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Items: 1 to 20 of 35


Human Cytomegalovirus miRNAs Regulate TGF-β to Mediate Myelosuppression while Maintaining Viral Latency in CD34+ Hematopoietic Progenitor Cells.

Hancock MH, Crawford LB, Pham AH, Mitchell J, Struthers HM, Yurochko AD, Caposio P, Nelson JA.

Cell Host Microbe. 2020 Jan 8;27(1):104-114.e4. doi: 10.1016/j.chom.2019.11.013. Epub 2019 Dec 19.


Characterization of a live-attenuated HCMV-based vaccine platform.

Caposio P, van den Worm S, Crawford L, Perez W, Kreklywich C, Gilbride RM, Hughes CM, Ventura AB, Ratts R, Marshall EE, Malouli D, Axthelm MK, Streblow D, Nelson JA, Picker LJ, Hansen SG, Früh K.

Sci Rep. 2019 Dec 17;9(1):19236. doi: 10.1038/s41598-019-55508-w.


Stabilization and formulation of a recombinant Human Cytomegalovirus vector for use as a candidate HIV-1 vaccine.

Kumru OS, Saleh-Birdjandi S, Antunez LR, Sayeed E, Robinson D, van den Worm S, Diemer GS, Perez W, Caposio P, Früh K, Joshi SB, Volkin DB.

Vaccine. 2019 Oct 16;37(44):6696-6706. doi: 10.1016/j.vaccine.2019.09.027. Epub 2019 Sep 20.


Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34+ Hematopoietic Progenitor Cells and Humanized NSG Mice.

Crawford LB, Caposio P, Kreklywich C, Pham AH, Hancock MH, Jones TA, Smith PP, Yurochko AD, Nelson JA, Streblow DN.

mBio. 2019 Aug 20;10(4). pii: e01889-19. doi: 10.1128/mBio.01889-19.


OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism.

E X, Meraner P, Lu P, Perreira JM, Aker AM, McDougall WM, Zhuge R, Chan GC, Gerstein RM, Caposio P, Yurochko AD, Brass AL, Kowalik TF.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7043-7052. doi: 10.1073/pnas.1814850116. Epub 2019 Mar 20.


Cancer Diagnostic and Predictive Biomarkers 2018.

Buonaguro FM, Caposio P, Tornesello ML, De Re V, Franco R.

Biomed Res Int. 2019 Jan 8;2019:3879015. doi: 10.1155/2019/3879015. eCollection 2019. No abstract available.


Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation.

Crawford LB, Kim JH, Collins-McMillen D, Lee BJ, Landais I, Held C, Nelson JA, Yurochko AD, Caposio P.

mBio. 2018 Apr 24;9(2). pii: e00682-18. doi: 10.1128/mBio.00682-18.


Cloning, Assembly, and Modification of the Primary Human Cytomegalovirus Isolate Toledo by Yeast-Based Transformation-Associated Recombination.

Vashee S, Stockwell TB, Alperovich N, Denisova EA, Gibson DG, Cady KC, Miller K, Kannan K, Malouli D, Crawford LB, Voorhies AA, Bruening E, Caposio P, Früh K.

mSphere. 2017 Oct 4;2(5). pii: e00331-17. doi: 10.1128/mSphereDirect.00331-17. eCollection 2017 Sep-Oct.


Human Cytomegalovirus Induces Cellular and Humoral Virus-specific Immune Responses in Humanized BLT Mice.

Crawford LB, Tempel R, Streblow DN, Kreklywich C, Smith P, Picker LJ, Nelson JA, Caposio P.

Sci Rep. 2017 Apr 20;7(1):937. doi: 10.1038/s41598-017-01051-5.


Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes.

Kim JH, Collins-McMillen D, Caposio P, Yurochko AD.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8819-24. doi: 10.1073/pnas.1604317113. Epub 2016 Jul 18.


Complex Interplay of the UL136 Isoforms Balances Cytomegalovirus Replication and Latency.

Caviness K, Bughio F, Crawford LB, Streblow DN, Nelson JA, Caposio P, Goodrum F.

mBio. 2016 Mar 1;7(2):e01986. doi: 10.1128/mBio.01986-15.


Humanized mouse models of human cytomegalovirus infection.

Crawford LB, Streblow DN, Hakki M, Nelson JA, Caposio P.

Curr Opin Virol. 2015 Aug;13:86-92. doi: 10.1016/j.coviro.2015.06.006. Epub 2015 Jun 25. Review.


A cytomegalovirus-based vaccine provides long-lasting protection against lethal Ebola virus challenge after a single dose.

Tsuda Y, Parkins CJ, Caposio P, Feldmann F, Botto S, Ball S, Messaoudi I, Cicin-Sain L, Feldmann H, Jarvis MA.

Vaccine. 2015 May 5;33(19):2261-2266. doi: 10.1016/j.vaccine.2015.03.029. Epub 2015 Mar 25.


Human cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesis.

MacManiman JD, Meuser A, Botto S, Smith PP, Liu F, Jarvis MA, Nelson JA, Caposio P.

mBio. 2014 Oct 28;5(6):e02035. doi: 10.1128/mBio.02035-14.


A cytomegalovirus-based vaccine expressing a single tumor-specific CD8+ T-cell epitope delays tumor growth in a murine model of prostate cancer.

Klyushnenkova EN, Kouiavskaia DV, Parkins CJ, Caposio P, Botto S, Alexander RB, Jarvis MA.

J Immunother. 2012 Jun;35(5):390-9. doi: 10.1097/CJI.0b013e3182585d50.


A single-dose cytomegalovirus-based vaccine encoding tetanus toxin fragment C induces sustained levels of protective tetanus toxin antibodies in mice.

Tierney R, Nakai T, Parkins CJ, Caposio P, Fairweather NF, Sesardic D, Jarvis MA.

Vaccine. 2012 Apr 26;30(20):3047-52. doi: 10.1016/j.vaccine.2012.02.043. Epub 2012 Mar 10.


A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection.

Umashankar M, Petrucelli A, Cicchini L, Caposio P, Kreklywich CN, Rak M, Bughio F, Goldman DC, Hamlin KL, Nelson JA, Fleming WH, Streblow DN, Goodrum F.

PLoS Pathog. 2011 Dec;7(12):e1002444. doi: 10.1371/journal.ppat.1002444. Epub 2011 Dec 29.


A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus.

Tsuda Y, Caposio P, Parkins CJ, Botto S, Messaoudi I, Cicin-Sain L, Feldmann H, Jarvis MA.

PLoS Negl Trop Dis. 2011 Aug;5(8):e1275. doi: 10.1371/journal.pntd.0001275. Epub 2011 Aug 9.


IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin.

Botto S, Streblow DN, DeFilippis V, White L, Kreklywich CN, Smith PP, Caposio P.

Blood. 2011 Jan 6;117(1):352-61. doi: 10.1182/blood-2010-06-291245. Epub 2010 Oct 7.


The role of cytomegalovirus in angiogenesis.

Caposio P, Orloff SL, Streblow DN.

Virus Res. 2011 May;157(2):204-11. doi: 10.1016/j.virusres.2010.09.011. Epub 2010 Oct 1. Review.

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