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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1905 3
1906 4
1907 21
1908 8
1909 6
1910 2
1911 3
1912 4
1914 3
1915 1
1916 2
1917 1
1919 2
1920 2
1927 1
1928 1
1933 1
1934 1
1935 1
1939 1
1946 2
1947 3
1948 1
1950 3
1951 3
1952 3
1953 2
1954 5
1955 3
1956 4
1957 2
1958 2
1959 4
1960 8
1961 2
1962 3
1963 7
1964 11
1965 8
1966 14
1967 11
1968 9
1969 21
1970 16
1971 19
1972 18
1973 27
1974 25
1975 64
1976 63
1977 99
1978 108
1979 133
1980 142
1981 183
1982 189
1983 223
1984 293
1985 292
1986 259
1987 278
1988 316
1989 352
1990 323
1991 300
1992 293
1993 283
1994 283
1995 247
1996 247
1997 235
1998 214
1999 220
2000 204
2001 221
2002 191
2003 196
2004 212
2005 209
2006 222
2007 208
2008 195
2009 211
2010 211
2011 223
2012 224
2013 186
2014 213
2015 222
2016 236
2017 239
2018 203
2019 203
2020 229
2021 242
2022 224
2023 169
2024 64

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10,614 results

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Page 1
Evasion of opsonization of macromolecules using novel surface-modification and biological-camouflage-mediated techniques for next-generation drug delivery.
Mehta P, Shende P. Mehta P, et al. Cell Biochem Funct. 2023 Dec;41(8):1031-1043. doi: 10.1002/cbf.3880. Epub 2023 Nov 6. Cell Biochem Funct. 2023. PMID: 37933222 Review.
Opsonization plays a pivotal role in hindering controlled drug release from nanoformulations due to macrophage-mediated nanoparticle destruction. ...Future integration of artificial intelligence-based algorithms, integrated with nanoparticle properties such as shape, size, …
Opsonization plays a pivotal role in hindering controlled drug release from nanoformulations due to macrophage-mediated nanoparticle …
Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization.
Izadi A, Hailu A, Godzwon M, Wrighton S, Olofsson B, Schmidt T, Söderlund-Strand A, Elder E, Appelberg S, Valsjö M, Larsson O, Wendel-Hansen V, Ohlin M, Bahnan W, Nordenfelt P. Izadi A, et al. Proc Natl Acad Sci U S A. 2023 Apr 11;120(15):e2217590120. doi: 10.1073/pnas.2217590120. Epub 2023 Apr 3. Proc Natl Acad Sci U S A. 2023. PMID: 37011197 Free PMC article.
Moreover, combining mAbs into oligoclonal cocktails led to enhanced Fc- and complement receptor-mediated phagocytosis, superior to even the most potent single IgG3 mAb when compared at equivalent concentrations. Finally, in an in vivo model, we show that opsonic mAbs of bo …
Moreover, combining mAbs into oligoclonal cocktails led to enhanced Fc- and complement receptor-mediated phagocytosis, superior to even the …
Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila.
Touré H, Durand N, Guénal I, Herrmann JL, Girard-Misguich F, Szuplewski S. Touré H, et al. Microbiol Spectr. 2023 Aug 17;11(4):e0077723. doi: 10.1128/spectrum.00777-23. Epub 2023 Jun 1. Microbiol Spectr. 2023. PMID: 37260399 Free PMC article.
Furthermore, Defensin alone was sufficient to kill extracellular M. abscessus both in vitro and in vivo and control its infection. Collectively, our data support that Tep4-mediated opsonization of M. abscessus allows its escape and resistance toward the Defensin bactericid …
Furthermore, Defensin alone was sufficient to kill extracellular M. abscessus both in vitro and in vivo and control its infection. Collectiv …
Deficient Complement Opsonization Impairs Mycobacterium avium Killing by Neutrophils in Cystic Fibrosis.
Lenhart-Pendergrass PM, Malcolm KC, Wheeler E, Rysavy NM, Poch K, Caceres S, Calhoun KM, Martiniano SL, Nick JA. Lenhart-Pendergrass PM, et al. Microbiol Spectr. 2023 Feb 14;11(1):e0327922. doi: 10.1128/spectrum.03279-22. Epub 2023 Jan 18. Microbiol Spectr. 2023. PMID: 36651756 Free PMC article.
HD neutrophils had killing activity against M. avium opsonized with intact HD plasma and killing was significantly reduced when M. avium was opsonized with heat-inactivated HD plasma. ...Killing efficiency is significantly lower when the bacteria are opsonized …
HD neutrophils had killing activity against M. avium opsonized with intact HD plasma and killing was significantly reduced when M. av …
Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2.
