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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 2
1980 1
1981 1
1982 2
1985 2
1987 1
1988 2
1990 1
2008 1
2009 1
2016 1
2017 1
2023 1
2024 0

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15 results

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Page 1
Renal effects of pinane-thromboxane A2 and indomethacin in saline volume-expanded spontaneously hypertensive rats.
Shibouta Y, Terashita ZI, Inada Y, Kato K, Nishikawa K. Shibouta Y, et al. Eur J Pharmacol. 1982 Nov 5;85(1):51-9. doi: 10.1016/0014-2999(82)90423-x. Eur J Pharmacol. 1982. PMID: 7151863
In 6-week old spontaneously hypertensive rats (SHR), indomethacin (5 mg/kg i.v.) and pinane-thromboxane A2 (PTA2) (50 micrograms/kg per h i.v.) a thromboxane A2 (TXA2) antagonist as well as a TXA2 synthetase inhibitor, resulted in natriuresis accompani …
In 6-week old spontaneously hypertensive rats (SHR), indomethacin (5 mg/kg i.v.) and pinane-thromboxane A2 (PTA2 …
Preservation of ischemic myocardium by pinane thromboxane A2.
Schrör K, Smith EF 3rd, Bickerton M, Smith JB, Nicolaou KC, Magolda R, Lefer AM. Schrör K, et al. Am J Physiol. 1980 Jan;238(1):H87-92. doi: 10.1152/ajpheart.1980.238.1.H87. Am J Physiol. 1980. PMID: 7356037
Pinane thromboxane A2 (PTA2), a thromboxane A2 analog has been shown to antagonize the vasoconstriction and platelet aggregation induced by thromboxane A2, in addition to specifically inhibiting thromboxane synthetase. ...Moreover, ECG analysis reveale …
Pinane thromboxane A2 (PTA2), a thromboxane A2 analog has been shown to antagonize the vasoconstriction and plat …
Identification of fecal microbiome signatures associated with familial longevity and candidate metabolites for healthy aging.
Gong J, Liu S, Wang S, Ruan H, Mou Q, Fan P, Chen T, Cai W, Lu Y, Lu Z. Gong J, et al. Aging Cell. 2023 Jun;22(6):e13848. doi: 10.1111/acel.13848. Epub 2023 May 2. Aging Cell. 2023. PMID: 37132117 Free PMC article.
Specifically, we identified that the levels of a candidate metabolite, pinane thromboxane A2 (PTA2), which is positively associated with aging, were consistently higher in individuals with familial longevity and their younger descendants than in those …
Specifically, we identified that the levels of a candidate metabolite, pinane thromboxane A2 (PTA2), which is po …
Synthesis and biological properties of pinane-thromboxane A2, a selective inhibitor of coronary artery constriction, platelet aggregation, and thromboxane formation.
Nicolaou KC, Magolda RL, Smith JB, Aharony D, Smith EF, Lefer AM. Nicolaou KC, et al. Proc Natl Acad Sci U S A. 1979 Jun;76(6):2566-70. doi: 10.1073/pnas.76.6.2566. Proc Natl Acad Sci U S A. 1979. PMID: 288046 Free PMC article.
Pinane-thromboxane A2 (PTA2, [1alpha,2 beta(Z),-3 alpha (1E,3R*),5 alpha]-7-(3-(3-hydroxy-1-octenyl)-6,6-dimethylbicyclo[3.1.1]hept-2-yl)-5-heptenoic acid) has been synthesized and tested for biological activity in systems responsive to thromboxane A2, …
Pinane-thromboxane A2 (PTA2, [1alpha,2 beta(Z),-3 alpha (1E,3R*),5 alpha]-7-(3-(3-hydroxy-1-octenyl)-6,6-dimethy …
U46619 and carbocyclic thromboxane A2-induced increases in tracheal mucous gel layer thickness.
Yanni JM, Smith WL, Foxwell MH. Yanni JM, et al. Prostaglandins Leukot Essent Fatty Acids. 1988 Apr;32(1):45-9. doi: 10.1016/0952-3278(88)90093-2. Prostaglandins Leukot Essent Fatty Acids. 1988. PMID: 3387452
Significant gel thickening was observed at doses ranging from 3.5 pg to 35 ng and from 500 pg to 50 ng for U46619 and CTA2, respectively. Intravenous treatment with pinane thromboxane A2 (PTA2), a thromboxane antagonist, prior to injection of U46619 or …
Significant gel thickening was observed at doses ranging from 3.5 pg to 35 ng and from 500 pg to 50 ng for U46619 and CTA2, respectively. In …
Competitive antagonism at thromboxane receptors in human platelets.
Armstrong RA, Jones RL, Peesapati V, Will SG, Wilson NH. Armstrong RA, et al. Br J Pharmacol. 1985 Mar;84(3):595-607. doi: 10.1111/j.1476-5381.1985.tb16139.x. Br J Pharmacol. 1985. PMID: 2580580 Free PMC article.
The inhibitory effects of three prostanoid analogues, EP 045, EP 092 and pinane thromboxane A2 (PTA2), on the aggregation of human platelets in vitro have been investigated. ...PTA2, therefore, has a thromboxane-like agonist action. The block of …
The inhibitory effects of three prostanoid analogues, EP 045, EP 092 and pinane thromboxane A2 (PTA2), on the ag …
Thromboxane synthetase inhibitors differentially antagonize thromboxane receptors in vascular smooth muscle.
Smith EF 3rd, Lefer AM, Smith JB, Nicolaou KC. Smith EF 3rd, et al. Naunyn Schmiedebergs Arch Pharmacol. 1981 Dec;318(2):130-4. doi: 10.1007/BF00508837. Naunyn Schmiedebergs Arch Pharmacol. 1981. PMID: 6276789
However, little is known about Tx receptor antagonism by these substances. Imidazole, UK-37,248 and pinane thromboxane A2 (PTA2) were tested in isolated perfused cat coronary arteries, spirally cut rabbit pulmonary artery strips, and in rabbit and cat …
However, little is known about Tx receptor antagonism by these substances. Imidazole, UK-37,248 and pinane thromboxane A2 …
Structural specificity for prostaglandin effects on hepatocyte glycogenolysis.
Brass EP, Garrity MJ. Brass EP, et al. Biochem J. 1990 Apr 1;267(1):59-62. doi: 10.1042/bj2670059. Biochem J. 1990. PMID: 2158311 Free PMC article.
PGF and PGB2 inhibited glucagon-stimulated glycogenolysis in the hepatocyte system. Pinane thromboxane A2 (PTA2) and PGD2 had no effect on glucagon-stimulated glycogenolysis. ...Additionally, PGE2, PGF2 alpha and PGB2 inhibited glucagon-stimulated aden …
PGF and PGB2 inhibited glucagon-stimulated glycogenolysis in the hepatocyte system. Pinane thromboxane A2 (PTA2) …
15 results