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Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft.
FEBS J. 2010 Oct;277(20):4338-45. doi: 10.1111/j.1742-4658.2010.07824.x. Epub 2010 Sep 22.
FEBS J. 2010.
PMID: 20860624
Free article.
Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis.
Pozgan U, Caglic D, Rozman B, Nagase H, Turk V, Turk B.
Pozgan U, et al.
Biol Chem. 2010 May;391(5):571-9. doi: 10.1515/BC.2010.035.
Biol Chem. 2010.
PMID: 20180636
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Autocatalytic processing of procathepsin B is triggered by proenzyme activity.
Pungercar JR, Caglic D, Sajid M, Dolinar M, Vasiljeva O, Pozgan U, Turk D, Bogyo M, Turk V, Turk B.
Pungercar JR, et al. Among authors: pozgan u.
FEBS J. 2009 Feb;276(3):660-8. doi: 10.1111/j.1742-4658.2008.06815.x.
FEBS J. 2009.
PMID: 19143833
Free PMC article.
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