors decrease with age. In vitro and in vivo studies.
Brodde OE, Konschak U, Becker K, Rüter F, Poller U, Jakubetz J, Radke J, Zerkowski HR. Brodde OE, et al. J Clin Invest. 1998 Jan 15;101(2):471-8. doi: 10.1172/JCI1113. J Clin Invest. 1998. PMID: 9435320 Free PMC article.
The M1 muscarinic receptor antagonist pirenzepine in low doses decreases resting heart rate; this effect declines with age (Poller, U., G. Nedelka, J. Radke, K. Ponicke, and O.-E. Brodde. 1997. J. Am. Coll. Cardiol. 29:187-193). ...
The M1 muscarinic receptor antagonist pirenzepine in low doses decreases resting heart rate; this effect declines with age (Poller, U., G. N …
Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial.
Thiele H, Zeymer U, Neumann FJ, Ferenc M, Olbrich HG, Hausleiter J, de Waha A, Richardt G, Hennersdorf M, Empen K, Fuernau G, Desch S, Eitel I, Hambrecht R, Lauer B, Böhm M, Ebelt H, Schneider S, Werdan K, Schuler G; Intraaortic Balloon Pump in cardiogenic shock II (IABP-SHOCK II) trial investigators. Thiele H, et al. Lancet. 2013 Nov 16;382(9905):1638-45. doi: 10.1016/S0140-6736(13)61783-3. Epub 2013 Sep 3. Lancet. 2013. PMID: 24011548 Clinical Trial.
The primary efficacy endpoint was 30 day all-cause mortality, but 6 and 12 month follow-up was done in addition to quality-of-life assessment for all survivors with the Euroqol-5D questionnaire. A masked central committee adjudicated clinical outcomes. ...
The primary efficacy endpoint was 30 day all-cause mortality, but 6 and 12 month follow-up was done in addition to quality-of-life assessmen …