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Peripheral blood monocytes reveal an activated phenotype in pediatric uveitis.
Walscheid K, Neekamp L, Heiligenhaus A, Weinhage T, Holzinger D, Heinz C, Kasper M, Foell D. Walscheid K, et al. Clin Immunol. 2018 May;190:84-88. doi: 10.1016/j.clim.2017.09.014. Epub 2017 Sep 18. Clin Immunol. 2018. PMID: 28923439
OBJECTIVE: To characterize peripheral blood monocytes in uveitis associated with juvenile idiopathic arthritis (JIAU). METHODS: Peripheral blood monocytes from children with JIA (either with (n = 18) or without uveitis (n = …
OBJECTIVE: To characterize peripheral blood monocytes in uveitis associated with juvenile idiopathic arthritis ( …
Anti-TNF treatment corrects IFN-γ-dependent proinflammatory signatures in Blau syndrome patient-derived macrophages.
Kitagawa Y, Kawasaki Y, Yamasaki Y, Kambe N, Takei S, Saito MK. Kitagawa Y, et al. J Allergy Clin Immunol. 2022 Jan;149(1):176-188.e7. doi: 10.1016/j.jaci.2021.05.030. Epub 2021 Jun 24. J Allergy Clin Immunol. 2022. PMID: 34175136
OBJECTIVE: We aimed to elucidate the mechanisms of autoinflammation in patients with BS and to clarify how anti-TNF treatment controls the disease phenotype at the cellular level in clinical samples. METHODS: Macrophages were differentiated from monocytes of 7 BS pa …
OBJECTIVE: We aimed to elucidate the mechanisms of autoinflammation in patients with BS and to clarify how anti-TNF treatment controls the d …