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Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates.

Yu Z, Surface LE, Park CY, Horlbeck MA, Wyant GA, Abu-Remaileh M, Peterson TR, Sabatini DM, Weissman JS, O'Shea EK.

Elife. 2018 May 10;7. pii: e36620. doi: 10.7554/eLife.36620. [Epub ahead of print]


Dynamical localization of a thylakoid membrane binding protein is required for acquisition of photosynthetic competency.

Gutu A, Chang F, O'Shea EK.

Mol Microbiol. 2018 Apr;108(1):16-31. doi: 10.1111/mmi.13912. Epub 2018 Feb 12.


ppGpp Controls Global Gene Expression in Light and in Darkness in S. elongatus.

Puszynska AM, O'Shea EK.

Cell Rep. 2017 Dec 12;21(11):3155-3165. doi: 10.1016/j.celrep.2017.11.067.


Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria.

Piechura JR, Amarnath K, O'Shea EK.

Elife. 2017 Dec 14;6. pii: e32032. doi: 10.7554/eLife.32032.


An Unstable Singularity Underlies Stochastic Phasing of the Circadian Clock in Individual Cyanobacterial Cells.

Gan S, O'Shea EK.

Mol Cell. 2017 Aug 17;67(4):659-672.e12. doi: 10.1016/j.molcel.2017.07.015. Epub 2017 Aug 10.


Inference and Evolutionary Analysis of Genome-Scale Regulatory Networks in Large Phylogenies.

Koch C, Konieczka J, Delorey T, Lyons A, Socha A, Davis K, Knaack SA, Thompson D, O'Shea EK, Regev A, Roy S.

Cell Syst. 2017 May 24;4(5):543-558.e8. doi: 10.1016/j.cels.2017.04.010.


A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae.

Choi J, Rajagopal A, Xu YF, Rabinowitz JD, O'Shea EK.

PLoS One. 2017 May 17;12(5):e0176085. doi: 10.1371/journal.pone.0176085. eCollection 2017.


Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway.

He BZ, Zhou X, O'Shea EK.

Elife. 2017 May 9;6. pii: e25157. doi: 10.7554/eLife.25157.


Cyanobacteria Maintain Constant Protein Concentration despite Genome Copy-Number Variation.

Zheng XY, O'Shea EK.

Cell Rep. 2017 Apr 18;19(3):497-504. doi: 10.1016/j.celrep.2017.03.067.


A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution.

Zhou X, Blocker AW, Airoldi EM, O'Shea EK.

Elife. 2016 Sep 13;5. pii: e16970. doi: 10.7554/eLife.16970.


The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine.

Chidley C, Trauger SA, Birsoy K, O'Shea EK.

Elife. 2016 Jul 12;5. pii: e14601. doi: 10.7554/eLife.14601.


Encoding four gene expression programs in the activation dynamics of a single transcription factor.

Hansen AS, O'Shea EK.

Curr Biol. 2016 Apr 4;26(7):R269-71. doi: 10.1016/j.cub.2016.02.058.


Correction: Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance.

Mukherji S, O'Shea EK.

Elife. 2015 Nov 24;4:e12522. doi: 10.7554/eLife.12522. No abstract available.


cis Determinants of Promoter Threshold and Activation Timescale.

Hansen AS, O'Shea EK.

Cell Rep. 2015 Aug 25;12(8):1226-33. doi: 10.1016/j.celrep.2015.07.035. Epub 2015 Aug 13.


High-throughput microfluidics to control and measure signaling dynamics in single yeast cells.

Hansen AS, Hao N, O'Shea EK.

Nat Protoc. 2015 Aug;10(8):1181-97. doi: 10.1038/nprot.2015.079. Epub 2015 Jul 9.


An integrated approach reveals regulatory controls on bacterial translation elongation.

Subramaniam AR, Zid BM, O'Shea EK.

Cell. 2014 Nov 20;159(5):1200-1211. doi: 10.1016/j.cell.2014.10.043.


Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast.

Zid BM, O'Shea EK.

Nature. 2014 Oct 2;514(7520):117-21. doi: 10.1038/nature13578. Epub 2014 Aug 3.


Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance.

Mukherji S, O'Shea EK.

Elife. 2014 Jun 10;3:e02678. doi: 10.7554/eLife.02678. Erratum in: Elife. 2015;4:e12522.

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