Format

Send to

Choose Destination

See 1 citation:

J Virol. 2015 Feb;89(3):1489-501. doi: 10.1128/JVI.02027-14. Epub 2014 Nov 26.

Unraveling the web of viroinformatics: computational tools and databases in virus research.

Author information

1
Vaccine and Infectious Disease Research Centre, Translational Health Science and Technology Institute, Gurgaon, India deepak@thsti.res.in.
2
Vaccine and Infectious Disease Research Centre, Translational Health Science and Technology Institute, Gurgaon, India.

Abstract

The beginning of the second century of research in the field of virology (the first virus was discovered in 1898) was marked by its amalgamation with bioinformatics, resulting in the birth of a new domain--viroinformatics. The availability of more than 100 Web servers and databases embracing all or specific viruses (for example, dengue virus, influenza virus, hepatitis virus, human immunodeficiency virus [HIV], hemorrhagic fever virus [HFV], human papillomavirus [HPV], West Nile virus, etc.) as well as distinct applications (comparative/diversity analysis, viral recombination, small interfering RNA [siRNA]/short hairpin RNA [shRNA]/microRNA [miRNA] studies, RNA folding, protein-protein interaction, structural analysis, and phylotyping and genotyping) will definitely aid the development of effective drugs and vaccines. However, information about their access and utility is not available at any single source or on any single platform. Therefore, a compendium of various computational tools and resources dedicated specifically to virology is presented in this article.

PMID:
25428870
PMCID:
PMC4300767
DOI:
10.1128/JVI.02027-14
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center