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Items: 4


Gene Network Analysis of Glucose Linked Signaling Pathways and Their Role in Human Hepatocellular Carcinoma Cell Growth and Survival in HuH7 and HepG2 Cell Lines.

Berger E, Vega N, Weiss-Gayet M, Géloën A.

Biomed Res Int. 2015;2015:821761. doi: 10.1155/2015/821761. Epub 2015 Aug 24.


SIRT1/PGC1α-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer.

Vellinga TT, Borovski T, de Boer VC, Fatrai S, van Schelven S, Trumpi K, Verheem A, Snoeren N, Emmink BL, Koster J, Rinkes IH, Kranenburg O.

Clin Cancer Res. 2015 Jun 15;21(12):2870-9. doi: 10.1158/1078-0432.CCR-14-2290. Epub 2015 Mar 16.


PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis.

Bhalla K, Hwang BJ, Dewi RE, Ou L, Twaddel W, Fang HB, Vafai SB, Vazquez F, Puigserver P, Boros L, Girnun GD.

Cancer Res. 2011 Nov 1;71(21):6888-98. doi: 10.1158/0008-5472.CAN-11-1011. Epub 2011 Sep 13.


Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.

Martínez-Jiménez CP, Gómez-Lechón MJ, Castell JV, Jover R.

J Biol Chem. 2006 Oct 6;281(40):29840-9. Epub 2006 Aug 4.

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