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High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol.
Barker EL, Perlman MA, Adkins EM, Houlihan WJ, Pristupa ZB, Niznik HB, Blakely RD. Barker EL, et al. Among authors: pristupa zb. J Biol Chem. 1998 Jul 31;273(31):19459-68. doi: 10.1074/jbc.273.31.19459. J Biol Chem. 1998. PMID: 9677366 Free article.
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