Pye CR[Author] - Search Results

Year	Number of Results
2015	3
2016	3
2017	3
2018	2
2020	2
2021	1
2022	1
2023	2
2024	1

1

NP Analyst: An Open Online Platform for Compound Activity Mapping.

Lee S, van Santen JA, Farzaneh N, Liu DY, Pye CR, Baumeister TUH, Wong WR, Linington RG. Lee S, et al. Among authors: pye cr. ACS Cent Sci. 2022 Feb 23;8(2):223-234. doi: 10.1021/acscentsci.1c01108. Epub 2022 Jan 24. ACS Cent Sci. 2022. PMID: 35233454 Free PMC article.

2

DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2-p53 Inhibitor.

Silvestri AP, Zhang Q, Ping Y, Muir EW, Zhao J, Chakka SK, Wang G, Bray WM, Chen W, Fribourgh JL, Tripathi S, He Y, Rubin SM, Satz AL, Pye CR, Kuai L, Su W, Schwochert JA. Silvestri AP, et al. Among authors: pye cr. ACS Med Chem Lett. 2023 May 5;14(6):820-826. doi: 10.1021/acsmedchemlett.3c00117. eCollection 2023 Jun 8. ACS Med Chem Lett. 2023. PMID: 37312849

3

Drug-Like Properties in Macrocycles above MW 1000: Backbone Rigidity versus Side-Chain Lipophilicity.

Furukawa A, Schwochert J, Pye CR, Asano D, Edmondson QD, Turmon AC, Klein VG, Ono S, Okada O, Lokey RS. Furukawa A, et al. Among authors: pye cr. Angew Chem Int Ed Engl. 2020 Nov 23;59(48):21571-21577. doi: 10.1002/anie.202004550. Epub 2020 Sep 17. Angew Chem Int Ed Engl. 2020. PMID: 32789999 Free PMC article.

4

A Strategy for Direct Chemical Activation of the Retinoblastoma Protein.

Pye CR, Bray WM, Brown ER, Burke JR, Lokey RS, Rubin SM. Pye CR, et al. ACS Chem Biol. 2016 May 20;11(5):1192-7. doi: 10.1021/acschembio.6b00011. Epub 2016 Feb 11. ACS Chem Biol. 2016. PMID: 26845289 Free PMC article.

5

Geometrically Diverse Lariat Peptide Scaffolds Reveal an Untapped Chemical Space of High Membrane Permeability.

Kelly CN, Townsend CE, Jain AN, Naylor MR, Pye CR, Schwochert J, Lokey RS. Kelly CN, et al. Among authors: pye cr. J Am Chem Soc. 2021 Jan 20;143(2):705-714. doi: 10.1021/jacs.0c06115. Epub 2020 Dec 31. J Am Chem Soc. 2021. PMID: 33381960 Free PMC article.

6

CycLS: Accurate, whole-library sequencing of cyclic peptides using tandem mass spectrometry.

Townsend C, Furukawa A, Schwochert J, Pye CR, Edmondson Q, Lokey RS. Townsend C, et al. Among authors: pye cr. Bioorg Med Chem. 2018 Mar 15;26(6):1232-1238. doi: 10.1016/j.bmc.2018.01.027. Epub 2018 Feb 3. Bioorg Med Chem. 2018. PMID: 29459147

7

Determining predictive metabolomic biomarkers of meniscal injury in dogs with cranial cruciate ligament rupture.

Pye CR, Green DC, Anderson JR, Phelan MM, Fitzgerald MM, Comerford EJ, Peffers MJ. Pye CR, et al. J Small Anim Pract. 2024 Feb;65(2):90-103. doi: 10.1111/jsap.13688. Epub 2023 Nov 27. J Small Anim Pract. 2024. PMID: 38013167

8

Retrospective analysis of natural products provides insights for future discovery trends.

Pye CR, Bertin MJ, Lokey RS, Gerwick WH, Linington RG. Pye CR, et al. Proc Natl Acad Sci U S A. 2017 May 30;114(22):5601-5606. doi: 10.1073/pnas.1614680114. Epub 2017 May 1. Proc Natl Acad Sci U S A. 2017. PMID: 28461474 Free PMC article.

9

Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility.

Naylor MR, Ly AM, Handford MJ, Ramos DP, Pye CR, Furukawa A, Klein VG, Noland RP, Edmondson Q, Turmon AC, Hewitt WM, Schwochert J, Townsend CE, Kelly CN, Blanco MJ, Lokey RS. Naylor MR, et al. Among authors: pye cr. J Med Chem. 2018 Dec 27;61(24):11169-11182. doi: 10.1021/acs.jmedchem.8b01259. Epub 2018 Dec 11. J Med Chem. 2018. PMID: 30395703

10

Cell-permeable cyclic peptides from synthetic libraries inspired by natural products.

Hewitt WM, Leung SS, Pye CR, Ponkey AR, Bednarek M, Jacobson MP, Lokey RS. Hewitt WM, et al. Among authors: pye cr. J Am Chem Soc. 2015 Jan 21;137(2):715-21. doi: 10.1021/ja508766b. Epub 2015 Jan 8. J Am Chem Soc. 2015. PMID: 25517352

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