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Items: 1 to 20 of 86


Very rapid flow cytometric assessment of antimicrobial susceptibility during the apparent lag phase of microbial (re)growth.

Jindal S, Thampy H, Day PJR, Kell DB.

Microbiology. 2019 Feb 11. doi: 10.1099/mic.0.000777. [Epub ahead of print]


Peripheral blood RNA gene expression in children with pneumococcal meningitis: a prospective case-control study.

Kulohoma BW, Marriage F, Vasieva O, Mankhambo L, Nguyen K, Molyneux ME, Molyneux EM, Day PJR, Carrol ED.

BMJ Paediatr Open. 2017 Aug 31;1(1):e000092. doi: 10.1136/bmjpo-2017-000092. eCollection 2017.


GeneGini: Assessment via the Gini Coefficient of Reference "Housekeeping" Genes and Diverse Human Transporter Expression Profiles.

O'Hagan S, Wright Muelas M, Day PJ, Lundberg E, Kell DB.

Cell Syst. 2018 Feb 28;6(2):230-244.e1. doi: 10.1016/j.cels.2018.01.003. Epub 2018 Feb 7.


Integrative analysis of rewired central metabolism in temozolomide resistant cells.

Immanuel SRC, Ghanate AD, Parmar DS, Marriage F, Panchagnula V, Day PJ, Raghunathan A.

Biochem Biophys Res Commun. 2018 Jan 8;495(2):2010-2016. doi: 10.1016/j.bbrc.2017.12.073. Epub 2017 Dec 14.


Endoplasmic reticulum chaperone prolyl 4-hydroxylase, beta polypeptide (P4HB) promotes malignant phenotypes in glioma via MAPK signaling.

Sun S, Kiang KMY, Ho ASW, Lee D, Poon MW, Xu FF, Pu JKS, Kan ANC, Lee NPY, Liu XB, Man K, Day PJR, Lui WM, Fung CF, Leung GKK.

Oncotarget. 2017 May 19;8(42):71911-71923. doi: 10.18632/oncotarget.18026. eCollection 2017 Sep 22.


Computing exponentially faster: implementing a non-deterministic universal Turing machine using DNA.

Currin A, Korovin K, Ababi M, Roper K, Kell DB, Day PJ, King RD.

J R Soc Interface. 2017 Mar;14(128). pii: 20160990. doi: 10.1098/rsif.2016.0990.


Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2).

Woolford AJ, Day PJ, Bénéton V, Berdini V, Coyle JE, Dudit Y, Grondin P, Huet P, Lee LY, Manas ES, McMenamin RL, Murray CW, Page LW, Patel VK, Potvain F, Rich SJ, Sang Y, Somers DO, Trottet L, Wan Z, Zhang X.

J Med Chem. 2016 Dec 8;59(23):10738-10749. Epub 2016 Nov 18.


SpeedyGenes: Exploiting an Improved Gene Synthesis Method for the Efficient Production of Synthetic Protein Libraries for Directed Evolution.

Currin A, Swainston N, Day PJ, Kell DB.

Methods Mol Biol. 2017;1472:63-78. doi: 10.1007/978-1-4939-6343-0_5.


Systematic protein-protein interaction and pathway analyses in the idiopathic inflammatory myopathies.

Parkes JE, Rothwell S, Day PJ, McHugh NJ, Betteridge ZE, Cooper RG, Ollier WE, Chinoy H, Lamb JA; Myositis Genetics Consortium (MYOGEN).

Arthritis Res Ther. 2016 Jul 7;18(1):156. doi: 10.1186/s13075-016-1061-7.


Integrated Electrowetting Nanoinjector for Single Cell Transfection.

Shekaramiz E, Varadarajalu G, Day PJ, Wickramasinghe HK.

Sci Rep. 2016 Jul 4;6:29051. doi: 10.1038/srep29051.


Transcriptome analysis of human ageing in male skin shows mid-life period of variability and central role of NF-κB.

Haustead DJ, Stevenson A, Saxena V, Marriage F, Firth M, Silla R, Martin L, Adcroft KF, Rea S, Day PJ, Melton P, Wood FM, Fear MW.

Sci Rep. 2016 May 27;6:26846. doi: 10.1038/srep26846.


Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening.

Woolford AJ, Pero JE, Aravapalli S, Berdini V, Coyle JE, Day PJ, Dodson AM, Grondin P, Holding FP, Lee LY, Li P, Manas ES, Marino J Jr, Martin AC, McCleland BW, McMenamin RL, Murray CW, Neipp CE, Page LW, Patel VK, Potvain F, Rich S, Rivero RA, Smith K, Somers DO, Trottet L, Velagaleti R, Williams G, Xie R.

J Med Chem. 2016 Jun 9;59(11):5356-67. doi: 10.1021/acs.jmedchem.6b00212. Epub 2016 May 20.


The role of microRNAs in the idiopathic inflammatory myopathies.

Parkes JE, Day PJ, Chinoy H, Lamb JA.

Curr Opin Rheumatol. 2015 Nov;27(6):608-15. doi: 10.1097/BOR.0000000000000225. Review.


Systems Medicine: The Application of Systems Biology Approaches for Modern Medical Research and Drug Development.

Ayers D, Day PJ.

Mol Biol Int. 2015;2015:698169. doi: 10.1155/2015/698169. Epub 2015 Aug 18. Review.


Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP.

Chessari G, Buck IM, Day JE, Day PJ, Iqbal A, Johnson CN, Lewis EJ, Martins V, Miller D, Reader M, Rees DC, Rich SJ, Tamanini E, Vitorino M, Ward GA, Williams PA, Williams G, Wilsher NE, Woolford AJ.

J Med Chem. 2015 Aug 27;58(16):6574-88. doi: 10.1021/acs.jmedchem.5b00706. Epub 2015 Aug 7.


Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.

Currin A, Swainston N, Day PJ, Kell DB.

Chem Soc Rev. 2015 Mar 7;44(5):1172-239. doi: 10.1039/c4cs00351a. Review.


SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution.

Currin A, Swainston N, Day PJ, Kell DB.

Protein Eng Des Sel. 2014 Sep;27(9):273-80. doi: 10.1093/protein/gzu029. Epub 2014 Aug 9.


Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO.

Cleasby A, Yon J, Day PJ, Richardson C, Tickle IJ, Williams PA, Callahan JF, Carr R, Concha N, Kerns JK, Qi H, Sweitzer T, Ward P, Davies TG.

PLoS One. 2014 Jun 4;9(6):e98896. doi: 10.1371/journal.pone.0098896. eCollection 2014.


GeneGenie: optimized oligomer design for directed evolution.

Swainston N, Currin A, Day PJ, Kell DB.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W395-400. doi: 10.1093/nar/gku336. Epub 2014 Apr 29.

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