Bahnan W, Wrighton S, Sundwall M, Bläckberg A, Larsson O, Höglund U, Khakzad H, Godzwon M, Walle M, Elder E, Strand AS, Happonen L, André O, Ahnlide JK, Hellmark T, Wendel-Hansen V, Wallin RP, Malmstöm J, Malmström L, Ohlin M, Rasmussen M, Nordenfelt P. Bahnan W, et al. Front Immunol. 2022 Jan 14;12:808932. doi: 10.3389/fimmu.2021.808932. eCollection 2021. Front Immunol. 2022. PMID: 35095897 Free PMC article.
Antibody-dependent phagocytosis is an immune mechanism enhanced by opsonization, where typically, more bound antibodies trigger a stronger phagocyte response. ...Moreover, we show that this Spike-dependent modulation of opsonization correlate with the outcome in an …
Antibody-dependent phagocytosis is an immune mechanism enhanced by opsonization, where typically, more bound antibodies trigger a str …
Opsonization but not pretreatment of equine macrophages with hyperimmune plasma nonspecifically enhances phagocytosis and intracellular killing of Rhodococcus equi.
Harvey AB, Bordin AI, Rocha JN, Bray JM, Cohen ND. Harvey AB, et al. J Vet Intern Med. 2021 Jan;35(1):590-596. doi: 10.1111/jvim.16002. Epub 2020 Dec 16. J Vet Intern Med. 2021. PMID: 33326149 Free PMC article.
In a second experiment, AMs from 6 horses were infected with R. equi either opsonized with HIP or opsonized with NP. For both experiments, AMs were lysed at 0 and 48 hours and the number of viable R. equi quantified by culture were compared among groups using linear …
In a second experiment, AMs from 6 horses were infected with R. equi either opsonized with HIP or opsonized with NP. For both …
Engineered human antibodies for the opsonization and killing of Staphylococcus aureus.
Chen X, Schneewind O, Missiakas D. Chen X, et al. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2114478119. doi: 10.1073/pnas.2114478119. Proc Natl Acad Sci U S A. 2022. PMID: 35058363 Free PMC article.
SpA captures the Fcgamma domain of IgG and interferes with opsonization by anti-S. aureus antibodies. In principle, the Fcgamma domain of therapeutic antibodies could be engineered to avoid the inhibitory activity of SpA. ...
SpA captures the Fcgamma domain of IgG and interferes with opsonization by anti-S. aureus antibodies. In principle, the Fcgamma domai …
Folic Acid Enables Targeting Delivery of Lipodiscs by Circumventing IgM-Mediated Opsonization.
Wang H, Lin S, Wang S, Jiang Z, Ding T, Wei X, Lu Y, Yang F, Zhan C. Wang H, et al. Nano Lett. 2022 Aug 24;22(16):6516-6522. doi: 10.1021/acs.nanolett.2c01509. Epub 2022 Aug 9. Nano Lett. 2022. PMID: 35943299
Herein, FA-functionalized lipodiscs (FA-Disc) were constructed to successfully circumvent IgM-mediated opsonization and retained binding activity with folate receptors in vivo. ...
Herein, FA-functionalized lipodiscs (FA-Disc) were constructed to successfully circumvent IgM-mediated opsonization and retained bind …
Unravelling Heterogeneities in Complement and Antibody Opsonization of Individual Liposomes as a Function of Surface Architecture.
Münter R, Stavnsbjerg C, Christensen E, Thomsen ME, Stensballe A, Hansen AE, Parhamifar L, Kristensen K, Simonsen JB, Larsen JB, Andresen TL. Münter R, et al. Small. 2022 Apr;18(14):e2106529. doi: 10.1002/smll.202106529. Epub 2022 Feb 20. Small. 2022. PMID: 35187804
Here, a microscopy-based method for directly quantifying opsonization at the single nanoparticle level is presented. Various surface coatings are investigated on liposomes, including PEG, and show that opsonization by both antibodies and complement C3b is highly dep …
Here, a microscopy-based method for directly quantifying opsonization at the single nanoparticle level is presented. Various surface …
Antibody Opsonization Enhances Early Interactions between Yersinia pestis and Neutrophils in the Skin and Draining Lymph Node in a Mouse Model of Bubonic Plague.
Shannon JG, Hinnebusch BJ. Shannon JG, et al. Infect Immun. 2020 Dec 15;89(1):e00061-20. doi: 10.1128/IAI.00061-20. Print 2020 Dec 15. Infect Immun. 2020. PMID: 33077628 Free PMC article.
Though polyclonal and monoclonal antibodies (Ab) can provide complete protection against bubonic plague in animal models, the mechanisms responsible for this antibody-mediated immunity (AMI) to Y. pestis remain poorly understood. Here, we examine the effects of Ab opsonization …
Though polyclonal and monoclonal antibodies (Ab) can provide complete protection against bubonic plague in animal models, the mechanisms res …
10,614 results
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