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Lupus. 2012 Sep;21(10):1128-30. doi: 10.1177/0961203312444174. Epub 2012 Mar 29.

Psychiatric manifestations in patients with dysautonomy associated with systemic lupus erythematosus.

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Rheumatology Unit, Fundación Valle del Lili, Colombia - ICESI University, Colombia.


The psychiatric manifestations of three patients with systemic lupus erythematosus (SLE) and neuropathic dysautonomic processes are described. All patients had a severe form of SLE with neurological, renal, articular, pulmonary or haematological manifestations. All three have two types of psychiatric manifestations: (1) a chronic and progressive depression and (2) a complex dissociative disorder during the acute episodes of postural hypotension. A provocative test with SPECT with 99mTc-HmPAO to be done during the episode of orthostatic hypotension may contribute to clinical assessment of complex changes in cerebral regional perfusion.

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