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Items: 1 to 20 of 119


NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.

Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, Ganguly S, Lan T, Karin M, Kisseleva T, Brenner DA.

Gastroenterology. 2019 Mar;156(4):1156-1172.e6. doi: 10.1053/j.gastro.2018.11.019. Epub 2018 Nov 13.


Nuclear Lipid Microdomains Regulate Daunorubicin Resistance in Hepatoma Cells.

Codini M, Conte C, Cataldi S, Arcuri C, Lazzarini A, Ceccarini MR, Patria F, Floridi A, Mecca C, Ambesi-Impiombato FS, Beccari T, Curcio F, Albi E.

Int J Mol Sci. 2018 Nov 1;19(11). pii: E3424. doi: 10.3390/ijms19113424.


Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma.

Mittenbühler MJ, Sprenger HG, Gruber S, Wunderlich CM, Kern L, Brüning JC, Wunderlich FT.

Mol Metab. 2018 Nov;17:122-133. doi: 10.1016/j.molmet.2018.08.010. Epub 2018 Sep 5.


STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells.

Guha P, Gardell J, Darpolor J, Cunetta M, Lima M, Miller G, Espat NJ, Junghans RP, Katz SC.

Oncogene. 2019 Jan;38(4):533-548. doi: 10.1038/s41388-018-0449-z. Epub 2018 Aug 29.


Amentoflavone suppresses hepatocellular carcinoma by repressing hexokinase 2 expression through inhibiting JAK2/STAT3 signaling.

Liu B, Yu S.

Biomed Pharmacother. 2018 Nov;107:243-253. doi: 10.1016/j.biopha.2018.07.177. Epub 2018 Aug 8.


Increased M1 macrophages in young miR-15a/16-/- mice with tumour grafts or dextran sulphate sodium-induced colitis.

Jia X, Hu X, Han S, Miao X, Liu H, Li X, Lin Z, Wang Z, Gong W.

Scand J Immunol. 2018 Sep;88(3):e12703. doi: 10.1111/sji.12703. Epub 2018 Aug 23.


The Effects of Angelica Sinensis Polysaccharide on Tumor Growth and Iron Metabolism by Regulating Hepcidin in Tumor-Bearing Mice.

Ren F, Li J, Wang Y, Wang Y, Feng S, Yuan Z, Qian X.

Cell Physiol Biochem. 2018;47(3):1084-1094. doi: 10.1159/000490185. Epub 2018 May 25.


Ellagic Acid Holds Promise Against Hepatocellular Carcinoma in an Experimental Model: Mechanisms of Action

Zaazaa AM, Lokman MS, Shalby AB, Ahmed HH, El-Toumy SA.

Asian Pac J Cancer Prev. 2018 Feb 26;19(2):387-393.


Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway.

Li M, Yue GG, Song LH, Huang MB, Lee JK, Tsui SK, Fung KP, Tan NH, Lau CB.

Biochem Pharmacol. 2018 Apr;150:191-201. doi: 10.1016/j.bcp.2018.02.017. Epub 2018 Feb 16.


Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis.

Zhang H, Song Y, Yang H, Liu Z, Gao L, Liang X, Ma C.

Oncogene. 2018 May;37(18):2456-2468. doi: 10.1038/s41388-018-0140-4. Epub 2018 Feb 16.


The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model.

Zhan N, Michael AA, Wu K, Zeng G, Bell A, Tao J, Monga SP.

Gene Expr. 2018 May 18;18(2):135-147. doi: 10.3727/105221618X15174108894682. Epub 2018 Feb 6.


STAT3 deficiency prevents hepatocarcinogenesis and promotes biliary proliferation in thioacetamide-induced liver injury.

Abe M, Yoshida T, Akiba J, Ikezono Y, Wada F, Masuda A, Sakaue T, Tanaka T, Iwamoto H, Nakamura T, Sata M, Koga H, Yoshimura A, Torimura T.

World J Gastroenterol. 2017 Oct 7;23(37):6833-6844. doi: 10.3748/wjg.v23.i37.6833.


Targeting STAT3 to Suppress Systemic Pro-Oncogenic Effects from Hepatic Radiofrequency Ablation.

Kumar G, Goldberg SN, Gourevitch S, Levchenko T, Torchilin V, Galun E, Ahmed M.

Radiology. 2018 Feb;286(2):524-536. doi: 10.1148/radiol.2017162943. Epub 2017 Sep 6.


Morusin shows potent antitumor activity for human hepatocellular carcinoma in vitro and in vivo through apoptosis induction and angiogenesis inhibition.

Gao L, Wang L, Sun Z, Li H, Wang Q, Yi C, Wang X.

Drug Des Devel Ther. 2017 Jun 16;11:1789-1802. doi: 10.2147/DDDT.S138320. eCollection 2017.


Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice.

Jung KH, Yoo W, Stevenson HL, Deshpande D, Shen H, Gagea M, Yoo SY, Wang J, Eckols TK, Bharadwaj U, Tweardy DJ, Beretta L.

Clin Cancer Res. 2017 Sep 15;23(18):5537-5546. doi: 10.1158/1078-0432.CCR-16-2253. Epub 2017 May 22.


Nifuroxazide prompts antitumor immune response of TCL-loaded DC in mice with orthotopically-implanted hepatocarcinoma.

Zhao T, Jia H, Cheng Q, Xiao Y, Li M, Ren W, Li C, Feng Y, Feng Z, Wang H, Zheng J.

Oncol Rep. 2017 Jun;37(6):3405-3414. doi: 10.3892/or.2017.5629. Epub 2017 May 5.


Radiation improves antitumor effect of immune checkpoint inhibitor in murine hepatocellular carcinoma model.

Kim KJ, Kim JH, Lee SJ, Lee EJ, Shin EC, Seong J.

Oncotarget. 2017 Jun 20;8(25):41242-41255. doi: 10.18632/oncotarget.17168.


Antagonistic Effects of p53 and HIF1A on microRNA-34a Regulation of PPP1R11 and STAT3 and Hypoxia-induced Epithelial to Mesenchymal Transition in Colorectal Cancer Cells.

Li H, Rokavec M, Jiang L, Horst D, Hermeking H.

Gastroenterology. 2017 Aug;153(2):505-520. doi: 10.1053/j.gastro.2017.04.017. Epub 2017 Apr 20.


Inhibitory effects of resveratrol on hepatitis B virus X protein-induced hepatocellular carcinoma.

Park S, Lim J, Kim JR, Cho S.

J Vet Sci. 2017 Dec 31;18(4):419-429. doi: 10.4142/jvs.2017.18.4.419.

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