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Items: 1 to 20 of 84

1.

Subcellular organization of UBE3A in human cerebral cortex.

Burette AC, Judson MC, Li AN, Chang EF, Seeley WW, Philpot BD, Weinberg RJ.

Mol Autism. 2018 Oct 19;9:54. doi: 10.1186/s13229-018-0238-0. eCollection 2018.

2.

Ube3a reinstatement mitigates epileptogenesis in Angelman syndrome model mice.

Gu B, Carstens KE, Judson MC, Dalton KA, Rougié M, Clark EP, Dudek SM, Philpot BD.

J Clin Invest. 2018 Nov 19. pii: 120816. doi: 10.1172/JCI120816. [Epub ahead of print]

3.

Characterization and structure-activity relationships of indenoisoquinoline-derived topoisomerase I inhibitors in unsilencing the dormant Ube3a gene associated with Angelman syndrome.

Lee HM, Clark EP, Kuijer MB, Cushman M, Pommier Y, Philpot BD.

Mol Autism. 2018 Aug 17;9:45. doi: 10.1186/s13229-018-0228-2. eCollection 2018.

4.

The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility.

Wall MJ, Collins DR, Chery SL, Allen ZD, Pastuzyn ED, George AJ, Nikolova VD, Moy SS, Philpot BD, Shepherd JD, Müller J, Ehlers MD, Mabb AM, Corrêa SAL.

Neuron. 2018 Jun 27;98(6):1124-1132.e7. doi: 10.1016/j.neuron.2018.05.012. Epub 2018 May 31.

5.

Abnormal coherence and sleep composition in children with Angelman syndrome: a retrospective EEG study.

den Bakker H, Sidorov MS, Fan Z, Lee DJ, Bird LM, Chu CJ, Philpot BD.

Mol Autism. 2018 Apr 27;9:32. doi: 10.1186/s13229-018-0214-8. eCollection 2018.

6.

Enhanced Operant Extinction and Prefrontal Excitability in a Mouse Model of Angelman Syndrome.

Sidorov MS, Judson MC, Kim H, Rougie M, Ferrer AI, Nikolova VD, Riddick NV, Moy SS, Philpot BD.

J Neurosci. 2018 Mar 14;38(11):2671-2682. doi: 10.1523/JNEUROSCI.2828-17.2018. Epub 2018 Feb 5.

7.

Common Pathophysiology in Multiple Mouse Models of Pitt-Hopkins Syndrome.

Thaxton C, Kloth AD, Clark EP, Moy SS, Chitwood RA, Philpot BD.

J Neurosci. 2018 Jan 24;38(4):918-936. doi: 10.1523/JNEUROSCI.1305-17.2017. Epub 2017 Dec 8.

8.

Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling.

Nagendran T, Larsen RS, Bigler RL, Frost SB, Philpot BD, Nudo RJ, Taylor AM.

Nat Commun. 2017 Sep 20;8(1):625. doi: 10.1038/s41467-017-00652-y.

9.

Enhanced Nociception in Angelman Syndrome Model Mice.

McCoy ES, Taylor-Blake B, Aita M, Simon JM, Philpot BD, Zylka MJ.

J Neurosci. 2017 Oct 18;37(42):10230-10239. doi: 10.1523/JNEUROSCI.1018-17.2017. Epub 2017 Sep 20.

10.

Erratum to: Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis.

Sidorov MS, Deck GM, Dolatshahi M, Thibert RL, Bird LM, Chu CJ, Philpot BD.

J Neurodev Disord. 2017 Jul 17;9:30. doi: 10.1186/s11689-017-9210-0. eCollection 2017.

11.

Decreased Axon Caliber Underlies Loss of Fiber Tract Integrity, Disproportional Reductions in White Matter Volume, and Microcephaly in Angelman Syndrome Model Mice.

Judson MC, Burette AC, Thaxton CL, Pribisko AL, Shen MD, Rumple AM, Del Cid WA, Paniagua B, Styner M, Weinberg RJ, Philpot BD.

J Neurosci. 2017 Aug 2;37(31):7347-7361. doi: 10.1523/JNEUROSCI.0037-17.2017. Epub 2017 Jun 29.

12.

Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis.

Sidorov MS, Deck GM, Dolatshahi M, Thibert RL, Bird LM, Chu CJ, Philpot BD.

J Neurodev Disord. 2017 May 8;9:17. doi: 10.1186/s11689-017-9195-8. eCollection 2017. Erratum in: J Neurodev Disord. 2017 Jul 17;9:30.

13.

Ube3a loss increases excitability and blunts orientation tuning in the visual cortex of Angelman syndrome model mice.

Wallace ML, van Woerden GM, Elgersma Y, Smith SL, Philpot BD.

J Neurophysiol. 2017 Jul 1;118(1):634-646. doi: 10.1152/jn.00618.2016. Epub 2017 May 3.

14.

Subcellular organization of UBE3A in neurons.

Burette AC, Judson MC, Burette S, Phend KD, Philpot BD, Weinberg RJ.

J Comp Neurol. 2017 Feb 1;525(2):233-251. doi: 10.1002/cne.24063. Epub 2016 Jul 11.

15.

Persistent neuronal Ube3a expression in the suprachiasmatic nucleus of Angelman syndrome model mice.

Jones KA, Han JE, DeBruyne JP, Philpot BD.

Sci Rep. 2016 Jun 16;6:28238. doi: 10.1038/srep28238.

16.

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

Mabb AM, Simon JM, King IF, Lee HM, An LK, Philpot BD, Zylka MJ.

PLoS One. 2016 May 27;11(5):e0156439. doi: 10.1371/journal.pone.0156439. eCollection 2016.

17.

Maternal Loss of Ube3a Impairs Experience-Driven Dendritic Spine Maintenance in the Developing Visual Cortex.

Kim H, Kunz PA, Mooney R, Philpot BD, Smith SL.

J Neurosci. 2016 Apr 27;36(17):4888-94. doi: 10.1523/JNEUROSCI.4204-15.2016.

18.

GABAergic Neuron-Specific Loss of Ube3a Causes Angelman Syndrome-Like EEG Abnormalities and Enhances Seizure Susceptibility.

Judson MC, Wallace ML, Sidorov MS, Burette AC, Gu B, van Woerden GM, King IF, Han JE, Zylka MJ, Elgersma Y, Weinberg RJ, Philpot BD.

Neuron. 2016 Apr 6;90(1):56-69. doi: 10.1016/j.neuron.2016.02.040. Epub 2016 Mar 24.

19.

Loss of UBE3A from TH-expressing neurons suppresses GABA co-release and enhances VTA-NAc optical self-stimulation.

Berrios J, Stamatakis AM, Kantak PA, McElligott ZA, Judson MC, Aita M, Rougie M, Stuber GD, Philpot BD.

Nat Commun. 2016 Feb 12;7:10702. doi: 10.1038/ncomms10702.

20.

Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex.

Xing L, Larsen RS, Bjorklund GR, Li X, Wu Y, Philpot BD, Snider WD, Newbern JM.

Elife. 2016 Feb 5;5. pii: e11123. doi: 10.7554/eLife.11123.

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