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Items: 1 to 20 of 120

1.

Pharmacokinetics and efficacy of orally administered polymeric chloroquine as macromolecular drug in the treatment of inflammatory bowel disease.

Kanvinde S, Chhonker YS, Ahmad R, Yu F, Sleightholm R, Tang W, Jaramillo L, Chen Y, Sheinin Y, Li J, Murry DJ, Singh AB, Oupický D.

Acta Biomater. 2018 Dec;82:158-170. doi: 10.1016/j.actbio.2018.10.027. Epub 2018 Oct 17.

PMID:
30342282
2.

ATP-activated decrosslinking and charge-reversal vectors for siRNA delivery and cancer therapy.

Zhou Z, Zhang Q, Zhang M, Li H, Chen G, Qian C, Oupicky D, Sun M.

Theranostics. 2018 Sep 9;8(17):4604-4619. doi: 10.7150/thno.26889. eCollection 2018.

3.

Cholesterol Modification Enhances Antimetastatic Activity and siRNA Delivery Efficacy of Poly(ethylenimine)-Based CXCR4 Antagonists.

Wu P, Luo X, Wu H, Yu F, Wang K, Sun M, Oupicky D.

Macromol Biosci. 2018 Nov;18(11):e1800234. doi: 10.1002/mabi.201800234. Epub 2018 Sep 27.

PMID:
30259651
4.

Cholangiocarcinoma therapy with nanoparticles that combine downregulation of MicroRNA-210 with inhibition of cancer cell invasiveness.

Xie Y, Wang Y, Li J, Hang Y, Jaramillo L, Wehrkamp CJ, Phillippi MA, Mohr AM, Chen Y, Talmon GA, Mott JL, Oupický D.

Theranostics. 2018 Jul 30;8(16):4305-4320. doi: 10.7150/thno.26506. eCollection 2018.

5.

Charge and Assembly Reversible Micelles Fueled by Intracellular ATP for Improved siRNA Transfection.

Zhou Z, Li C, Zhang M, Zhang Q, Qian C, Oupicky D, Sun M.

ACS Appl Mater Interfaces. 2018 Sep 26;10(38):32026-32037. doi: 10.1021/acsami.8b13300. Epub 2018 Sep 17.

PMID:
30179452
6.

Reversible Covalent Cross-Linked Polycations with Enhanced Stability and ATP-Responsive Behavior for Improved siRNA Delivery.

Zhou Z, Zhang M, Liu Y, Li C, Zhang Q, Oupicky D, Sun M.

Biomacromolecules. 2018 Sep 10;19(9):3776-3787. doi: 10.1021/acs.biomac.8b00922. Epub 2018 Aug 15.

PMID:
30081638
7.

Polymeric Prodrugs Targeting Polyamine Metabolism Inhibit Zika Virus Replication.

Routhu NK, Xie Y, Dunworth M, Casero RA Jr, Oupicky D, Byrareddy SN.

Mol Pharm. 2018 Sep 4;15(9):4284-4295. doi: 10.1021/acs.molpharmaceut.8b00068. Epub 2018 Aug 6.

PMID:
30040423
8.

Reversibly Stabilized Polycation Nanoparticles for Combination Treatment of Early- and Late-Stage Metastatic Breast Cancer.

Chen G, Wang Y, Wu P, Zhou Y, Yu F, Zhu C, Li Z, Hang Y, Wang K, Li J, Sun M, Oupicky D.

ACS Nano. 2018 Jul 24;12(7):6620-6636. doi: 10.1021/acsnano.8b01482. Epub 2018 Jul 9.

PMID:
29985577
9.

Near-infrared light-activated IR780-loaded liposomes for anti-tumor angiogenesis and Photothermal therapy.

Yang X, Li H, Qian C, Guo Y, Li C, Gao F, Yang Y, Wang K, Oupicky D, Sun M.

Nanomedicine. 2018 Oct;14(7):2283-2294. doi: 10.1016/j.nano.2018.06.011. Epub 2018 Jul 4.

PMID:
29981460
10.

Pulmonary delivery of polyplexes for combined PAI-1 gene silencing and CXCR4 inhibition to treat lung fibrosis.

