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ACS Chem Neurosci. 2015 Jul 15;6(7):944-7. doi: 10.1021/acschemneuro.5b00081. Epub 2015 Mar 20.

Optogenetic and Chemogenetic Approaches To Advance Monitoring Molecules.

Author information

1
Bowles Center for Alcohol Studies and Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27759, United States.

Abstract

Fast-scan cyclic voltammetry (FSCV) is a high-resolution technique used to investigate neurotransmission in vitro, ex vivo, and in vivo. In this Viewpoint, I discuss how optogenetic and chemogenetic methods, when combined with FSCV, can impact and advance our understanding of neurotransmission and enable more detailed investigation of the roles of neurotransmitter systems in normal and disease states.

KEYWORDS:

Fast-scan cyclic voltammetry; chemogenetics; dopamine; norepinephrine; optogenetics; serotonin

PMID:
25791746
DOI:
10.1021/acschemneuro.5b00081
[Indexed for MEDLINE]

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