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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2001 1
2005 1
2006 1
2008 1
2009 3
2011 4
2012 4
2013 5
2014 1
2015 1
2016 2
2017 3
2018 6
2019 1
2020 4
2021 3
2022 1
2023 3
2024 0

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44 results

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Page 1
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
Griffith DA, Edmonds DJ, Fortin JP, Kalgutkar AS, Kuzmiski JB, Loria PM, Saxena AR, Bagley SW, Buckeridge C, Curto JM, Derksen DR, Dias JM, Griffor MC, Han S, Jackson VM, Landis MS, Lettiere D, Limberakis C, Liu Y, Mathiowetz AM, Patel JC, Piotrowski DW, Price DA, Ruggeri RB, Tess DA. Griffith DA, et al. Among authors: piotrowski dw. J Med Chem. 2022 Jun 23;65(12):8208-8226. doi: 10.1021/acs.jmedchem.1c01856. Epub 2022 Jun 1. J Med Chem. 2022. PMID: 35647711 Free PMC article.
Cycloisomerization of Olefins in Water.
Matos JLM, Green SA, Chun Y, Dang VQ, Dushin RG, Richardson P, Chen JS, Piotrowski DW, Paegel BM, Shenvi RA. Matos JLM, et al. Among authors: piotrowski dw. Angew Chem Int Ed Engl. 2020 Jul 27;59(31):12998-13003. doi: 10.1002/anie.202003948. Epub 2020 May 28. Angew Chem Int Ed Engl. 2020. PMID: 32285542 Free PMC article.
Merging C(sp3)-H activation with DNA-encoding.
Fan Z, Zhao S, Liu T, Shen PX, Cui ZN, Zhuang Z, Shao Q, Chen JS, Ratnayake AS, Flanagan ME, Kölmel DK, Piotrowski DW, Richardson P, Yu JQ. Fan Z, et al. Among authors: piotrowski dw. Chem Sci. 2020 Sep 7;11(45):12282-12288. doi: 10.1039/d0sc03935g. Chem Sci. 2020. PMID: 34094436 Free PMC article.
RASS-Enabled S/P-C and S-N Bond Formation for DEL Synthesis.
Flood DT, Zhang X, Fu X, Zhao Z, Asai S, Sanchez BB, Sturgell EJ, Vantourout JC, Richardson P, Flanagan ME, Piotrowski DW, Kölmel DK, Wan J, Tsai MH, Chen JS, Baran PS, Dawson PE. Flood DT, et al. Among authors: piotrowski dw. Angew Chem Int Ed Engl. 2020 May 4;59(19):7377-7383. doi: 10.1002/anie.201915493. Epub 2020 Mar 11. Angew Chem Int Ed Engl. 2020. PMID: 32050046 Free PMC article.
6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptor.
Aspnes GE, Bagley SW, Coffey SB, Conn EL, Curto JM, Edmonds DJ, Genovino J, Griffith DA, Ingle G, Jiao W, Limberakis C, Mathiowetz AM, Piotrowski DW, Rose CR, Ruggeri RB, Wei L. Aspnes GE, et al. Among authors: piotrowski dw. Bioorg Med Chem Lett. 2023 Oct 1;94:129454. doi: 10.1016/j.bmcl.2023.129454. Epub 2023 Aug 15. Bioorg Med Chem Lett. 2023. PMID: 37591316
Small molecule inhibitors of PCSK9. SAR investigations of head and amine groups.
Aspnes GE, Coffey SB, Darout E, Dechert-Schmitt AM, Dullea RG, Kamlet AS, Limberakis C, Londregan AT, McClure KF, Menhaji-Klotz E, Piotrowski DW, Polivkova J, Raymer B, Ruggeri RB, Salatto CT, Tu M, Wei L, Xiao J. Aspnes GE, et al. Among authors: piotrowski dw. Bioorg Med Chem Lett. 2023 Aug 15;92:129394. doi: 10.1016/j.bmcl.2023.129394. Epub 2023 Jun 26. Bioorg Med Chem Lett. 2023. PMID: 37379958
Positive allosteric modulators of the α7 nicotinic acetylcholine receptor: SAR investigation around PNU-120596.
Acker BA, Badescu VO, Berkenpas MB, Groppi VE, Hajós M, Higdon NR, Hurst RS, Jon Jacobsen E, Margolis BJ, McWhorter WW, Myers JK, Piotrowski DW, Rogers BN, Sarapa D, Vetman TN, Walker DP, Wall TM, Wilhite DM, Wishka DG, Xu W, Yates KM. Acker BA, et al. Among authors: piotrowski dw. Bioorg Med Chem Lett. 2023 Sep 1;93:129433. doi: 10.1016/j.bmcl.2023.129433. Epub 2023 Aug 7. Bioorg Med Chem Lett. 2023. PMID: 37557923
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease.
Gopalsamy A, Aulabaugh AE, Barakat A, Beaumont KC, Cabral S, Canterbury DP, Casimiro-Garcia A, Chang JS, Chen MZ, Choi C, Dow RL, Fadeyi OO, Feng X, France SP, Howard RM, Janz JM, Jasti J, Jasuja R, Jones LH, King-Ahmad A, Knee KM, Kohrt JT, Limberakis C, Liras S, Martinez CA, McClure KF, Narayanan A, Narula J, Novak JJ, O'Connell TN, Parikh MD, Piotrowski DW, Plotnikova O, Robinson RP, Sahasrabudhe PV, Sharma R, Thuma BA, Vasa D, Wei L, Wenzel AZ, Withka JM, Xiao J, Yayla HG. Gopalsamy A, et al. Among authors: piotrowski dw. J Med Chem. 2021 Jan 14;64(1):326-342. doi: 10.1021/acs.jmedchem.0c01518. Epub 2020 Dec 24. J Med Chem. 2021. PMID: 33356244
44 results