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Pathol Biol (Paris). 2014 Aug;62(4):218-20. doi: 10.1016/j.patbio.2014.05.005. Epub 2014 Jul 1.

Quality controls on cord blood unit contiguous segments: recommendation of the SFGM-TC.

Author information

1
Unité de thérapie cellulaire, CHU de Montpellier, 80, avenue Fliche, 34295 Montpellier cedex 5, France.
2
UITC, EFS Île-de-France, 5, rue Gustave-Eiffel, 94017 Créteil cedex, France.
3
Direction médicale et scientifique, agence de la biomédecine, 1, avenue du Stade-de-France, 93212 Saint-Denis, France.
4
Laboratoire de thérapie cellulaire et génique, CHU de Liège, tour 2 niveau-4E, 4000 Liège, Belgium.
5
Département d'hématologie clinique, CHRU de Montpellier, 80, avenue Augustin-Fliche, 34295 Montpellier cedex 5, France.
6
Département de thérapie cellulaire, institut Paoli-Calmettes, 232, boulevard Sainte-Marguerite, BP 156, 13273 Marseille cedex 09, France.
7
EFS Nord de France, 21, rue Camille-Guérin, BP 2018, 59012 Lille cedex, France.
8
Registre France greffe de moelle, agence de la biomédecine, 1, avenue du Stade-de-France, 93212 Saint-Denis, France.
9
Unité de thérapie cellulaire et de clinique transfusionnelle, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris cedex 10, France.
10
EFS BFC, activité ingénierie cellulaire et tissulaire, 1, boulevard A.-Fleming, 25020 Besançon cedex, France.
11
Service de thérapie cellulaire, EFS Bretagne, rue Pierre-Jean Gineste, BP 91614, 35016 Rennes cedex, France.
12
Maladies du sang, CHRU de Lille, rue Michel-Polonovski, 59037 Lille cedex, France. Electronic address: sfgm-tc-iya@live.fr.

Abstract

In the attempt to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapies (SFGM-TC) set up its fourth annual series of workshops which brought together practitioners from all of its member centers. These workshops took place in September 2013 in Lille. Literature and intra-laboratories studies suggest that attached segment is representative of cord blood unit (CBU). Nevertheless, some discrepancies have been observed when analyzing large data registries. To address these issues, we have listed recommendations to increase the standardization of segment processing and quality control (QC), information on units of measurement and specifications and action to be taken in case of out of specifications QC results on segment.

KEYWORDS:

Attached segment; BU release; Cord blood transplantation; Greffe de sang de cordon; Segment attaché; Specifications; Spécifications

PMID:
24996845
DOI:
10.1016/j.patbio.2014.05.005
[Indexed for MEDLINE]
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