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Items: 1 to 20 of 61

1.

Editorial: Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease.

Pulinilkunnil T, Kienesberger P, Nagendran J.

Front Cardiovasc Med. 2019 Jul 12;6:97. doi: 10.3389/fcvm.2019.00097. eCollection 2019. No abstract available.

2.

Role of branched-chain amino acid-catabolizing enzymes in intertissue signaling, metabolic remodeling, and energy homeostasis.

Biswas D, Duffley L, Pulinilkunnil T.

FASEB J. 2019 Aug;33(8):8711-8731. doi: 10.1096/fj.201802842RR. Epub 2019 May 14.

PMID:
31084571
3.

Heparanase protects the heart against chemical or ischemia/reperfusion injury.

Wang F, Pulinilkunnil T, Flibotte S, Nislow C, Vlodavsky I, Hussein B, Rodrigues B.

J Mol Cell Cardiol. 2019 Jun;131:29-40. doi: 10.1016/j.yjmcc.2019.04.008. Epub 2019 Apr 17.

PMID:
31004678
4.

Impact of Obesity on Postoperative Outcomes following cardiac Surgery (The OPOS study): rationale and design of an investigator-initiated prospective study.

Aguiar C, MacLeod J, Yip A, Melville S, Légaré JF, Pulinilkunnil T, Kienesberger P, Brunt K, Hassan A.

BMJ Open. 2019 Mar 3;9(3):e023418. doi: 10.1136/bmjopen-2018-023418.

5.

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism.

D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC.

J Lipid Res. 2018 Oct;59(10):1805-1817. doi: 10.1194/jlr.M082008. Epub 2018 Aug 2.

6.

Lysophosphatidic acid receptor mRNA levels in heart and white adipose tissue are associated with obesity in mice and humans.

Brown A, Hossain I, Perez LJ, Nzirorera C, Tozer K, D'Souza K, Trivedi PC, Aguiar C, Yip AM, Shea J, Brunt KR, Legare JF, Hassan A, Pulinilkunnil T, Kienesberger PC.

PLoS One. 2017 Dec 13;12(12):e0189402. doi: 10.1371/journal.pone.0189402. eCollection 2017.

7.

The MiTF/TFE Family of Transcription Factors: Master Regulators of Organelle Signaling, Metabolism, and Stress Adaptation.

Slade L, Pulinilkunnil T.

Mol Cancer Res. 2017 Dec;15(12):1637-1643. doi: 10.1158/1541-7786.MCR-17-0320. Epub 2017 Aug 29. Review.

8.

Cardiac complications of congenital disorders of glycosylation (CDG): a systematic review of the literature.

Marques-da-Silva D, Francisco R, Webster D, Dos Reis Ferreira V, Jaeken J, Pulinilkunnil T.

J Inherit Metab Dis. 2017 Sep;40(5):657-672. doi: 10.1007/s10545-017-0066-y. Epub 2017 Jul 19. Review.

PMID:
28726068
9.

Validation of optimal reference genes for quantitative real time PCR in muscle and adipose tissue for obesity and diabetes research.

Perez LJ, Rios L, Trivedi P, D'Souza K, Cowie A, Nzirorera C, Webster D, Brunt K, Legare JF, Hassan A, Kienesberger PC, Pulinilkunnil T.

Sci Rep. 2017 Jun 15;7(1):3612. doi: 10.1038/s41598-017-03730-9.

10.

Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio).

Slade L, Cowie A, Martyniuk CJ, Kienesberger PC, Pulinilkunnil T.

J Pharmacol Exp Ther. 2017 Jun;361(3):375-385. doi: 10.1124/jpet.116.239806. Epub 2017 Apr 6.

PMID:
28385952
11.

Changes in Circulating Monocyte Subsets (CD16 Expression) and Neutrophil-to-Lymphocyte Ratio Observed in Patients Undergoing Cardiac Surgery.

Gawdat K, Legere S, Wong C, Myers T, Marshall JS, Hassan A, Brunt KR, Kienesberger PC, Pulinilkunnil T, Legare JF.

Front Cardiovasc Med. 2017 Mar 15;4:12. doi: 10.3389/fcvm.2017.00012. eCollection 2017.

12.

Autotaxin Is Regulated by Glucose and Insulin in Adipocytes.

D'Souza K, Kane DA, Touaibia M, Kershaw EE, Pulinilkunnil T, Kienesberger PC.

Endocrinology. 2017 Apr 1;158(4):791-803. doi: 10.1210/en.2017-00035.

PMID:
28324037
13.

Autophagic dysregulation in doxorubicin cardiomyopathy.

Bartlett JJ, Trivedi PC, Pulinilkunnil T.

J Mol Cell Cardiol. 2017 Mar;104:1-8. doi: 10.1016/j.yjmcc.2017.01.007. Epub 2017 Jan 17. Review.

PMID:
28108310
14.

Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes.

Zhang D, Wang F, Lal N, Chiu AP, Wan A, Jia J, Bierende D, Flibotte S, Sinha S, Asadi A, Hu X, Taghizadeh F, Pulinilkunnil T, Nislow C, Vlodavsky I, Johnson JD, Kieffer TJ, Hussein B, Rodrigues B.

Diabetes. 2017 Jan;66(1):45-57. doi: 10.2337/db16-0761. Epub 2016 Oct 7.

15.

Doxorubicin impairs cardiomyocyte viability by suppressing transcription factor EB expression and disrupting autophagy.

Bartlett JJ, Trivedi PC, Yeung P, Kienesberger PC, Pulinilkunnil T.

Biochem J. 2016 Nov 1;473(21):3769-3789. Epub 2016 Aug 3.

PMID:
27487838
16.

Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes.

Trivedi PC, Bartlett JJ, Perez LJ, Brunt KR, Legare JF, Hassan A, Kienesberger PC, Pulinilkunnil T.

Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1893-1910. doi: 10.1016/j.bbalip.2016.09.004. Epub 2016 Sep 9.

PMID:
27620487
17.

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice.

Schoiswohl G, Stefanovic-Racic M, Menke MN, Wills RC, Surlow BA, Basantani MK, Sitnick MT, Cai L, Yazbeck CF, Stolz DB, Pulinilkunnil T, O'Doherty RM, Kershaw EE.

Endocrinology. 2015 Oct;156(10):3610-24. doi: 10.1210/en.2015-1322. Epub 2015 Jul 21.

18.

Skeletal muscle ACC2 S212 phosphorylation is not required for the control of fatty acid oxidation during exercise.

O'Neill HM, Lally JS, Galic S, Pulinilkunnil T, Ford RJ, Dyck JR, van Denderen BJ, Kemp BE, Steinberg GR.

Physiol Rep. 2015 Jul;3(7). pii: e12444. doi: 10.14814/phy2.12444.

19.

Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice.

Dubé JJ, Sitnick MT, Schoiswohl G, Wills RC, Basantani MK, Cai L, Pulinilkunnil T, Kershaw EE.

Am J Physiol Endocrinol Metab. 2015 May 15;308(10):E879-90. doi: 10.1152/ajpendo.00530.2014. Epub 2015 Mar 17.

20.

Holiday reading. Diving into the ice bucket challenge.

Adisesh A, Melville S, Pulinilkunnil T, Lutchmedial S, Brunt KR.

CMAJ. 2014 Dec 9;186(18):1404-5. doi: 10.1503/cmaj.141241. No abstract available.

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