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Items: 1 to 20 of 27


Cutting Edge: Elevated Glycolytic Metabolism Limits the Formation of Memory CD8+ T Cells in Early Life.

Tabilas C, Wang J, Liu X, Locasale JW, Smith NL, Rudd BD.

J Immunol. 2019 Nov 15;203(10):2571-2576. doi: 10.4049/jimmunol.1900426. Epub 2019 Oct 9.


Differential Sensitivity to IL-12 Drives Sex-Specific Differences in the CD8+ T Cell Response to Infection.

Yee Mon KJ, Goldsmith E, Watson NB, Wang J, Smith NL, Rudd BD.

Immunohorizons. 2019 Apr;3(4):121-132. doi: 10.4049/immunohorizons.1800066.


Fate mapping reveals the age structure of the peripheral T cell compartment.

Reynaldi A, Smith NL, Schlub TE, Tabilas C, Venturi V, Rudd BD, Davenport MP.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):3974-3981. doi: 10.1073/pnas.1811634116. Epub 2019 Feb 14.


Developmental Origin Governs CD8+ T Cell Fate Decisions during Infection.

Smith NL, Patel RK, Reynaldi A, Grenier JK, Wang J, Watson NB, Nzingha K, Yee Mon KJ, Peng SA, Grimson A, Davenport MP, Rudd BD.

Cell. 2018 Jun 28;174(1):117-130.e14. doi: 10.1016/j.cell.2018.05.029. Epub 2018 Jun 14.


Fetal and adult progenitors give rise to unique populations of CD8+ T cells.

Wang J, Wissink EM, Watson NB, Smith NL, Grimson A, Rudd BD.

Blood. 2016 Dec 29;128(26):3073-3082. doi: 10.1182/blood-2016-06-725366. Epub 2016 Nov 15.


Modeling the dynamics of neonatal CD8+ T-cell responses.

Reynaldi A, Smith NL, Schlub TE, Venturi V, Rudd BD, Davenport MP.

Immunol Cell Biol. 2016 Oct;94(9):838-848. doi: 10.1038/icb.2016.47. Epub 2016 May 4.


The Neonatal CD8+ T Cell Repertoire Rapidly Diversifies during Persistent Viral Infection.

Venturi V, Nzingha K, Amos TG, Charles WC, Dekhtiarenko I, Cicin-Sain L, Davenport MP, Rudd BD.

J Immunol. 2016 Feb 15;196(4):1604-16. doi: 10.4049/jimmunol.1501867. Epub 2016 Jan 13.


miR-150 Regulates Differentiation and Cytolytic Effector Function in CD8+ T cells.

Smith NL, Wissink EM, Grimson A, Rudd BD.

Sci Rep. 2015 Nov 9;5:16399. doi: 10.1038/srep16399.


MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells.

Wissink EM, Smith NL, Spektor R, Rudd BD, Grimson A.

Genetics. 2015 Nov;201(3):1017-30. doi: 10.1534/genetics.115.179176. Epub 2015 Sep 28.


Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells.

Cohen SB, Smith NL, McDougal C, Pepper M, Shah S, Yap GS, Acha-Orbea H, Jiang A, Clausen BE, Rudd BD, Denkers EY.

J Immunol. 2015 Jan 1;194(1):210-22.


Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life.

Smith NL, Wissink E, Wang J, Pinello JF, Davenport MP, Grimson A, Rudd BD.

J Immunol. 2014 Jul 1;193(1):177-84. doi: 10.4049/jimmunol.1400553. Epub 2014 May 21.


Acute neonatal infections 'lock-in' a suboptimal CD8+ T cell repertoire with impaired recall responses.

Rudd BD, Venturi V, Smith NL, Nzingha K, Goldberg EL, Li G, Nikolich-Zugich J, Davenport MP.

PLoS Pathog. 2013 Sep;9(9):e1003572. doi: 10.1371/journal.ppat.1003572. Epub 2013 Sep 12.


Specificity, promiscuity, and precursor frequency in immunoreceptors.

Venturi V, Rudd BD, Davenport MP.

Curr Opin Immunol. 2013 Oct;25(5):639-45. doi: 10.1016/j.coi.2013.07.001. Epub 2013 Jul 20. Review.


Age-associated alterations in CD8α+ dendritic cells impair CD8 T-cell expansion in response to an intracellular bacterium.

Li G, Smithey MJ, Rudd BD, Nikolich-Žugich J.

Aging Cell. 2012 Dec;11(6):968-77. doi: 10.1111/j.1474-9726.2012.00867.x. Epub 2012 Aug 30.


Nonrandom attrition of the naive CD8+ T-cell pool with aging governed by T-cell receptor:pMHC interactions.

Rudd BD, Venturi V, Li G, Samadder P, Ertelt JM, Way SS, Davenport MP, Nikolich-Žugich J.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13694-9. doi: 10.1073/pnas.1107594108. Epub 2011 Aug 3.


Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice.

Smithey MJ, Renkema KR, Rudd BD, Nikolich-Žugich J.

Eur J Immunol. 2011 May;41(5):1352-64. doi: 10.1002/eji.201041141. Epub 2011 Apr 14.


Evolution of the antigen-specific CD8+ TCR repertoire across the life span: evidence for clonal homogenization of the old TCR repertoire.

Rudd BD, Venturi V, Davenport MP, Nikolich-Zugich J.

J Immunol. 2011 Feb 15;186(4):2056-2064. doi: 10.4049/jimmunol.1003013. Epub 2011 Jan 19.


Immune memory and aging: an infinite or finite resource?

Nikolich-Zugich J, Rudd BD.

Curr Opin Immunol. 2010 Aug;22(4):535-40. doi: 10.1016/j.coi.2010.06.011. Epub 2010 Jul 30. Review.


Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection.

Rudd BD, Venturi V, Smithey MJ, Way SS, Davenport MP, Nikolich-Zugich J.

J Immunol. 2010 Mar 15;184(6):2958-2965. doi: 10.4049/jimmunol.0903493. Epub 2010 Feb 17.


Cutting edge: TLR ligands increase TCR triggering by slowing peptide-MHC class I decay rates.

Rudd BD, Brien JD, Davenport MP, Nikolich-Zugich J.

J Immunol. 2008 Oct 15;181(8):5199-203.

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