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Items: 20


TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice.

Haribhai D, Luo X, Chen J, Jia S, Shi L, Schroeder JA, Weiler H, Aster RH, Hessner MJ, Hu J, Williams CB, Shi Q.

Blood Adv. 2016 Dec 13;1(2):139-151. doi: 10.1182/bloodadvances.2016001453.


The immunogenicity of platelet-derived FVIII in hemophilia A mice with or without preexisting anti-FVIII immunity.

Chen Y, Schroeder JA, Chen J, Luo X, Baumgartner CK, Montgomery RR, Hu J, Shi Q.

Blood. 2016 Mar 10;127(10):1346-54. doi: 10.1182/blood-2015-08-662916. Epub 2015 Dec 14.


A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII.

Fahs SA, Hille MT, Shi Q, Weiler H, Montgomery RR.

Blood. 2014 Jun 12;123(24):3706-13. doi: 10.1182/blood-2014-02-555151. Epub 2014 Apr 4.


Platelet Gene Therapy by Lentiviral Gene Delivery to Hematopoietic Stem Cells Restores Hemostasis and Induces Humoral Immune Tolerance in FIXnull Mice.

Chen Y, Schroeder JA, Kuether EL, Zhang G, Shi Q.

Mol Ther. 2014 Jan;22(1):169-177. doi: 10.1038/mt.2013.197. Epub 2016 Dec 6.


Platelet gene therapy corrects the hemophilic phenotype in immunocompromised hemophilia A mice transplanted with genetically manipulated human cord blood stem cells.

Shi Q, Kuether EL, Chen Y, Schroeder JA, Fahs SA, Montgomery RR.

Blood. 2014 Jan 16;123(3):395-403. doi: 10.1182/blood-2013-08-520478. Epub 2013 Nov 22.


Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A.

Du LM, Nurden P, Nurden AT, Nichols TC, Bellinger DA, Jensen ES, Haberichter SL, Merricks E, Raymer RA, Fang J, Koukouritaki SB, Jacobi PM, Hawkins TB, Cornetta K, Shi Q, Wilcox DA.

Nat Commun. 2013;4:2773. doi: 10.1038/ncomms3773.


Platelet gene therapy by lentiviral gene delivery to hematopoietic stem cells restores hemostasis and induces humoral immune tolerance in FIX(null) mice.

Chen Y, Schroeder JA, Kuether EL, Zhang G, Shi Q.

Mol Ther. 2014 Jan;22(1):169-77. doi: 10.1038/mt.2013.197. Epub 2013 Aug 23.


Platelet and endothelial expression of clotting factors for the treatment of hemophilia.

Montgomery RR, Shi Q.

Thromb Res. 2012 May;129 Suppl 2:S46-8. doi: 10.1016/j.thromres.2012.02.031. Epub 2012 Mar 14. Review.


Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy.

Kanaji S, Kuether EL, Fahs SA, Schroeder JA, Ware J, Montgomery RR, Shi Q.

Mol Ther. 2012 Mar;20(3):625-32. doi: 10.1038/mt.2011.231. Epub 2011 Nov 1.


Alternative strategies for gene therapy of hemophilia.

Montgomery RR, Shi Q.

Hematology Am Soc Hematol Educ Program. 2010;2010:197-202. doi: 10.1182/asheducation-2010.1.197.


Platelets as delivery systems for disease treatments.

Shi Q, Montgomery RR.

Adv Drug Deliv Rev. 2010 Sep 30;62(12):1196-203. doi: 10.1016/j.addr.2010.06.007. Epub 2010 Jul 7. Review.


Targeting FVIII expression to endothelial cells regenerates a releasable pool of FVIII and restores hemostasis in a mouse model of hemophilia A.

Shi Q, Fahs SA, Kuether EL, Cooley BC, Weiler H, Montgomery RR.

Blood. 2010 Oct 21;116(16):3049-57. doi: 10.1182/blood-2010-03-272419. Epub 2010 Jul 6.


Factor IX ectopically expressed in platelets can be stored in alpha-granules and corrects the phenotype of hemophilia B mice.

Zhang G, Shi Q, Fahs SA, Kuether EL, Walsh CE, Montgomery RR.

Blood. 2010 Aug 26;116(8):1235-43. doi: 10.1182/blood-2009-11-255612. Epub 2010 May 5.


Syngeneic transplantation of hematopoietic stem cells that are genetically modified to express factor VIII in platelets restores hemostasis to hemophilia A mice with preexisting FVIII immunity.

Shi Q, Fahs SA, Wilcox DA, Kuether EL, Morateck PA, Mareno N, Weiler H, Montgomery RR.

Blood. 2008 Oct 1;112(7):2713-21. doi: 10.1182/blood-2008-02-138214. Epub 2008 May 21.


Pyrolysis mechanism of carbon matrix precursor cyclohexane--the formation of condensed-ring aromatics and the growing process of molecules.

Wang H, Yang H, Chuang W, Ran X, Shi Q, Wen Z.

J Mol Graph Model. 2007 Mar;25(6):824-30. Epub 2006 Sep 25.


Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies.

Shi Q, Wilcox DA, Fahs SA, Weiler H, Wells CW, Cooley BC, Desai D, Morateck PA, Gorski J, Montgomery RR.

J Clin Invest. 2006 Jul;116(7):1974-82.


Thermal decomposition kinetics of the Pb0.25Ba0.75(TNR).H2O complex.

Hu R, Chen S, Gao S, Zhao F, Luo Y, Gao H, Shi Q, Zhao H, Yao P, Li J.

J Hazard Mater. 2005 Jan 31;117(2-3):103-10.


On the interconversion pathway of HBO<-->BOH.

Peng Q, Wang Y, Suo B, Shi Q, Wen Z.

J Chem Phys. 2004 Jul 8;121(2):778-82.


Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment.

Yarovoi HV, Kufrin D, Eslin DE, Thornton MA, Haberichter SL, Shi Q, Zhu H, Camire R, Fakharzadeh SS, Kowalska MA, Wilcox DA, Sachais BS, Montgomery RR, Poncz M.

Blood. 2003 Dec 1;102(12):4006-13. Epub 2003 Jul 24.


Estimation of the critical rate of temperature rise for thermal explosion of first-order autocatalytic decomposition reaction systems using non-isothermal DSC.

Hai Z, Zhiming X, Pengjiang G, Rongzu H, Shengli G, Binke N, Yan F, Qizhen S, Rong L.

J Hazard Mater. 2002 Oct 14;94(3):205-10.


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