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Items: 1 to 20 of 28


Impact of Mesenchymal Stem Cells and Vitamin D on Transforming Growth Factor Beta Signaling Pathway in Hepatocellular Carcinoma in Rats

Saad El-Din S, Fouad H, Rashed LA, Mahfouz S, Hussein RE.

Asian Pac J Cancer Prev. 2018 Apr 25;19(4):905-912.


Circulating Tumor Cells from Different Vascular Sites Exhibit Spatial Heterogeneity in Epithelial and Mesenchymal Composition and Distinct Clinical Significance in Hepatocellular Carcinoma.

Sun YF, Guo W, Xu Y, Shi YH, Gong ZJ, Ji Y, Du M, Zhang X, Hu B, Huang A, Chen GG, Lai PBS, Cao Y, Qiu SJ, Zhou J, Yang XR, Fan J.

Clin Cancer Res. 2018 Feb 1;24(3):547-559. doi: 10.1158/1078-0432.CCR-17-1063. Epub 2017 Oct 25.


Transforming Growth Factor-β Promotes Liver Tumorigenesis in Mice via Up-regulation of Snail.

Moon H, Ju HL, Chung SI, Cho KJ, Eun JW, Nam SW, Han KH, Calvisi DF, Ro SW.

Gastroenterology. 2017 Nov;153(5):1378-1391.e6. doi: 10.1053/j.gastro.2017.07.014. Epub 2017 Jul 20.


Effect-enhancing and toxicity-reducing activity of usnic acid in ascitic tumor-bearing mice treated with bleomycin.

Su ZQ, Liu YH, Guo HZ, Sun CY, Xie JH, Li YC, Chen JN, Lai XP, Su ZR, Chen HM.

Int Immunopharmacol. 2017 May;46:146-155. doi: 10.1016/j.intimp.2017.03.004. Epub 2017 Mar 8.


Proteinase-activated receptor 2 (PAR2) in hepatic stellate cells - evidence for a role in hepatocellular carcinoma growth in vivo.

Mußbach F, Ungefroren H, Günther B, Katenkamp K, Henklein P, Westermann M, Settmacher U, Lenk L, Sebens S, Müller JP, Böhmer FD, Kaufmann R.

Mol Cancer. 2016 Jul 29;15(1):54. doi: 10.1186/s12943-016-0538-y.


Hepatitis B virus X protein amplifies TGF-β promotion on HCC motility through down-regulating PPM1a.

Liu Y, Xu Y, Ma H, Wang B, Xu L, Zhang H, Song X, Gao L, Liang X, Ma C.

Oncotarget. 2016 May 31;7(22):33125-35. doi: 10.18632/oncotarget.8884.


SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma.

Hernanda PY, Chen K, Das AM, Sideras K, Wang W, Li J, Cao W, Bots SJ, Kodach LL, de Man RA, Ijzermans JN, Janssen HL, Stubbs AP, Sprengers D, Bruno MJ, Metselaar HJ, ten Hagen TL, Kwekkeboom J, Peppelenbosch MP, Pan Q.

Oncogene. 2015 Sep 24;34(39):5055-68. doi: 10.1038/onc.2014.425. Epub 2014 Dec 22.


Reduced expression of transcriptional intermediary factor 1 gamma promotes metastasis and indicates poor prognosis of hepatocellular carcinoma.

Ding ZY, Jin GN, Wang W, Chen WX, Wu YH, Ai X, Chen L, Zhang WG, Liang HF, Laurence A, Zhang MZ, Datta PK, Zhang B, Chen XP.

Hepatology. 2014 Nov;60(5):1620-36. doi: 10.1002/hep.27273. Epub 2014 Sep 25.


[Establishment of a high metastatic potential human hepatocellular carcinoma orthotopic transplantation model with palliative liver resection in nude mice].

Huang XY, Huang ZL, Xu YH, Huang XY, Zhou J, Ye SL, Fan J, Tang ZY, Zheng Q.

Zhonghua Gan Zang Bing Za Zhi. 2013 Aug;21(8):604-8. doi: 10.3760/cma.j.issn.1007-3418.2013.08.010. Chinese.


