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Items: 1 to 20 of 36


Antiepileptic action of c-Jun N-terminal kinase (JNK) inhibition in an animal model of temporal lobe epilepsy.

Tai TY, Warner LN, Jones TD, Jung S, Concepcion FA, Skyrud DW, Fender J, Liu Y, Williams AD, Neumaier JF, D'Ambrosio R, Poolos NP.

Neuroscience. 2017 May 4;349:35-47. doi: 10.1016/j.neuroscience.2017.02.024. Epub 2017 Feb 22.


Association between antiepileptic drug dose and long-term response in patients with refractory epilepsy.

Poolos NP, Castagna CE, Williams S, Miller AB, Story TJ.

Epilepsy Behav. 2017 Apr;69:59-68. doi: 10.1016/j.yebeh.2016.10.010. Epub 2017 Feb 23.


Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in Epilepsy.

Brennan GP, Baram TZ, Poolos NP.

Cold Spring Harb Perspect Med. 2016 Mar 1;6(3):a022384. doi: 10.1101/cshperspect.a022384. Review.


Stopping epileptogenesis dead in its trks.

Poolos NP.

Epilepsy Curr. 2014 May;14(3):163-4. doi: 10.5698/1535-7597-14.3.163. No abstract available.


Dendritic ion channelopathy in acquired epilepsy.

Poolos NP, Johnston D.

Epilepsia. 2012 Dec;53 Suppl 9:32-40. doi: 10.1111/epi.12033. Review.


Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Ion Channelopathy in Epilepsy.

Poolos NP.

In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.


Dephosphorylation proves detrimental to GABAergic inhibition.

Poolos NP.

Epilepsy Curr. 2012 Jan;12(1):22-3. doi: 10.5698/1535-7511-12.1.22. No abstract available.


Identification of new epilepsy treatments: issues in preclinical methodology.

Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J Jr, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M; American Epilepsy Society Basic Science Committee And The International League Against Epilepsy Working Group On Recommendations For Preclinical Epilepsy Drug Discovery.

Epilepsia. 2012 Mar;53(3):571-82. doi: 10.1111/j.1528-1167.2011.03391.x. Epub 2012 Jan 31. Review.


Comparative efficacy of combination drug therapy in refractory epilepsy.

Poolos NP, Warner LN, Humphreys SZ, Williams S.

Neurology. 2012 Jan 3;78(1):62-8. doi: 10.1212/WNL.0b013e31823ed0dd. Epub 2011 Dec 14.


Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticus.

Jung S, Warner LN, Pitsch J, Becker AJ, Poolos NP.

J Neurosci. 2011 Oct 5;31(40):14291-5. doi: 10.1523/JNEUROSCI.1148-11.2011.


Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling.

Jung S, Bullis JB, Lau IH, Jones TD, Warner LN, Poolos NP.

J Neurosci. 2010 May 12;30(19):6678-88. doi: 10.1523/JNEUROSCI.1290-10.2010.


Genetic loss of HCN1 channels is exciting, but is it epileptic?

Poolos NP.

Epilepsy Curr. 2010 Mar;10(2):49-51. doi: 10.1111/j.1535-7511.2009.01352.x. No abstract available.


T-channels: short-term up-regulation causes long-term consequences in epilepsy.

Poolos NP.

Epilepsy Curr. 2009 Jul-Aug;9(4):121-3. doi: 10.1111/j.1535-7511.2009.01313.x. No abstract available.


Seeing the forest and the trees: dendritic injury after status epilepticus.

Poolos NP.

Epilepsy Curr. 2008 May-Jun;8(3):77-9. doi: 10.1111/j.1535-7511.2008.00244.x. No abstract available.


Patch-clamp recording from neuronal dendrites.

Poolos NP, Jones TD.

Curr Protoc Neurosci. 2004 Nov;Chapter 6:Unit 6.19. doi: 10.1002/0471142301.ns0619s29.


Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy.

Jung S, Jones TD, Lugo JN Jr, Sheerin AH, Miller JW, D'Ambrosio R, Anderson AE, Poolos NP.

J Neurosci. 2007 Nov 21;27(47):13012-21.


Position statement on the coverage of anticonvulsant drugs for the treatment of epilepsy: what's the problem with generic antiepileptic drugs? A call to action.

Miller JW, Anderson GD, Doherty MJ, Poolos NP.

Neurology. 2007 Oct 30;69(18):1806-8. No abstract available.


Glutamate receptors: finally fingered in inherited epilepsy?

Poolos NP.

Epilepsy Curr. 2007 Jul-Aug;7(4):110-1. No abstract available.


Reversed somatodendritic I(h) gradient in a class of rat hippocampal neurons with pyramidal morphology.

Bullis JB, Jones TD, Poolos NP.

J Physiol. 2007 Mar 1;579(Pt 2):431-43. Epub 2006 Dec 21.

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