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Items: 1 to 20 of 170

1.

Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis.

Immonen R, Smith G, Brady RD, Wright D, Johnston L, Harris NG, Manninen E, Salo R, Branch C, Duncan D, Cabeen R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Shultz SR, Andrade P, Puhakka N, Staba RJ, O'Brien TJ, Toga AW, Pitkänen A, Gröhn O.

Epilepsy Res. 2019 Jan 7;150:46-57. doi: 10.1016/j.eplepsyres.2019.01.001. [Epub ahead of print]

PMID:
30641351
2.

Analytic Tools for Post-traumatic Epileptogenesis Biomarker Search in Multimodal Dataset of an Animal Model and Human Patients.

Duncan D, Barisano G, Cabeen R, Sepehrband F, Garner R, Braimah A, Vespa P, Pitkänen A, Law M, Toga AW.

Front Neuroinform. 2018 Dec 20;12:86. doi: 10.3389/fninf.2018.00086. eCollection 2018.

3.

Informatics tools to assess the success of procedural harmonization in preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis.

Ciszek R, Ndode-Ekane XE, Gomez CS, Casillas-Espinosa PM, Ali I, Smith G, Puhakka N, Lapinlampi N, Andrade P, Kamnaksh A, Immonen R, Paananen T, Hudson MR, Brady RD, Shultz SR, O'Brien TJ, Staba RJ, Tohka J, Pitkänen A.

Epilepsy Res. 2018 Dec 27;150:17-26. doi: 10.1016/j.eplepsyres.2018.12.010. [Epub ahead of print]

PMID:
30605864
4.

Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs.

Karttunen J, Heiskanen M, Navarro-Ferrandis V, Das Gupta S, Lipponen A, Puhakka N, Rilla K, Koistinen A, Pitkänen A.

J Extracell Vesicles. 2018 Dec 18;8(1):1555410. doi: 10.1080/20013078.2018.1555410. eCollection 2019.

5.

Harmonization of pipeline for preclinical multicenter plasma protein and miRNA biomarker discovery in a rat model of post-traumatic epileptogenesis.

Kamnaksh A, Puhakka N, Ali I, Smith G, Aniceto R, McCullough J, Das Gupta S, Ndode-Ekane XE, Brady R, Casillas-Espinosa P, Hudson M, Santana-Gomez C, Immonen R, Abreu PA, Jones N, Shultz S, Staba RJ, O'Brien TJ, Agoston D, Pitkänen A.

Epilepsy Res. 2019 Jan;149:92-101. doi: 10.1016/j.eplepsyres.2018.11.009. Epub 2018 Nov 26.

PMID:
30553097
6.

Acute non-convulsive status epilepticus after experimental traumatic brain injury in rats.

Andrade P, Banuelos-Cabrera I, Lapinlampi N, Paananen T, Ciszek R, Ndode-Ekane XE, Pitkanen A.

J Neurotrauma. 2018 Dec 13. doi: 10.1089/neu.2018.6107. [Epub ahead of print]

PMID:
30543155
7.

Common data elements (CDEs) for preclinical epilepsy research: Introduction to CDEs and description of core CDEs. A TASK3 report of the ILAE/AES joint translational task force.

Harte-Hargrove LC, Galanopoulou AS, French JA, Pitkänen A, Whittemore V, Scharfman HE.

Epilepsia Open. 2018 Jul 26;3(Suppl Suppl 1):13-23. doi: 10.1002/epi4.12234. eCollection 2018 Nov.

8.

Preclinical common data elements (CDEs) for epilepsy: A joint ILAE/AES and NINDS translational initiative.

Scharfman HE, Galanopoulou AS, French JA, Pitkänen A, Whittemore V, Harte-Hargrove LC.

Epilepsia Open. 2018 Jul 18;3(Suppl Suppl 1):9-12. doi: 10.1002/epi4.12235. eCollection 2018 Nov. No abstract available.

9.

A web-based application for generating 2D-unfolded cortical maps to analyze the location and extent of cortical lesions following traumatic brain injury in adult rats.

Andrade P, Ciszek R, Pitkänen A, Ndode-Ekane XE.

J Neurosci Methods. 2018 Oct 1;308:330-336. doi: 10.1016/j.jneumeth.2018.08.028. Epub 2018 Sep 5.

PMID:
30194043
10.

miR-124-3p is a chronic regulator of gene expression after brain injury.

Vuokila N, Lukasiuk K, Bot AM, van Vliet EA, Aronica E, Pitkänen A, Puhakka N.

Cell Mol Life Sci. 2018 Dec;75(24):4557-4581. doi: 10.1007/s00018-018-2911-z. Epub 2018 Aug 28.

PMID:
30155647
11.

The epilepsy bioinformatics study for anti-epileptogenic therapy (EpiBioS4Rx) clinical biomarker: Study design and protocol.

Vespa PM, Shrestha V, Abend N, Agoston D, Au A, Bell MJ, Bleck TP, Blanco MB, Claassen J, Diaz-Arrastia R, Duncan D, Ellingson B, Foreman B, Gilmore EJ, Hirsch L, Hunn M, Kamnaksh A, McArthur D, Morokoff A, O'Brien T, O'Phelan K, Robertson CL, Rosenthal E, Staba R, Toga A, Willyerd FA, Zimmermann L, Yam E, Martinez S, Real C, Engel J Jr; EpiBioS4Rx Study Group, Agoston D, Au A, Bell MJ, Bleck Thomas P, Branch C, Buitrago Blanco M, Bullock R, Burrows BT, Claassen J, Clarke R, Cloyd J, Coles L, Crawford K, Diaz-Arrastia R, Duncan D, Ellingson B, Engel J, Foreman B, Galanopoulou A, Gilmore E, Grohn O, Harris N, Hartings J, Lawrence H, Hunn M, Jette N, Johnston L, Jones N, Kanner A, McArthur D, Monti M, Morokoff A, Moshe S, Mowrey W, O'Brien T, O'Phelan K, Pitkanen A, Raman R, Robertson C, Rosenthal E, Shultz S, Snutch T, Staba R, Toga A, Van Horn J, Vespa P, Willyerd F, Zimmermann L.

