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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1996 3
2004 3
2005 1
2006 1
2008 1
2009 1
2011 1
2012 3
2013 2
2015 1
2018 1
2019 2
2020 2
2021 3
2022 5
2023 4
2024 1

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32 results

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Page 1
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept.
Coskun T, Urva S, Roell WC, Qu H, Loghin C, Moyers JS, O'Farrell LS, Briere DA, Sloop KW, Thomas MK, Pirro V, Wainscott DB, Willard FS, Abernathy M, Morford L, Du Y, Benson C, Gimeno RE, Haupt A, Milicevic Z. Coskun T, et al. Among authors: o farrell ls. Cell Metab. 2022 Sep 6;34(9):1234-1247.e9. doi: 10.1016/j.cmet.2022.07.013. Epub 2022 Aug 18. Cell Metab. 2022. PMID: 35985340 Free article.
GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice.
Samms RJ, Christe ME, Collins KA, Pirro V, Droz BA, Holland AK, Friedrich JL, Wojnicki S, Konkol DL, Cosgrove R, Furber EPC, Ruan X, O'Farrell LS, Long AM, Dogra M, Willency JA, Lin Y, Ding L, Cheng CC, Cabrera O, Briere DA, Alsina-Fernandez J, Gimeno RE, Moyers JS, Coskun T, Coghlan MP, Sloop KW, Roell WC. Samms RJ, et al. Among authors: o farrell ls. J Clin Invest. 2021 Jun 15;131(12):e146353. doi: 10.1172/JCI146353. J Clin Invest. 2021. PMID: 34003802 Free PMC article.
The novel dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective long-acting GLP-1 receptor agonists.
Urva S, Coskun T, Loghin C, Cui X, Beebe E, O'Farrell L, Briere DA, Benson C, Nauck MA, Haupt A. Urva S, et al. Among authors: o farrell l. Diabetes Obes Metab. 2020 Oct;22(10):1886-1891. doi: 10.1111/dom.14110. Epub 2020 Jul 13. Diabetes Obes Metab. 2020. PMID: 32519795 Free PMC article.
Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung.
Rotolo L, Vanover D, Bruno NC, Peck HE, Zurla C, Murray J, Noel RK, O'Farrell L, Araínga M, Orr-Burks N, Joo JY, Chaves LCS, Jung Y, Beyersdorf J, Gumber S, Guerrero-Ferreira R, Cornejo S, Thoresen M, Olivier AK, Kuo KM, Gumbart JC, Woolums AR, Villinger F, Lafontaine ER, Hogan RJ, Finn MG, Santangelo PJ. Rotolo L, et al. Among authors: o farrell l. Nat Mater. 2023 Mar;22(3):369-379. doi: 10.1038/s41563-022-01404-0. Epub 2022 Nov 28. Nat Mater. 2023. PMID: 36443576
Monitoring the Sialome on Human Immune Cells.
O'Farrell LK, Fraser AD, Davey GP. O'Farrell LK, et al. Methods Mol Biol. 2022;2370:323-329. doi: 10.1007/978-1-0716-1685-7_17. Methods Mol Biol. 2022. PMID: 34611878
GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice.
Furber EC, Hyatt K, Collins K, Yu X, Droz BA, Holland A, Friedrich JL, Wojnicki S, Konkol DL, O'Farrell LS, Baker HE, Coskun T, Scherer PE, Kusminski CM, Christe ME, Sloop KW, Samms RJ. Furber EC, et al. Among authors: o farrell ls. Diabetes. 2024 Feb 1;73(2):292-305. doi: 10.2337/db23-0172. Diabetes. 2024. PMID: 37934926 Free PMC article.
Glucose-dependent insulinotropic polypeptide counteracts diet-induced obesity along with reduced feeding, elevated plasma leptin and activation of leptin-responsive and proopiomelanocortin neurons in the arcuate nucleus.
Han W, Wang L, Ohbayashi K, Takeuchi M, O'Farrell L, Coskun T, Rakhat Y, Yabe D, Iwasaki Y, Seino Y, Yada T. Han W, et al. Among authors: o farrell l. Diabetes Obes Metab. 2023 Jun;25(6):1534-1546. doi: 10.1111/dom.15001. Epub 2023 Feb 28. Diabetes Obes Metab. 2023. PMID: 36852745
Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccine.
Atalis A, Keenum MC, Pandey B, Beach A, Pradhan P, Vantucci C, O'Farrell L, Noel R, Jain R, Hosten J, Smith C, Kramer L, Jimenez A, Ochoa MA, Frey D, Roy K. Atalis A, et al. Among authors: o farrell l. J Control Release. 2022 Jul;347:476-488. doi: 10.1016/j.jconrel.2022.05.023. Epub 2022 May 20. J Control Release. 2022. PMID: 35577151 Free PMC article.
32 results