Ding L, Zhu C, Yu F, Wu P, Chen G, Ullah A, Wang K, Sun M, Li J, Oupický D.

Nanomedicine. 2018 Aug;14(6):1765-1776. doi: 10.1016/j.nano.2018.05.005. Epub 2018 May 16.

PMID:
29777878
11.

Promise of chemokine network-targeted nanoparticles in combination nucleic acid therapies of metastatic cancer.

Xie Y, Wang Y, Li J, Hang Y, Oupický D.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 Apr 26:e1528. doi: 10.1002/wnan.1528. [Epub ahead of print] Review.

PMID:
29700990
12.

Bioreduction-ruptured nanogel for switch on/off release of Bcl2 siRNA in breast tumor therapy.

Li H, Yang X, Gao F, Qian C, Li C, Oupicky D, Sun M.

J Control Release. 2018 Feb 27;292:78-90. doi: 10.1016/j.jconrel.2018.02.036. [Epub ahead of print]

PMID:
29499219
13.

Histone Deacetylase Inhibitor (HDACi) Conjugated Polycaprolactone for Combination Cancer Therapy.

Kularatne RN, Washington KE, Bulumulla C, Calubaquib EL, Biewer MC, Oupicky D, Stefan MC.

Biomacromolecules. 2018 Mar 12;19(3):1082-1089. doi: 10.1021/acs.biomac.8b00221. Epub 2018 Feb 27.

14.

Cyclam-Modified PEI for Combined VEGF siRNA Silencing and CXCR4 Inhibition To Treat Metastatic Breast Cancer.

Zhou Y, Yu F, Zhang F, Chen G, Wang K, Sun M, Li J, Oupický D.

Biomacromolecules. 2018 Feb 12;19(2):392-401. doi: 10.1021/acs.biomac.7b01487. Epub 2018 Jan 19.

PMID:
29350899
15.

Conjugate Polyplexes with Anti-Invasive Properties and Improved siRNA Delivery In Vivo.

Chen Y, Li J, Oupický D.

Bioconjug Chem. 2018 Feb 21;29(2):296-305. doi: 10.1021/acs.bioconjchem.7b00622. Epub 2018 Jan 17.

16.

Fluorination Enhances Serum Stability of Bioreducible Poly(amido amine) Polyplexes and Enables Efficient Intravenous siRNA Delivery.

Chen G, Wang K, Wang Y, Wu P, Sun M, Oupický D.

Adv Healthc Mater. 2018 Mar;7(5). doi: 10.1002/adhm.201700978. Epub 2017 Dec 27.

PMID:
29280311
17.

Advances in Stimulus-Responsive Polymeric Materials for Systemic Delivery of Nucleic Acids.

Sun M, Wang K, Oupický D.

Adv Healthc Mater. 2018 Feb;7(4). doi: 10.1002/adhm.201701070. Epub 2017 Dec 11. Review.

PMID:
29227047
18.

Simultaneous quantitation of hydroxychloroquine and its metabolites in mouse blood and tissues using LC-ESI-MS/MS: An application for pharmacokinetic studies.

Chhonker YS, Sleightholm RL, Li J, Oupický D, Murry DJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jan 1;1072:320-327. doi: 10.1016/j.jchromb.2017.11.026. Epub 2017 Nov 23.

PMID:
29207305
19.

Coordination-driven assembly of catechol-modified chitosan for the kidney-specific delivery of salvianolic acid B to treat renal fibrosis.

Li J, Zhang C, He W, Qiao H, Chen J, Wang K, Oupický D, Sun M.

Biomater Sci. 2017 Dec 19;6(1):179-188. doi: 10.1039/c7bm00811b.

PMID:
29170782
20.

Synthesis and Evaluation of Chloroquine-Containing DMAEMA Copolymers as Efficient Anti-miRNA Delivery Vectors with Improved Endosomal Escape and Antimigratory Activity in Cancer Cells.

Xie Y, Yu F, Tang W, Alade BO, Peng ZH, Wang Y, Li J, Oupický D.

Macromol Biosci. 2018 Jan;18(1). doi: 10.1002/mabi.201700194. Epub 2017 Aug 4.

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