Neurobiol Dis. 2018 Jul 23. pii: S0969-9961(18)30311-5. doi: 10.1016/j.nbd.2018.07.025. [Epub ahead of print] Review.

PMID:
30048805
12.

Detection of Hyperexcitability by Functional Magnetic Resonance Imaging after Experimental Traumatic Brain Injury.

Huttunen JK, Airaksinen AM, Barba C, Colicchio G, Niskanen JP, Shatillo A, Sierra Lopez A, Ndode-Ekane XE, Pitkänen A, Gröhn OH.

J Neurotrauma. 2018 Nov 15;35(22):2708-2717. doi: 10.1089/neu.2017.5308. Epub 2018 Sep 27.

PMID:
30019618
13.

Algorithm for automatic detection of spontaneous seizures in rats with post-traumatic epilepsy.

Andrade P, Paananen T, Ciszek R, Lapinlampi N, Pitkänen A.

J Neurosci Methods. 2018 Sep 1;307:37-45. doi: 10.1016/j.jneumeth.2018.06.015. Epub 2018 Jun 21.

PMID:
29936072
14.

T-cell infiltration into the perilesional cortex is long-lasting and associates with poor somatomotor recovery after experimental traumatic brain injury.

Ndode-Ekane XE, Matthiesen L, Bañuelos-Cabrera I, Palminha CAP, Pitkänen A.

Restor Neurol Neurosci. 2018;36(4):485-501. doi: 10.3233/RNN-170811.

PMID:
29889085
15.

Big data sharing and analysis to advance research in post-traumatic epilepsy.

Duncan D, Vespa P, Pitkänen A, Braimah A, Lapinlampi N, Toga AW.

Neurobiol Dis. 2018 Jun 1. pii: S0969-9961(18)30170-0. doi: 10.1016/j.nbd.2018.05.026. [Epub ahead of print] Review.

PMID:
29864492
16.

Early seizures and temporal lobe trauma predict post-traumatic epilepsy: A longitudinal study.

Tubi MA, Lutkenhoff E, Blanco MB, McArthur D, Villablanca P, Ellingson B, Diaz-Arrastia R, Van Ness P, Real C, Shrestha V, Engel J Jr, Vespa PM; EpiBioS4Rx Study Group Investigators, Agoston D, Au A, Bell MJ, Bleck T, Branch C, Buitrago Blanco M, Bullock R, Burrows BT, Claassen J, Clarke R, Cloyd J, Coles L, Crawford K, Diaz-Arrastia R, Duncan D, Ellingson B, Engel J, Foreman B, Galanopoulou A, Gilmore E, Olli G, Harris N, Hartings J, Lawrence H, Hunn M, Jette N, Johnston L, Jones N, Kanner A, McArthur D, Monti M, Morokoff A, Moshe S, Mowrey W, O'Brien T, O'Phelan K, Pitkanen A, Raman R, Robertson C, Rosenthal E, Shultz S, Snutch T, Staba R, Toga A, Van Horn J, Vespa P, Willyerd F, Zimmermann L.

Neurobiol Dis. 2018 Jun 1. pii: S0969-9961(18)30152-9. doi: 10.1016/j.nbd.2018.05.014. [Epub ahead of print] Review.

PMID:
29859872
17.

Epilepsy biomarkers - Toward etiology and pathology specificity.

Pitkänen A, Ekolle Ndode-Ekane X, Lapinlampi N, Puhakka N.

Neurobiol Dis. 2018 May 18. pii: S0969-9961(18)30145-1. doi: 10.1016/j.nbd.2018.05.007. [Epub ahead of print] Review.

PMID:
29782966
18.

Sushi repeat-containing protein X-linked 2: A novel phylogenetically conserved hypothalamo-pituitary protein.

Anwer M, Bolkvadze T, Ndode-Ekane XE, Puhakka N, Rauramaa T, Leinonen V, van Vliet EA, Swaab DF, Haapasalo A, Leskelä S, Bister N, Malm T, Carlson S, Aronica E, Pitkänen A.

J Comp Neurol. 2018 Aug 1;526(11):1806-1819. doi: 10.1002/cne.24449. Epub 2018 May 1.

PMID:
29663392
19.

Epilepsy in neuropathologically verified Alzheimer's disease.

Rauramaa T, Saxlin A, Lohvansuu K, Alafuzoff I, Pitkänen A, Soininen H.

Seizure. 2018 May;58:9-12. doi: 10.1016/j.seizure.2018.03.014. Epub 2018 Mar 16.

PMID:
29602145
20.

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury.

Lipponen A, El-Osta A, Kaspi A, Ziemann M, Khurana I, Kn H, Navarro-Ferrandis V, Puhakka N, Paananen J, Pitkänen A.

Acta Neuropathol Commun. 2018 Feb 27;6(1):17. doi: 10.1186/s40478-018-0519-z.

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