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J Invest Dermatol. 2018 Mar;138(3):480-482. doi: 10.1016/j.jid.2017.10.019.

Adipose and Hair Function: An aPPARent Connection.

Author information

1
Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
2
Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: LAG@jhmi.edu.

Abstract

Adipose tissue plays essential roles in various aspects of skin physiology, from regulating hair follicle morphogenesis to wound healing. Peroxisome proliferator-activated receptor gamma is important for the maintenance of adipose tissue and has been implicated in some types of hair loss; however, its function during the hair cycle is still unclear. Sardella et al. investigate the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel global peroxisome proliferator-activated receptor gamma-null mouse.

PMID:
29477189
PMCID:
PMC6399744
DOI:
10.1016/j.jid.2017.10.019
[Indexed for MEDLINE]
Free PMC Article

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