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Items: 1 to 20 of 28


Regulation of Glucose Handling by the Skeleton: Insights From Mouse and Human Studies.

Liu JM, Rosen CJ, Ducy P, Kousteni S, Karsenty G.

Diabetes. 2016 Nov;65(11):3225-3232. Review. No abstract available.


Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.

Ortuño MJ, Robinson ST, Subramanyam P, Paone R, Huang YY, Guo XE, Colecraft HM, Mann JJ, Ducy P.

Nat Med. 2016 Oct;22(10):1170-1179. doi: 10.1038/nm.4166. Epub 2016 Sep 5.


Lrp5 regulation of bone mass and serotonin synthesis in the gut.

Kode A, Obri A, Paone R, Kousteni S, Ducy P, Karsenty G.

Nat Med. 2014 Nov;20(11):1228-9. doi: 10.1038/nm.3698. No abstract available.


Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a.

Wei J, Hanna T, Suda N, Karsenty G, Ducy P.

Diabetes. 2014 Mar;63(3):1021-31. doi: 10.2337/db13-0887. Epub 2013 Sep 5.


Efficacy of serotonin inhibition in mouse models of bone loss.

Inose H, Zhou B, Yadav VK, Guo XE, Karsenty G, Ducy P.

J Bone Miner Res. 2011 Sep;26(9):2002-11. doi: 10.1002/jbmr.439.


Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice.

Ferron M, McKee MD, Levine RL, Ducy P, Karsenty G.

Bone. 2012 Feb;50(2):568-75. doi: 10.1016/j.bone.2011.04.017. Epub 2011 Apr 29.


Endocrine regulation of male fertility by the skeleton.

Oury F, Sumara G, Sumara O, Ferron M, Chang H, Smith CE, Hermo L, Suarez S, Roth BL, Ducy P, Karsenty G.

Cell. 2011 Mar 4;144(5):796-809. doi: 10.1016/j.cell.2011.02.004. Epub 2011 Feb 17.


5-HT and bone biology.

Ducy P.

Curr Opin Pharmacol. 2011 Feb;11(1):34-8. doi: 10.1016/j.coph.2011.01.007. Epub 2011 Feb 12. Review.


The two faces of serotonin in bone biology.

Ducy P, Karsenty G.

J Cell Biol. 2010 Oct 4;191(1):7-13. doi: 10.1083/jcb.201006123. Review.


Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.

Nistala H, Lee-Arteaga S, Smaldone S, Siciliano G, Carta L, Ono RN, Sengle G, Arteaga-Solis E, Levasseur R, Ducy P, Sakai LY, Karsenty G, Ramirez F.

J Cell Biol. 2010 Sep 20;190(6):1107-21. doi: 10.1083/jcb.201003089.


Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.

Ferron M, Wei J, Yoshizawa T, Del Fattore A, DePinho RA, Teti A, Ducy P, Karsenty G.

Cell. 2010 Jul 23;142(2):296-308. doi: 10.1016/j.cell.2010.06.003.


An ELISA-based method to quantify osteocalcin carboxylation in mice.

Ferron M, Wei J, Yoshizawa T, Ducy P, Karsenty G.

Biochem Biophys Res Commun. 2010 Jul 9;397(4):691-6. doi: 10.1016/j.bbrc.2010.06.008. Epub 2010 Jun 4.


Co-dependence of bone and energy metabolisms.

Wei J, Ducy P.

Arch Biochem Biophys. 2010 Nov 1;503(1):35-40. doi: 10.1016/ Epub 2010 May 31. Review.


Lrp5 and bone formation : A serotonin-dependent pathway.

Yadav VK, Ducy P.

Ann N Y Acad Sci. 2010 Mar;1192:103-9. doi: 10.1111/j.1749-6632.2009.05312.x. Review.


Genetic analysis of Lrp5 function in osteoblast progenitors.

Yadav VK, Arantes HP, Barros ER, Lazaretti-Castro M, Ducy P.

Calcif Tissue Int. 2010 May;86(5):382-8. doi: 10.1007/s00223-010-9350-7. Epub 2010 Mar 24.


Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis.

Yadav VK, Balaji S, Suresh PS, Liu XS, Lu X, Li Z, Guo XE, Mann JJ, Balapure AK, Gershon MD, Medhamurthy R, Vidal M, Karsenty G, Ducy P.

Nat Med. 2010 Mar;16(3):308-12. doi: 10.1038/nm.2098. Epub 2010 Feb 7.


Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum.

Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, Mann JJ, Hen R, Ducy P, Karsenty G.

Cell. 2008 Nov 28;135(5):825-37. doi: 10.1016/j.cell.2008.09.059.


Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production.

Dakhova O, O'Day D, Kinet N, Yucer N, Wiese M, Shetty G, Ducy P.

Endocrinology. 2009 Jan;150(1):404-12. doi: 10.1210/en.2008-0673. Epub 2008 Sep 25.


Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice.

Ferron M, Hinoi E, Karsenty G, Ducy P.

Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5266-70. doi: 10.1073/pnas.0711119105. Epub 2008 Mar 24.


Endocrine regulation of energy metabolism by the skeleton.

Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G.

Cell. 2007 Aug 10;130(3):456-69.

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