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The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance.
Joshi SK, Nechiporuk T, Bottomly D, Piehowski PD, Reisz JA, Pittsenbarger J, Kaempf A, Gosline SJC, Wang YT, Hansen JR, Gritsenko MA, Hutchinson C, Weitz KK, Moon J, Cendali F, Fillmore TL, Tsai CF, Schepmoes AA, Shi T, Arshad OA, McDermott JE, Babur O, Watanabe-Smith K, Demir E, D'Alessandro A, Liu T, Tognon CE, Tyner JW, McWeeney SK, Rodland KD, Druker BJ, Traer E. Joshi SK, et al. Among authors: pittsenbarger j. Cancer Cell. 2021 Jul 12;39(7):999-1014.e8. doi: 10.1016/j.ccell.2021.06.003. Epub 2021 Jun 24. Cancer Cell. 2021. PMID: 34171263 Free PMC article.
HIF1 and ID1 Interplay Confers Adaptive Survival to HIF1α-Inhibition.
Geng H, Ko HK, Pittsenbarger J, Harvey CT, Xue C, Liu Q, Wiens S, Kachhap SK, Beer TM, Qian DZ. Geng H, et al. Among authors: pittsenbarger j. Front Cell Dev Biol. 2021 Nov 8;9:724059. doi: 10.3389/fcell.2021.724059. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34820369 Free PMC article.
ID1 enhances docetaxel cytotoxicity in prostate cancer cells through inhibition of p21.
Geng H, Rademacher BL, Pittsenbarger J, Huang CY, Harvey CT, Lafortune MC, Myrthue A, Garzotto M, Nelson PS, Beer TM, Qian DZ. Geng H, et al. Among authors: pittsenbarger j. Cancer Res. 2010 Apr 15;70(8):3239-48. doi: 10.1158/0008-5472.CAN-09-3186. Epub 2010 Apr 13. Cancer Res. 2010. PMID: 20388787 Free PMC article.