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Stud Health Technol Inform. 2017;243:100-104.

Proof-of-Concept Integration of Heterogeneous Biobank IT Infrastructures into a Hybrid Biobanking Network.

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Medical Informatics, Univ. of Erlangen-Nürnberg, Erlangen, Germany.
UGMLC, German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.
Medical Informatics Group, University Hospital Frankfurt, Frankfurt, Germany.
German Cancer Consortium (DKTK), partner site Frankfurt; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
Clinical Cancer Registry, Charité Comprehensive Cancer Center, Berlin, Germany.
Institute of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany; and Central Biobank Charité (ZeBanC), Berlin, Germany.
Medical Informatics in Translational Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.


Cross-institutional biobank networks hold the promise of supporting medicine by enabling the exchange of associated samples for research purposes. Various initiatives, such as BBMRI-ERIC and German Biobank Node (GBN), aim to interconnect biobanks for enabling the compilation of joint biomaterial collections. However, building software platforms to facilitate such collaboration is challenging due to the heterogeneity of existing biobank IT infrastructures and the necessary efforts for installing and maintaining additional software components. As a remedy, this paper presents the concept of a hybrid network for interconnecting already existing software components commonly found in biobanks and a proof-of-concept implementation of two prototypes involving four biobanks of the German Biobank Node. Here we demonstrate the successful bridging of two IT systems found in many German biobanks - Samply and i2b2.


German Biobank Node; Translational medical research; biobank network; cohort identification; federated queries

[Indexed for MEDLINE]

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