Coffee consumption delays the hepatitis and suppresses the inflammation related gene expression in the Long-Evans Cinnamon rat.

Katayama M, Donai K, Sakakibara H, Ohtomo Y, Miyagawa M, Kuroda K, Kodama H, Suzuki K, Kasai N, Nishimori K, Uchida T, Watanabe K, Aso H, Isogai E, Sone H, Fukuda T.

Clin Nutr. 2014 Apr;33(2):302-10. doi: 10.1016/j.clnu.2013.05.006. Epub 2013 May 17.


TGF-β1 and hypoxia-dependent expression of MKP-1 leads tumor resistance to death receptor-mediated cell death.

Park J, Lee J, Kang W, Chang S, Shin EC, Choi C.

Cell Death Dis. 2013 Feb 28;4:e521. doi: 10.1038/cddis.2013.42.


Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1.

Yang L, Inokuchi S, Roh YS, Song J, Loomba R, Park EJ, Seki E.

Gastroenterology. 2013 May;144(5):1042-1054.e4. doi: 10.1053/j.gastro.2013.01.056. Epub 2013 Feb 4.


Involvement of PTEN/Akt signaling and oxidative stress on indole-3-carbinol (I3C)-induced hepatocarcinogenesis in rats.

Yamamoto R, Shimamoto K, Ishii Y, Kimura M, Fujii Y, Morita R, Suzuki K, Shibutani M, Mitsumori K.

Exp Toxicol Pathol. 2013 Sep;65(6):845-52. doi: 10.1016/j.etp.2012.12.003. Epub 2013 Jan 4.


TGF beta1 and related-Smads contribute to pulmonary metastasis of hepatocellular carcinoma in mice model.

Li GC, Ye QH, Dong QZ, Ren N, Jia HL, Qin LX.

J Exp Clin Cancer Res. 2012 Nov 14;31:93. doi: 10.1186/1756-9966-31-93.


Disruption of Smad-dependent signaling for growth of GST-P-positive lesions from the early stage in a rat two-stage hepatocarcinogenesis model.

Ichimura R, Mizukami S, Takahashi M, Taniai E, Kemmochi S, Mitsumori K, Shibutani M.

Toxicol Appl Pharmacol. 2010 Aug 1;246(3):128-40. doi: 10.1016/j.taap.2010.04.016. Epub 2010 Apr 25.


[Effects of Smad4 on liver fibrosis and hepatocarcinogenesis in mice treated with CCl4/ethanol].

Xu XB, He ZP, Leng XS, Liang ZQ, Peng JR, Zhang HY, Zhang HY, Xiao M, Zhang H, Liu CL, Zhang XD.

Zhonghua Gan Zang Bing Za Zhi. 2010 Feb;18(2):119-23. doi: 10.3760/cma.j.issn.1007-3418.2010.02.010. Chinese.


Loss of steroid receptor co-activator-3 attenuates carbon tetrachloride-induced murine hepatic injury and fibrosis.

Ma X, Xu L, Wang S, Chen H, Xu J, Li X, Ning G.

Lab Invest. 2009 Aug;89(8):903-14. doi: 10.1038/labinvest.2009.51. Epub 2009 Jun 1.


Tranilast inhibits the growth and metastasis of mammary carcinoma.

Chakrabarti R, Subramaniam V, Abdalla S, Jothy S, Prud'homme GJ.

Anticancer Drugs. 2009 Jun;20(5):334-45. doi: 10.1097/CAD.0b013e328327994e.


Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway.

Ding L, Wang Z, Yan J, Yang X, Liu A, Qiu W, Zhu J, Han J, Zhang H, Lin J, Cheng L, Qin X, Niu C, Yuan B, Wang X, Zhu C, Zhou Y, Li J, Song H, Huang C, Ye Q.

J Clin Invest. 2009 Feb;119(2):349-61. doi: 10.1172/JCI35930. Epub 2009 Jan 12.


Cross-talk between IFN-alpha and TGF-beta1 signaling pathways in preneoplastic rat liver.

Alvarez Mde L, Quiroga AD, Parody JP, Ronco MT, Francés DE, Carnovale CE, Carrillo MC.

Growth Factors. 2009 Feb;27(1):1-11. doi: 10.1080/08977190802547357.


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