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Items: 1 to 20 of 103

1.

Structural attributes influencing unbound tissue distribution.

Orozco CC, Atkinson K, Ryu S, Chang G, Keefer C, Lin J, Riccardi K, Mongillo RK, Tess D, Filipski KJ, Kalgutkar AS, Litchfield J, Scott D, Di L.

Eur J Med Chem. 2020 Jan 1;185:111813. doi: 10.1016/j.ejmech.2019.111813. Epub 2019 Oct 28.

PMID:
31732255
2.

Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization.

Davoren JE, Nason D, Coe J, Dlugolenski K, Helal C, Harris AR, LaChapelle E, Liang S, Liu Y, O'Connor R, Orozco CC, Rai BK, Salafia M, Samas B, Xu W, Kozak R, Gray D.

J Med Chem. 2018 Dec 27;61(24):11384-11397. doi: 10.1021/acs.jmedchem.8b01622. Epub 2018 Dec 11.

PMID:
30431269
3.

Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker.

Martinez-Bosch N, Barranco LE, Orozco CA, Moreno M, Visa L, Iglesias M, Oldfield L, Neoptolemos JP, Greenhalf W, Earl J, Carrato A, Costello E, Navarro P.

Oncotarget. 2018 Aug 31;9(68):32984-32996. doi: 10.18632/oncotarget.26034. eCollection 2018 Aug 31.

4.

6-Chloro-5-[4-(1-Hydroxycyclobutyl)Phenyl]-1H-Indole-3-Carboxylic Acid is a Highly Selective Substrate for Glucuronidation by UGT1A1, Relative to β-Estradiol.

Lapham K, Lin J, Novak J, Orozco C, Niosi M, Di L, Goosen TC, Ryu S, Riccardi K, Eng H, Cameron KO, Kalgutkar AS.

Drug Metab Dispos. 2018 Dec;46(12):1836-1846. doi: 10.1124/dmd.118.083709. Epub 2018 Sep 7.

PMID:
30194276
5.

Discovery of Potent and Selective Periphery-Restricted Quinazoline Inhibitors of the Cyclic Nucleotide Phosphodiesterase PDE1.

Humphrey JM, Movsesian M, Am Ende CW, Becker SL, Chappie TA, Jenkinson S, Liras JL, Liras S, Orozco C, Pandit J, Vajdos FF, Vandeput F, Yang E, Menniti FS.

J Med Chem. 2018 May 24;61(10):4635-4640. doi: 10.1021/acs.jmedchem.8b00374. Epub 2018 May 10.

PMID:
29718668
6.

Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.

Orozco CA, Martinez-Bosch N, Guerrero PE, Vinaixa J, Dalotto-Moreno T, Iglesias M, Moreno M, Djurec M, Poirier F, Gabius HJ, Fernandez-Zapico ME, Hwang RF, Guerra C, Rabinovich GA, Navarro P.

Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3769-E3778. doi: 10.1073/pnas.1722434115. Epub 2018 Apr 3.

7.

Interfacial Connection Mechanisms in Calcium-Silicate-Hydrates/Polymer Nanocomposites: A Molecular Dynamics Study.

Zhou Y, Hou D, Manzano H, Orozco CA, Geng G, Monteiro PJM, Liu J.

ACS Appl Mater Interfaces. 2017 Nov 22;9(46):41014-41025. doi: 10.1021/acsami.7b12795. Epub 2017 Nov 7.

PMID:
29076343
8.

Characterization of the Bonds Developed between Calcium Silicate Hydrate and Polycarboxylate-Based Superplasticizers with Silyl Functionalities.

Orozco CA, Chun BW, Geng G, Emwas AH, Monteiro PJ.

Langmuir. 2017 Apr 11;33(14):3404-3412. doi: 10.1021/acs.langmuir.6b04368. Epub 2017 Mar 30.

PMID:
28328229
9.

Rheumatology Informatics System for Effectiveness: A National Informatics-Enabled Registry for Quality Improvement.

Yazdany J, Bansback N, Clowse M, Collier D, Law K, Liao KP, Michaud K, Morgan EM, Oates JC, Orozco C, Reimold A, Simard JF, Myslinski R, Kazi S.

Arthritis Care Res (Hoboken). 2016 Dec;68(12):1866-1873. doi: 10.1002/acr.23089.

10.

Methods for Developing the American College of Rheumatology's Electronic Clinical Quality Measures.

Yazdany J, Myslinski R, Miller A, Francisco M, Desai S, Schmajuk G, Lacaille D, Barber CE, Orozco C, Bunyard M, Bergman MJ, Passo M, Matteson EL, Olson R, Silverman S, Warren R, Nola K, Robbins M.

Arthritis Care Res (Hoboken). 2016 Oct;68(10):1402-9. doi: 10.1002/acr.22985. Epub 2016 Sep 16. Review. No abstract available.

11.

The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer.

Martínez-Bosch N, Guerrero PE, Moreno M, José A, Iglesias M, Munné-Collado J, Anta H, Gibert J, Orozco CA, Vinaixa J, Fillat C, Viñals F, Navarro P.

Oncotarget. 2016 Jul 26;7(30):48265-48279. doi: 10.18632/oncotarget.10199.

12.

Evaluation of learned helplessness, self-efficacy and disease activity, functional capacity and pain in Argentinian patients with rheumatoid arthritis.

Vergara F, Rosa J, Orozco C, Bertiller E, Gallardo MA, Bravo M, Catay E, Collado V, Gómez G, Sabelli M, García MV, Rosemffet MG, Citera G, Schneeberger EE, Catoggio LJ, Soriano ER.

Scand J Rheumatol. 2017 Jan;46(1):17-21. doi: 10.3109/03009742.2016.1155643. Epub 2016 Apr 20.

PMID:
27095187
13.

Objective Sleep Assessments in Patients with Postural Tachycardia Syndrome using Overnight Polysomnograms.

Bagai K, Peltier AC, Malow BA, Diedrich A, Shibao CA, Black BK, Paranjape SY, Orozco C, Biaggioni I, Robertson D, Raj SR.

J Clin Sleep Med. 2016 May 15;12(5):727-33. doi: 10.5664/jcsm.5806.

14.

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

Lutz SM, Cho MH, Young K, Hersh CP, Castaldi PJ, McDonald ML, Regan E, Mattheisen M, DeMeo DL, Parker M, Foreman M, Make BJ, Jensen RL, Casaburi R, Lomas DA, Bhatt SP, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Laird NM, Lange C, Hokanson JE, Silverman EK; ECLIPSE Investigators; COPDGene Investigators.

BMC Genet. 2015 Dec 3;16:138. doi: 10.1186/s12863-015-0299-4.

15.

Chromatographic resolution of atropisomers for toxicity and biotransformation studies in pharmaceutical research.

Yan TQ, Riley F, Philippe L, Davoren J, Cox L, Orozco C, Rai B, Hardink M.

J Chromatogr A. 2015 Jun 12;1398:108-20. doi: 10.1016/j.chroma.2015.04.023. Epub 2015 Apr 23.

PMID:
25937130
16.

Comparison between an alternative and the classic definition of chronic bronchitis in COPDGene.

Kim V, Crapo J, Zhao H, Jones PW, Silverman EK, Comellas A, Make BJ, Criner GJ; COPDGene Investigators.

Ann Am Thorac Soc. 2015 Mar;12(3):332-9. doi: 10.1513/AnnalsATS.201411-518OC.

17.

Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations.

Casero CN, Oberti JC, Orozco CI, Cárdenas A, Brito I, Barboza GE, Nicotra VE.

Phytochemistry. 2015 Feb;110:83-90. doi: 10.1016/j.phytochem.2014.11.015. Epub 2014 Nov 27.

PMID:
25435174
18.

Positive C4d in kidney transplantation biopsy: clinical impact.

Pedraza N, Girón F, Baez Y, Niño A, Rodriguez J, Orozco C.

Transplant Proc. 2014 Nov;46(9):2966-71. doi: 10.1016/j.transproceed.2014.06.056.

PMID:
25420802
19.

Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus.

Hersh CP, Make BJ, Lynch DA, Barr RG, Bowler RP, Calverley PM, Castaldi PJ, Cho MH, Coxson HO, DeMeo DL, Foreman MG, Han MK, Harshfield BJ, Hokanson JE, Lutz S, Ramsdell JW, Regan EA, Rennard SI, Schroeder JD, Sciurba FC, Steiner RM, Tal-Singer R, van Beek E Jr, Silverman EK, Crapo JD; COPDGene and ECLIPSE Investigators.

BMC Pulm Med. 2014 Oct 24;14:164. doi: 10.1186/1471-2466-14-164.

20.

Pneumothorax risk factors in smokers with and without chronic obstructive pulmonary disease.

Hobbs BD, Foreman MG, Bowler R, Jacobson F, Make BJ, Castaldi PJ, San José Estépar R, Silverman EK, Hersh CP; COPDGene Investigators.

Ann Am Thorac Soc. 2014 Nov;11(9):1387-94. doi: 10.1513/AnnalsATS.201405-224OC.

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